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Fig. 2 | BMC Genomics

Fig. 2

From: Short bowel syndrome results in increased gene expression associated with proliferation, inflammation, bile acid synthesis and immune system activation: RNA sequencing a zebrafish SBS model

Fig. 2

SBS zebrafish have increased expression of proliferation, inflammation and immunity. a-c Heat-maps of RNA-seq analysis show the gene expression differences between SBS and sham zebrafish in regards to cellular proliferation, acute phase response signaling and innate and adaptive immunity. RT-qPCR confirmation was performed on examples of cellular proliferation [igf2a (d), ccnb1 (cyclin B1, (e)), ccnd1 (cyclin D1, (f)), ctnnb1 (β-catenin, (g)), lef1 (h), wnt5a (i), dkk3 (j)], acute phase response signaling [saa1 (k), tnfa (l), stat3 (m)] and innate and adaptive immunity (il1b (n), ifng1-2 (o)]. * denotes p < 0.5, ** p < 0.1, *** p < 0.001

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