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Table 1 Discriminatory key to classify indecisive isoforms.

From: Comparative analysis of cyanobacterial superoxide dismutases to discriminate canonical forms

Characteristics

FeSOD

MnSOD

Metal specificity

Fe

Mn

Amino acid length

199–229

200–316

Theoretical molecular weight

21–25 KDa

22–34 KDa

No. of a helix*

13

14

No. of b strand*

3

3

Domains

N & C terminal

N & C terminal

Motif

DVWEHAYY

DVWEHAYY

Active site residues*

Fig 3

Fig 4

Structurally highly conserved metal specific residues

F184XXXA188Q189.......T280......F/Y303

R184XXXG188G189.......G280......W303

Conserved residue with photosynthetic role

K87, K139

None

Transmembrane hydrophobic pocket

Absent

Present

  1. * – Based on the structural analysis of MnSOD of Anabaena sp. (PDB No: 1gv3) and FeSOD of Thermosynechococcus elongatus BP-1 (PDB No: 1my6)