Hopkins PN, Hunt SC: Genetics of hypertension. Genet Med. 2003, 5 (6): 413-429.
Article
PubMed
Google Scholar
Frohlich ED, Varagic J: Sodium directly impairs target organ function in hypertension. Curr Opin Cardiol. 2005, 20 (5): 424-429. 10.1097/01.hco.0000175519.34933.a5.
Article
PubMed
Google Scholar
Kubo T: [Mechanisms of hypertension in the central nervous system]. Yakugaku Zasshi. 2006, 126 (9): 695-709. 10.1248/yakushi.126.695.
Article
CAS
PubMed
Google Scholar
Izzard AS, Rizzoni D, Agabiti-Rosei E, Heagerty AM: Small artery structure and hypertension: adaptive changes and target organ damage. J Hypertens. 2005, 23 (2): 247-250. 10.1097/00004872-200502000-00002.
Article
CAS
PubMed
Google Scholar
Laurent S, Boutouyrie P, Lacolley P: Structural and genetic bases of arterial stiffness. Hypertension. 2005, 45 (6): 1050-1055. 10.1161/01.HYP.0000164580.39991.3d.
Article
CAS
PubMed
Google Scholar
North KE, MacCluer JW, Devereux RB, Howard BV, Welty TK, Best LG, Lee ET, Fabsitz RR, Roman MJ: Heritability of carotid artery structure and function: the Strong Heart Family Study. Arterioscler Thromb Vasc Biol. 2002, 22 (10): 1698-1703. 10.1161/01.ATV.0000032656.91352.5E.
Article
CAS
PubMed
Google Scholar
Lerman LO, Chade AR, Sica V, Napoli C: Animal models of hypertension: an overview. J Lab Clin Med. 2005, 146 (3): 160-173. 10.1016/j.lab.2005.05.005.
Article
CAS
PubMed
Google Scholar
Mangos GJ, Turner SW, Fraser TB, Whitworth JA: The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat. J Hypertens. 2000, 18 (12): 1849-1855. 10.1097/00004872-200018120-00020.
Article
CAS
PubMed
Google Scholar
Connell JM, Whitworth JA, Davies DL, Lever AF, Richards AM, Fraser R: Effects of ACTH and cortisol administration on blood pressure, electrolyte metabolism, atrial natriuretic peptide and renal function in normal man. J Hypertens. 1987, 5 (4): 425-433. 10.1097/00004872-198708000-00007.
Article
CAS
PubMed
Google Scholar
Whitworth JA, Schyvens CG, Zhang Y, Andrews MC, Mangos GJ, Kelly JJ: The nitric oxide system in glucocorticoid-induced hypertension. J Hypertens. 2002, 20 (6): 1035-1043. 10.1097/00004872-200206000-00003.
Article
CAS
PubMed
Google Scholar
Zhang Y, Chan MM, Andrews MC, Mori TA, Croft KD, McKenzie KU, Schyvens CG, Whitworth JA: Apocynin but not allopurinol prevents and reverses adrenocorticotropic hormone-induced hypertension in the rat. Am J Hypertens. 2005, 18 (7): 910-916. 10.1016/j.amjhyper.2005.02.017.
Article
CAS
PubMed
Google Scholar
Ulker S, McKeown PP, Bayraktutan U: Vitamins reverse endothelial dysfunction through regulation of eNOS and NAD(P)H oxidase activities. Hypertension. 2003, 41 (3): 534-539. 10.1161/01.HYP.0000057421.28533.37.
Article
PubMed
Google Scholar
Demirci B, McKeown PP, Bayraktutan U: Blockade of angiotensin II provides additional benefits in hypertension- and ageing-related cardiac and vascular dysfunctions beyond its blood pressure-lowering effects. J Hypertens. 2005, 23 (12): 2219-2227. 10.1097/01.hjh.0000191906.03983.ee.
Article
CAS
PubMed
Google Scholar
Mulvany MJ, Baumbach GL, Aalkjaer C, Heagerty AM, Korsgaard N, Schiffrin EL, Heistad DD: Vascular remodeling. Hypertension. 1996, 28 (3): 505-506.
CAS
PubMed
Google Scholar
Arribas SM, Hillier C, Gonzalez C, McGrory S, Dominiczak AF, McGrath JC: Cellular aspects of vascular remodeling in hypertension revealed by confocal microscopy. Hypertension. 1997, 30 (6): 1455-1464.
