From: Integrative analysis of RUNX1 downstream pathways and target genes
 | FPD | CBF | E8.5 | E12 |
---|---|---|---|---|
GO: Biological processes | Immune response p = 6.5 × 10 -5 36 genes | Macromolecular complex assembly p = 0.02 47 genes | Blood vessel development p = 0.06 15 genes | Response to external stimulus* p = 0.0003 18 genes |
 | Negative regulation of apoptosis p = 0.002 16 genes | Cell growth p = 0.02 21 genes |  | Behavior p = 0.0003 14 genes |
 | Response to biotic stimulus p = 0.002 19 genes |  |  | Immune system process p = 0.0006 18 genes |
 | Cell proliferation p = 0.01 36 genes |  |  |  |
GO: Molecular functions | Cadmium ion binding p = 0.002 4 genes | RNA binding p = 0.03 50 genes | Â | IgG binding p = 0.006 3 genes |
 |  | Cadmium ion binding p = 0.03 4 genes |  | Ferric-chelate reductase activity p = 0.03 2 genes |
 |  |  |  | Polysaccharide binding p = 0.03 6 genes |
GO: cellular component | Â | Spindle p = 0.06 11 genes | Cell junction p = 0.06 14 genes | Cell surface p = 0.05 9 genes |
 |  |  |  | Extracellular space p = 0.06 37 genes |
InterPro motifs (FatiGo) | Vertebrate metallothionein p = 0.0001 | Vertebrate metallothionein p = 0.02 | Â | Â |
 |  | Tubulin p = 0.04 |  |  |