Fig. 3

lncRNA microarray analyses of IBDV-infected chicken DCs. a Volcano plot map of lncRNA expression in control DCs and IBDV-infected DCs at 12 h post-infection. A comparison of expression data was performed using an XY-scatter plot analysis of the log base 2-fold change. Data points shown in red represent significant differentially expressed genes; P < 0.01. b Heat map of differentially expressed lncRNAs in IBDV-stimulated chicken DCs. All of the biological replicates were pooled and calculated to identify differentially expressed lncRNAs based on a threshold fold change > 2 and P < 0.01. c Potential interaction network among the significant differentially expressed lncRNAs (fold change > 2 and P < 0.01) and target genes with cytoscape (red represents co-expressed lncRNAs, whereas gray represents co-expressed mRNAs). d Primary GO categorisation based on target genes from differentially expressed miRNAs in IBDV-stimulated chicken DCs. e KEGG and BIOCARTA pathway analyses based on target genes from differentially expressed miRNAs in IBDV-stimulated chicken DCs