Table 1 Effect of annotation and intensity based filters on the selection of TP and reduction of unspliced exon set (TN).
From: Dissecting an alternative splicing analysis workflow for GeneChip®Exon 1.0 ST Affymetrix arrays
| Splicing set | Splicing set | Splicing set | ||||
|---|---|---|---|---|---|---|
| 128.32 vs 512 | 32.2 vs 128 | 2.0 vs 32 | ||||
|
TP (Sensitivity) |
TN (Specificity) |
TP (Sensitivity) |
TN (Specificity) |
TP (Sensitivity) |
TN (Specificity) | |
| Cross Hybridization filter |
172 (1.00) |
228264 (1.00) |
195 (1.00) |
228264 (1.00) |
179 (1.00) |
228264 (1.00) |
| Multiple mRNAs filter |
172 (1.00) |
71037 (0.31) |
195 (1.00) |
71037 (0.31) |
179 (1.00) |
71037 (0.31) |
|
DABG filter (DABG p-value ≤ 0.05 in 90% arrays) |
172 (1.00) |
197951 (0.86) |
185 (0.95) |
197951 (0.86) |
170 (0.95) |
197951 (0.86) |