Article
CAS
PubMed
Google Scholar
Huttner I, Costabella PM, De Chastonay C, Gabbiani G: Volume, surface, and junctions of rat aortic endothelium during experimental hypertension: a morphometric and freeze fracture study. Lab Invest. 1982, 46 (5): 489-504.
CAS
PubMed
Google Scholar
Rummery NM, McKenzie KU, Whitworth JA, Hill CE: Decreased endothelial size and connexin expression in rat caudal arteries during hypertension. J Hypertens. 2002, 20 (2): 247-253. 10.1097/00004872-200202000-00014.
Article
CAS
PubMed
Google Scholar
Schiffrin EL, Touyz RM: From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension. Am J Physiol Heart Circ Physiol. 2004, 287 (2): H435-46. 10.1152/ajpheart.00262.2004.
Article
CAS
PubMed
Google Scholar
Touyz RM: Intracellular mechanisms involved in vascular remodelling of resistance arteries in hypertension: role of angiotensin II. Exp Physiol. 2005, 90 (4): 449-455. 10.1113/expphysiol.2005.030080.
Article
CAS
PubMed
Google Scholar
Inoue T, Masuda T, Kishi K: Structural and functional alterations of mesenteric vascular beds in spontaneously hypertensive rats. Jpn Heart J. 1990, 31 (3): 393-403.
Article
CAS
PubMed
Google Scholar
Intengan HD, Thibault G, Li JS, Schiffrin EL: Resistance artery mechanics, structure, and extracellular components in spontaneously hypertensive rats : effects of angiotensin receptor antagonism and converting enzyme inhibition. Circulation. 1999, 100 (22): 2267-2275.
Article
CAS
PubMed
Google Scholar
Sandow SL, Bramich NJ, Bandi HP, Rummery NM, Hill CE: Structure, function, and endothelium-derived hyperpolarizing factor in the caudal artery of the SHR and WKY rat. Arterioscler Thromb Vasc Biol. 2003, 23 (5): 822-828. 10.1161/01.ATV.0000067425.06019.D7.
Article
CAS
PubMed
Google Scholar
Yang L, Gao YJ, Lee RM: Quinapril effects on resistance artery structure and function in hypertension. Naunyn Schmiedebergs Arch Pharmacol. 2004, 370 (6): 444-451. 10.1007/s00210-004-0990-x.
Article
CAS
PubMed
Google Scholar
Westhoff TH, Scheid S, Tolle M, Kaynak B, Schmidt S, Zidek W, Sperling S, van der Giet M: A physiogenomic approach to study the regulation of blood pressure. Physiol Genomics. 2005, 23 (1): 46-53. 10.1152/physiolgenomics.00077.2005.
Article
CAS
PubMed
Google Scholar
NCBI Gene Expression Omnibus. [http://www.ncbi.nlm.nih.gov/geo/]
Choe SE, Boutros M, Michelson AM, Church GM, Halfon MS: Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset. Genome Biol. 2005, 6 (2): R16-10.1186/gb-2005-6-2-r16.
Article
PubMed Central
PubMed
Google Scholar
Hnasko R, Lisanti MP: The biology of caveolae: lessons from caveolin knockout mice and implications for human disease. Mol Interv. 2003, 3 (8): 445-464. 10.1124/mi.3.8.445.
Article
CAS
PubMed
Google Scholar
Wieland T, Mittmann C: Regulators of G-protein signalling: multifunctional proteins with impact on signalling in the cardiovascular system. Pharmacol Ther. 2003, 97 (2): 95-115. 10.1016/S0163-7258(02)00326-1.
Article
CAS
PubMed
Google Scholar
Rummery NM, Hickey H, McGurk G, Hill CE: Connexin37 is the major connexin expressed in the media of caudal artery. Arterioscler Thromb Vasc Biol. 2002, 22 (9): 1427-1432. 10.1161/01.ATV.0000028814.45706.E5.
Article
CAS
PubMed
Google Scholar
Goto K, Rummery NM, Grayson TH, Hill CE: Attenuation of conducted vasodilatation in rat mesenteric arteries during hypertension: role of inwardly rectifying potassium channels. J Physiol. 2004, 561 (Pt 1): 215-231. 10.1113/jphysiol.2004.070458.
