Friedenstein AJ, Deriglasova UF, Kulagina NN, Panasuk AF, Rudakowa SF, Luria EA, Ruadkow IA: Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method. Exp Hematol. 1974, 2 (2): 83-92.
CAS
PubMed
Google Scholar
Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR: Multilineage potential of adult human mesenchymal stem cells. Science. 1999, 284 (5411): 143-147. 10.1126/science.284.5411.143.
Article
CAS
PubMed
Google Scholar
Etheridge SL, Spencer GJ, Heath DJ, Genever PG: Expression profiling and functional analysis of wnt signaling mechanisms in mesenchymal stem cells. Stem Cells. 2004, 22 (5): 849-860. 10.1634/stemcells.22-5-849.
Article
CAS
PubMed
Google Scholar
Devine SM, Hoffman R: Role of mesenchymal stem cells in hematopoietic stem cell transplantation. Curr Opin Hematol. 2000, 7 (6): 358-363. 10.1097/00062752-200011000-00007.
Article
CAS
PubMed
Google Scholar
Wilson A, Trumpp A: Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol. 2006, 6 (2): 93-106. 10.1038/nri1779.
Article
CAS
PubMed
Google Scholar
Lerner C, Harrison DE: 5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation. Exp Hematol. 1990, 18 (2): 114-118.
CAS
PubMed
Google Scholar
Zhang J, Niu C, Ye L, Huang H, He X, Tong WG, Ross J, Haug J, Johnson T, Feng JQ, Harris S, Wiedemann LM, Mishina Y, Li L: Identification of the haematopoietic stem cell niche and control of the niche size. Nature. 2003, 425 (6960): 836-841. 10.1038/nature02041.
Article
CAS
PubMed
Google Scholar
Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, Grisanti S, Gianni AM: Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood. 2002, 99 (10): 3838-3843. 10.1182/blood.V99.10.3838.
Article
CAS
PubMed
Google Scholar
Krampera M, Glennie S, Dyson J, Scott D, Laylor R, Simpson E, Dazzi F: Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood. 2003, 101 (9): 3722-3729. 10.1182/blood-2002-07-2104.
Article
CAS
PubMed
Google Scholar
Tse WT, Pendleton JD, Beyer WM, Egalka MC, Guinan EC: Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation. 2003, 75 (3): 389-397. 10.1097/01.TP.0000045055.63901.A9.
Article
CAS
PubMed
Google Scholar
Corcione A, Benvenuto F, Ferretti E, Giunti D, Cappiello V, Cazzanti F, Risso M, Gualandi F, Mancardi GL, Pistoia V, Uccelli A: Human mesenchymal stem cells modulate B-cell functions. Blood. 2006, 107 (1): 367-372. 10.1182/blood-2005-07-2657.
Article
CAS
PubMed
Google Scholar
Glennie S, Soeiro I, Dyson PJ, Lam EW, Dazzi F: Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood. 2005, 105 (7): 2821-2827. 10.1182/blood-2004-09-3696.
Article
CAS
PubMed
Google Scholar
Zappia E, Casazza S, Pedemonte E, Benvenuto F, Bonanni I, Gerdoni E, Giunti D, Ceravolo A, Cazzanti F, Frassoni F, Mancardi G, Uccelli A: Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy. Blood. 2005, 106 (5): 1755-1761. 10.1182/blood-2005-04-1496.
Article
CAS
PubMed
Google Scholar
Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D: Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood. 2004, 103 (12): 4619-4621. 10.1182/blood-2003-11-3909.
Article
CAS
PubMed
Google Scholar
Aggarwal S, Pittenger MF: Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 2005, 105 (4): 1815-1822. 10.1182/blood-2004-04-1559.
Article
CAS
PubMed
Google Scholar
Le Blanc K, Rasmusson I, Gotherstrom C, Seidel C, Sundberg B, Sundin M, Rosendahl K, Tammik C, Ringden O: Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes. Scand J Immunol. 2004, 60 (3): 307-315. 10.1111/j.0300-9475.2004.01483.x.
Article
CAS
PubMed
Google Scholar
Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA: "Stemness": transcriptional profiling of embryonic and adult stem cells. Science. 2002, 298 (5593): 597-600. 10.1126/science.1072530.
Article
CAS
PubMed
Google Scholar
Phinney DG, Hill K, Michelson C, DuTreil M, Hughes C, Humphries S, Wilkinson R, Baddoo M, Bayly E: Biological activities encoded by the murine mesenchymal stem cell transcriptome provide a basis for their developmental potential and broad therapeutic efficacy. Stem Cells. 2006, 24 (1): 186-198. 10.1634/stemcells.2004-0236.
Article
PubMed
Google Scholar
Wagner W, Wein F, Seckinger A, Frankhauser M, Wirkner U, Krause U, Blake J, Schwager C, Eckstein V, Ansorge W, Ho AD: Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood. Exp Hematol. 2005, 33 (11): 1402-1416. 10.1016/j.exphem.2005.07.003.
