Impaired barrier function by dietary fructo-oligosaccharides (FOS) in rats is accompanied by increased colonic mitochondrial gene expression

Table 2 Detailed classification of biological processes affected by FOS.

Biological process		Number of genes affected by FOS*
Mitochondria	Complex I	27
	Complex II	5
	Complex III	2
	Complex IV	13
	Complex V	21
	Metabolism and TCA cycle	53
	Mitochondrial ribosomes	33
	Protein transport	11
	Miscellaneous	12
Protein turnover	Protein degradation	31
	Translation	44
	Protein maturation	32
	Miscellaneous	6
Transcription	Chromatin related	22
	mRNA metabolism	7
	Transcription	26
	Miscellaneous	6
Cell turnover	Apoptosis	19
	Growth/Differentiation	16
Mucosal barrier		30
Cytoskeleton		26
Transport		20
Oxidative stress		16
Vesicle related		10
Peptide hormones		6
Other†		503
		997

* Genes with p-value < 0.001 or selected by RF threshold
† Genes with less than 5 other genes belonging to the same process, unknown genes and, genes not part of a known process.

ISSN: 1471-2164