Article
CAS
PubMed Central
PubMed
Google Scholar
Rummery NM, Grayson TH, Hill CE: Angiotensin-converting enzyme inhibition restores endothelial but not medial connexin expression in hypertensive rats. J Hypertens. 2005, 23 (2): 317-328. 10.1097/00004872-200502000-00014.
Article
CAS
PubMed
Google Scholar
Papparella I, Ceolotto G, Lenzini L, Mazzoni M, Franco L, Sartori M, Ciccariello L, Semplicini A: Angiotensin II-induced over-activation of p47phox in fibroblasts from hypertensives: which role in the enhanced ERK1/2 responsiveness to angiotensin II?. J Hypertens. 2005, 23 (4): 793-800. 10.1097/01.hjh.0000163148.97459.9d.
Article
CAS
PubMed
Google Scholar
Ono K, Han J: The p38 signal transduction pathway: activation and function. Cell Signal. 2000, 12 (1): 1-13. 10.1016/S0898-6568(99)00071-6.
Article
CAS
PubMed
Google Scholar
Safar ME: Systolic hypertension in the elderly: arterial wall mechanical properties and the renin-angiotensin-aldosterone system. J Hypertens. 2005, 23 (4): 673-681. 10.1097/01.hjh.0000163130.39149.fe.
Article
CAS
PubMed
Google Scholar
Kamm KE, Stull JT: Dedicated myosin light chain kinases with diverse cellular functions. J Biol Chem. 2001, 276 (7): 4527-4530. 10.1074/jbc.R000028200.
Article
CAS
PubMed
Google Scholar
Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, Kurzchalia TV: Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science. 2001, 293 (5539): 2449-2452. 10.1126/science.1062688.
Article
CAS
PubMed
Google Scholar
Gratton JP, Bernatchez P, Sessa WC: Caveolae and caveolins in the cardiovascular system. Circ Res. 2004, 94 (11): 1408-1417. 10.1161/01.RES.0000129178.56294.17.
Article
CAS
PubMed
Google Scholar
Patel HH, Zhang S, Murray F, Suda RY, Head BP, Yokoyama U, Swaney JS, Niesman IR, Schermuly RT, Pullamsetti SS, Thistlethwaite PA, Miyanohara A, Farquhar MG, Yuan JX, Insel PA: Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension. Faseb J. 2007, 21 (11): 2970-2979. 10.1096/fj.07-8424com.
Article
PubMed
Google Scholar
Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ, Steinberg TH, Wyss JM, Mecham RP, Blumer KJ: Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. J Clin Invest. 2003, 111 (4): 445-452. 10.1172/JCI200315598.
Article
CAS
PubMed Central
PubMed
Google Scholar
Tang KM, Wang GR, Lu P, Karas RH, Aronovitz M, Heximer SP, Kaltenbronn KM, Blumer KJ, Siderovski DP, Zhu Y, Mendelsohn ME: Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure. Nat Med. 2003, 9 (12): 1506-1512. 10.1038/nm958.
Article
CAS
PubMed
Google Scholar
Sun X, Kaltenbronn KM, Steinberg TH, Blumer KJ: RGS2 is a mediator of nitric oxide action on blood pressure and vasoconstrictor signaling. Mol Pharmacol. 2005, 67 (3): 631-639. 10.1124/mol.104.007724.
Article
CAS
PubMed
Google Scholar
Dupuis M, Soubrier F, Brocheriou I, Raoux S, Haloui M, Louedec L, Michel JB, Nadaud S: Profiling of aortic smooth muscle cell gene expression in response to chronic inhibition of nitric oxide synthase in rats. Circulation. 2004, 110 (7): 867-873. 10.1161/01.CIR.0000138850.72900.FE.
Article
CAS
PubMed
Google Scholar
Adams LD, Geary RL, McManus B, Schwartz SM: A comparison of aorta and vena cava medial message expression by cDNA array analysis identifies a set of 68 consistently differentially expressed genes, all in aortic media. Circ Res. 2000, 87 (7): 623-631.
Article
CAS
PubMed
Google Scholar
Li J, Adams LD, Wang X, Pabon L, Schwartz SM, Sane DC, Geary RL: Regulator of G protein signaling 5 marks peripheral arterial smooth muscle cells and is downregulated in atherosclerotic plaque. J Vasc Surg. 2004, 40 (3): 519-528. 10.1016/j.jvs.2004.06.021.
