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Erratum to: An integrative genomics approach for identifying novel functional consequences of PBRM1 truncated mutations in clear cell renal cell carcinoma (ccRCC)

BMC Genomicsvolume 17, Article number: 821 (2016) | Download Citation

The original article was published in BMC Genomics 2016 17:515

Erratum

Following publication of the original article [1] it was brought to our attention that there were three errors in the “Results” section of the article’s abstract. Please see below for the two sentences in which these errors occur:

1. We identified 613 differentially expressed genes (128 up-regulated and 485 down-regulated genes using cutoff |log2FC| < 1 and p < 0.05) in PBRM1 mutated group versus “pan-negative” group.

2. In addition, we identified 1405 differentially methylated CpG sites (targeting 1308 genes, |log2FC| < 1, p < 0.01) and 185 significantly altered microRNAs (|log2FC| < 1, p < 0.05) associated with truncated PBRM1 mutations.

In both sentences the present expression in the article is "|log2FC| < 1". However, this is incorrect, as the cutoff should be "|log2FC| > 1".

References

  1. 1.

    Wang Y, et al. An integrative genomics approach for identifying novel functional consequences of PBRM1 truncated mutations in clear cell renal cell carcinoma (ccRCC). BMC Genomics. 2016;17 Suppl 7:515.

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Author information

Affiliations

  1. Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA

    • Yuanyuan Wang
    • , Xingyi Guo
    •  & Zhongming Zhao

  2. Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA

    • Xingyi Guo

  3. Vanderbilt Genetics Institute, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA

    • Michael J. Bray

  4. Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA

    • Zhiyong Ding

  5. Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA

    • Zhongming Zhao

  6. Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, 37212, USA

    • Zhongming Zhao

  7. Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA

    • Zhongming Zhao

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Corresponding author

Correspondence to Zhongming Zhao.

Additional information

From The International Conference on Intelligent Biology and Medicine (ICIBM), Indianapolis, IN, USA. 13–15 November 2015

The online version of the original article can be found under doi:10.1186/s12864-016-2906-9.

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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BMC Genomics

ISSN: 1471-2164

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