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Table 1 Demographics of Graves’ disease cases and controls in the discovery and replication cohorts

From: Pooled genome wide association detects association upstream of FCRL3 with Graves’ disease

 

N

Mean age (SD)

Sex

Case

Control

Case

Control

p value

Graves’ case

Controls

p value

Discovery cohort

412

498

45.3 (14.5)

56.3 (24.4)

<0.001

Male 71 (17.23 %)

Male 192 (41.03 %)

<0.001

Female 341 (82.77 %)

Female 276 (58.97 %)

Replication cohort

539

1230

44.5 (14.8)

48.1 (17.4)

<0.001

Male 109 (20.30 %)

Male 596 (49.30 %)

<0.001

Female 428 (79.70 %)

Female 613 (50.70 %)