Table 2 Comparison of four selection criteria on GSE22220
From: A clustering-based approach for efficient identification of microRNA combinatorial biomarkers
Feature combination | Performance measure | Selection criteria | |||
|---|---|---|---|---|---|
| Â | Â | FDA | T-test | SNR | Centera |
Pair | AvgRank 10 | 7.6 | 8.2 | 96.7 | 112.2 |
| Â | AvgRank 100 | 82.9 | 84.4 | 412.3 | 557.5 |
| Â | AvgRank 1000 | 1586.5 | 1624.4 | 3248.7 | 3355.7 |
| Â | HitRatio 10(%) | 80.0 | 70.0 | 0 | 0 |
| Â | HitRatio 100(%) | 59.0 | 58.0 | 6.0 | 4.0 |
| Â | HitRatio 1000(%) | 33.0 | 32.0 | 16.0 | 11.0 |
Triple | AvgRank 10 | 9.9 | 8.6 | 333.1 | 333.3 |
| Â | AvgRank 100 | 93.4 | 94.4 | 2607.6 | 2270.7 |
| Â | AvgRank 1000 | 1612.2 | 1684.3 | 13833.3 | 14626.0 |
| Â | HitRatio 10(%) | 60.0 | 50.0 | 10.0 | 0 |
| Â | HitRatio 100(%) | 58.0 | 58.0 | 2.0 | 1.0 |
| Â | HitRatio 1000(%) | 28.0 | 27.1 | 1.3 | 1.5 |
Quadruple | AvgRank 10 | 12.8 | 12.8 | 41.7 | 744.9 |
| Â | AvgRank 100 | 115.4 | 108.5 | 408.2 | 4938.1 |
| Â | AvgRank 1000 | 1482.3 | 1562.6 | 10491.6 | 39605.2 |
| Â | HitRatio 10(%) | 40.0 | 40.0 | 50.0 | 0 |
| Â | HitRatio 100(%) | 50.0 | 45.0 | 24.0 | 0 |
| Â | HitRatio 1000(%) | 26.2 | 24.4 | 8.4 | 0.5 |