Article
PubMed
Google Scholar
Berger M, Bergers G, Arnold B, Hammerling GJ, Ganss R: Regulator of G-protein signaling-5 induction in pericytes coincides with active vessel remodeling during neovascularization. Blood. 2005, 105 (3): 1094-1101. 10.1182/blood-2004-06-2315.
Article
CAS
PubMed
Google Scholar
Kirsch T, Wellner M, Luft FC, Haller H, Lippoldt A: Altered gene expression in cerebral capillaries of stroke-prone spontaneously hypertensive rats. Brain Res. 2001, 910 (1-2): 106-115. 10.1016/S0006-8993(01)02670-1.
Article
CAS
PubMed
Google Scholar
Christensen KL, Mulvany MJ: Location of resistance arteries. J Vasc Res. 2001, 38 (1): 1-12. 10.1159/000051024.
Article
CAS
PubMed
Google Scholar
Sandow SL, Tare M, Coleman HA, Hill CE, Parkington HC: Involvement of myoendothelial gap junctions in the actions of endothelium-derived hyperpolarizing factor. Circ Res. 2002, 90 (10): 1108-1113. 10.1161/01.RES.0000019756.88731.83.
Article
CAS
PubMed
Google Scholar
Sandow SL, Goto K, Rummery NM, Hill CE: Developmental changes in myoendothelial gap junction mediated vasodilator activity in the rat saphenous artery. J Physiol. 2004, 556 (Pt 3): 875-886. 10.1113/jphysiol.2003.058669.
Article
CAS
PubMed Central
PubMed
Google Scholar
Wit E, McClure J: Statistics for Microarrays: Design, Analysis and Inference. 2004, John Wiley and Sons, Ltd.
Chapter
Google Scholar
Imbeaud S, Graudens E, Boulanger V, Barlet X, Zaborski P, Eveno E, Mueller O, Schroeder A, Auffray C: Towards standardization of RNA quality assessment using user-independent classifiers of microcapillary electrophoresis traces. Nucleic Acids Res. 2005, 33 (6): e56-10.1093/nar/gni054.
Article
PubMed Central
PubMed
Google Scholar
Affymetrix. [http://www.affymetrix.com/index.affx]
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J: Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004, 5 (10): R80-10.1186/gb-2004-5-10-r80.
Article
PubMed Central
PubMed
Google Scholar
The Centre for Bioinformation Science. [http://dayhoff.anu.edu.au/software.html]
Pittelkow YE, Wilson SR: Visualisation of gene expression data - the GE-biplot, the Chip-plot and the Gene-plot. Stat Appl Genet Mol Biol. 2003, 2: Article6-
PubMed
Google Scholar
Dudoit S, Gentleman RC, Quackenbush J: Open source software for the analysis of microarray data. Biotechniques. 2003, Suppl: 45-51.
PubMed
Google Scholar
Rummery NM, Hill CE: Vascular gap junctions and implications for hypertension. Clin Exp Pharmacol Physiol. 2004, 31 (10): 659-667. 10.1111/j.1440-1681.2004.04071.x.
Article
CAS
PubMed
Google Scholar
National Center for Biotechnology Information. [http://www.ncbi.nlm.nih.gov/]
Human Protein Reference Database. [http://www.hprd.org]
Peri S, Navarro JD, Amanchy R, Kristiansen TZ, Jonnalagadda CK, Surendranath V, Niranjan V, Muthusamy B, Gandhi TK, Gronborg M, Ibarrola N, Deshpande N, Shanker K, Shivashankar HN, Rashmi BP, Ramya MA, Zhao Z, Chandrika KN, Padma N, Harsha HC, Yatish AJ, Kavitha MP, Menezes M, Choudhury DR, Suresh S, Ghosh N, Saravana R, Chandran S, Krishna S, Joy M, Anand SK, Madavan V, Joseph A, Wong GW, Schiemann WP, Constantinescu SN, Huang L, Khosravi-Far R, Steen H, Tewari M, Ghaffari S, Blobe GC, Dang CV, Garcia JG, Pevsner J, Jensen ON, Roepstorff P, Deshpande KS, Chinnaiyan AM, Hamosh A, Chakravarti A, Pandey A: Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res. 2003, 13 (10): 2363-2371. 10.1101/gr.1680803.
Article
CAS
PubMed Central
PubMed
Google Scholar