Article
CAS
PubMed
Google Scholar
Jackson A, Vayssiere B, Garcia T, Newell W, Baron R, Roman-Roman S, Rawadi G: Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells. Bone. 2005, 36 (4): 585-598. 10.1016/j.bone.2005.01.007.
Article
CAS
PubMed
Google Scholar
Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF, Freeman MW, Seed B, Jensen R, Church GM, Hovig E, Cepko CL, Park P, Ohno-Machado L, Jenssen TK: A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies. Nat Biotechnol. 2006, 24 (7): 832-840. 10.1038/nbt1217.
Article
CAS
PubMed
Google Scholar
Lengner CJ, Lepper C, van Wijnen AJ, Stein JL, Stein GS, Lian JB: Primary mouse embryonic fibroblasts: a model of mesenchymal cartilage formation. J Cell Physiol. 2004, 200 (3): 327-333. 10.1002/jcp.20118.
Article
CAS
PubMed
Google Scholar
Panepucci RA, Siufi JL, Silva WA, Proto-Siquiera R, Neder L, Orellana M, Rocha V, Covas DT, Zago MA: Comparison of gene expression of umbilical cord vein and bone marrow-derived mesenchymal stem cells. Stem Cells. 2004, 22 (7): 1263-1278. 10.1634/stemcells.2004-0024.
Article
CAS
PubMed
Google Scholar
Ridgeway AG, Petropoulos H, Wilton S, Skerjanc IS: Wnt signaling regulates the function of MyoD and myogenin. J Biol Chem. 2000, 275 (42): 32398-32405. 10.1074/jbc.M004349200.
Article
CAS
PubMed
Google Scholar
Rudnicki JA, Brown AM: Inhibition of chondrogenesis by Wnt gene expression in vivo and in vitro. Dev Biol. 1997, 185 (1): 104-118. 10.1006/dbio.1997.8536.
Article
CAS
PubMed
Google Scholar
Ross SE, Hemati N, Longo KA, Bennett CN, Lucas PC, Erickson RL, MacDougald OA: Inhibition of adipogenesis by Wnt signaling. Science. 2000, 289 (5481): 950-953. 10.1126/science.289.5481.950.
Article
CAS
PubMed
Google Scholar
Hartmann C: A Wnt canon orchestrating osteoblastogenesis. Trends Cell Biol. 2006, 16 (3): 151-158. 10.1016/j.tcb.2006.01.001.
Article
CAS
PubMed
Google Scholar
Song L, Webb NE, Song Y, Tuan RS: Identification and functional analysis of candidate genes regulating mesenchymal stem cell self-renewal and multipotency. Stem Cells. 2006, 24 (7): 1707-1718. 10.1634/stemcells.2005-0604.
Article
PubMed
Google Scholar
Ramirez-Castillejo C, Sanchez-Sanchez F, Andreu-Agullo C, Ferron SR, Aroca-Aguilar JD, Sanchez P, Mira H, Escribano J, Farinas I: Pigment epithelium-derived factor is a niche signal for neural stem cell renewal. Nat Neurosci. 2006, 9 (3): 331-339. 10.1038/nn1657.
Article
CAS
PubMed
Google Scholar
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES: A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 2006, 125 (2): 315-326. 10.1016/j.cell.2006.02.041.
Article
CAS
PubMed
Google Scholar
Oostendorp RA, Robin C, Steinhoff C, Marz S, Brauer R, Nuber UA, Dzierzak EA, Peschel C: Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures. Stem Cells. 2005, 23 (6): 842-851. 10.1634/stemcells.2004-0120.
Article
CAS
PubMed
Google Scholar
Jones N, Iljin K, Dumont DJ, Alitalo K: Tie receptors: new modulators of angiogenic and lymphangiogenic responses. Nat Rev Mol Cell Biol. 2001, 2 (4): 257-267. 10.1038/35067005.
Article
CAS
PubMed
Google Scholar
Imhof BA, Aurrand-Lions M: Angiogenesis and inflammation face off. Nat Med. 2006, 12 (2): 171-172. 10.1038/nm0206-171.
Article
CAS
PubMed
Google Scholar
Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, Ito K, Koh GY, Suda T: Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell. 2004, 118 (2): 149-161. 10.1016/j.cell.2004.07.004.
Article
CAS
PubMed
Google Scholar
Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS: Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest. 2001, 107 (9): 1055-1061.
Article
CAS
PubMed Central
PubMed
Google Scholar
Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, Grunewald E, Cheng T, Dombkowski D, Calvi LM, Rittling SR, Scadden DT: Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med. 2005, 201 (11): 1781-1791. 10.1084/jem.20041992.
