From: Pooled genome wide association detects association upstream of FCRL3 with Graves’ disease
N | Mean age (SD) | Sex | ||||||
---|---|---|---|---|---|---|---|---|
Case | Control | Case | Control | p value | Graves’ case | Controls | p value | |
Discovery cohort | 412 | 498 | 45.3 (14.5) | 56.3 (24.4) | <0.001 | Male 71 (17.23 %) | Male 192 (41.03 %) | <0.001 |
Female 341 (82.77 %) | Female 276 (58.97 %) | |||||||
Replication cohort | 539 | 1230 | 44.5 (14.8) | 48.1 (17.4) | <0.001 | Male 109 (20.30 %) | Male 596 (49.30 %) | <0.001 |
Female 428 (79.70 %) | Female 613 (50.70 %) |