Fig. 10

Control Coefficients and Fluxes contrasting all Substrates. Comparisons of control coefficients (a, c, e) to predicted metabolic fluxes (b, d, f). (a, b) MeOH vs Acetate, (c, d) TMA vs Acetate, (e, f) MeOH vs TMA. Control coefficients (a, c, e) indicate that reactions are transcriptionally controlled (green), degradationally controlled (red) or shared control (blue). Mappings of predicted metabolic fluxes indicate higher flux in the second substrate (red) versus lower flux in the second substrate (blue). Larger versions of (a, b) can be seen in Figs. 5 and 8. Larger versions of (b-f) can be seen in Additional file 1: Figures S19, S20, S21, and S22. The names for each reaction and metabolite can be seen by zooming into the the larger versions of the maps in the Additional file