Article
CAS
PubMed Central
PubMed
Google Scholar
Nilsson SK, Johnston HM, Whitty GA, Williams B, Webb RJ, Denhardt DT, Bertoncello I, Bendall LJ, Simmons PJ, Haylock DN: Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood. 2005, 106 (4): 1232-1239. 10.1182/blood-2004-11-4422.
Article
CAS
PubMed
Google Scholar
Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L: The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science. 2001, 294 (5547): 1731-1735. 10.1126/science.1062960.
Article
CAS
PubMed
Google Scholar
Li Z, Calzada MJ, Sipes JM, Cashel JA, Krutzsch HC, Annis DS, Mosher DF, Roberts DD: Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior. J Cell Biol. 2002, 157 (3): 509-519. 10.1083/jcb.200109098.
Article
CAS
PubMed Central
PubMed
Google Scholar
Long MW, Dixit VM: Thrombospondin functions as a cytoadhesion molecule for human hematopoietic progenitor cells. Blood. 1990, 75 (12): 2311-2318.
CAS
PubMed
Google Scholar
Lawler J: The functions of thrombospondin-1 and-2. Curr Opin Cell Biol. 2000, 12 (5): 634-640. 10.1016/S0955-0674(00)00143-5.
Article
CAS
PubMed
Google Scholar
Hankenson KD, Bornstein P: The secreted protein thrombospondin 2 is an autocrine inhibitor of marrow stromal cell proliferation. J Bone Miner Res. 2002, 17 (3): 415-425. 10.1359/jbmr.2002.17.3.415.
Article
CAS
PubMed
Google Scholar
Hurley RW, McCarthy JB, Verfaillie CM: Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation. J Clin Invest. 1995, 96 (1): 511-519.
Article
CAS
PubMed Central
PubMed
Google Scholar
Rabinovich GA, Ramhorst RE, Rubinstein N, Corigliano A, Daroqui MC, Kier-Joffe EB, Fainboim L: Induction of allogenic T-cell hyporesponsiveness by galectin-1-mediated apoptotic and non-apoptotic mechanisms. Cell Death Differ. 2002, 9 (6): 661-670. 10.1038/sj.cdd.4401009.
Article
CAS
PubMed
Google Scholar
Vas V, Fajka-Boja R, Ion G, Dudics V, Monostori E, Uher F: Biphasic effect of recombinant galectin-1 on the growth and death of early hematopoietic cells. Stem Cells. 2005, 23 (2): 279-287. 10.1634/stemcells.2004-0084.
Article
CAS
PubMed
Google Scholar
Sakaguchi M, Shingo T, Shimazaki T, Okano HJ, Shiwa M, Ishibashi S, Oguro H, Ninomiya M, Kadoya T, Horie H, Shibuya A, Mizusawa H, Poirier F, Nakauchi H, Sawamoto K, Okano H: A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proc Natl Acad Sci U S A. 2006, 103 (18): 7112-7117. 10.1073/pnas.0508793103.
Article
CAS
PubMed Central
PubMed
Google Scholar
Kikutani H, Kumanogoh A: Semaphorins in interactions between T cells and antigen-presenting cells. Nat Rev Immunol. 2003, 3 (2): 159-167. 10.1038/nri1003.
Article
CAS
PubMed
Google Scholar
Catalano A, Caprari P, Moretti S, Faronato M, Tamagnone L, Procopio A: Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function. Blood. 2006, 107 (8): 3321-3329. 10.1182/blood-2005-06-2445.
Article
CAS
PubMed
Google Scholar
Ramasamy R, Fazekasova H, Lam EW, Soeiro I, Lombardi G, Dazzi F: Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle. Transplantation. 2006,
Google Scholar
Scuteri A, Cassetti A, Tredici G: Adult mesenchymal stem cells rescue dorsal root ganglia neurons from dying. Brain Res. 2006, 1116 (1): 75-81. 10.1016/j.brainres.2006.07.127.
Article
CAS
PubMed
Google Scholar
Scadden DT: The stem-cell niche as an entity of action. Nature. 2006, 441 (7097): 1075-1079. 10.1038/nature04957.
Article
CAS
PubMed
Google Scholar
Martino G, Pluchino S: The therapeutic potential of neural stem cells. Nat Rev Neurosci. 2006, 7 (5): 395-406. 10.1038/nrn1908.
Article
CAS
PubMed
Google Scholar
Gene Expression Omnibus. [http://www.ncbi.nlm.nih.gov/geo/]
The Database for Annotation, Visualization and Integrated Discovery (DAVID). [http://david.abcc.ncifcrf.gov/summary.jsp]
Baranzini SE, Elfstrom C, Chang SY, Butunoi C, Murray R, Higuchi R, Oksenberg JR: Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression. J Immunol. 2000, 165 (11): 6576-6582.
Article
CAS
PubMed
Google Scholar