Table 2 Top 30 of genes with the highest or least changes in mRNA abundance in spleen (A) and lung (B). The scanned region for promotor elements ranged from 6 kb upstream to 1 kb downstream of the first exon

PTX3

Pentraxin related gene, rapidly induced by IL1 beta

685

3 h

x

x

0/7

SFTPA1

Surfactant, pulmonary-associated protein A1

−436

9 h

x

-

0/12

LOC396260

Mature avidin

384

9 h

-

x

1/7

IL6

Interleukin-6

186

3 h

x

x

0/8

LAO

L-amino-acid oxidase precursor (Interleukin-4 induced 1)

169

3 h

-

x

0/7

K203

Chicken chemokine (C-C motif) L i 3

145

3 h

-

x

0/6

LL

Lung lectin

−140

9 h

-

-

0/12

PSCA

Prostate stem cell antigen

−124

9 h

-

-

0/12

KCNA1

Potassium voltage-gated channel, shaker-related subfamily, member 1

−69

3 h

-

-

0/5

LYG2

Lysozyme G-like 2

62

3 h

-

x

0/6

CSF3

Colony stimulating factor 3

58

3 h

x

x

0/3

NEFH

Neurofilament, heavy polypeptide

−56

3 h

-

-

0/5

CMBL

Carboxymethylenebutenolidase homolog

44

3 h

-

x

0/12

GCH1

GTP cyclohydrolase 1

43

3 h

x

x

0/9

FSHR

Follicle stimulating hormone receptor

−39

3 h

-

-

0/5

ZPD

Zona pellucida protein D

38

3 h

-

-

0/13

IRG1

Immunoresponsive 1 homolog

35

3 h

-

x

0/9

BATF3

Basic leucine zipper transcription factor, ATF-like 3

35

3 h

-

x

0/11

IL22

Interleukin-22

34

3 h

x

x

0/4

MAOA

Monoamine oxidase A

33

9 h

-

x

0/11

HPS5

Hermansky Pudlak syndrome 5

30

6 h

x

x

0/10

ETV1

ETS variant gene 1

−30

3 h

-

-

0/13

TULP1

Tubby like protein 1

28

3 h

-

x

0/11

MMP1

Matrix metallopeptidase 1 (interstitial collagenase)

27

3 h

-

x

1/7

LIPI

Lipase, member I

26

3 h

-

x

1/9

RPL37

Ribosomal protein L37

26

3 h

x

x

0/9

GBP

Guanylate binding protein

25

3 h

x

x

0/5

OAS

2‘5’oligoadenylate synthetase like

25

3 h

x

x

0/0

SPINK5

Serine peptidase inhibitor, Kazal type 5

−25

6 h

-

-

0/7

Mx1

Myxovirus (influenza virus) resistance-1

24

3 h

x

x

1/16

TULP1

Tubby like protein 1

118

3 h

-

x

0/11

IL6

Interleukin-6

67

9 h

x

x

0/8

CMBL

Carboxymethylenebutenolidase homolog

53

3 h

-

x

0/12

LOC396260

Mature avidin

44

9 h

-

x

1/7

LAO

L-amino-acid oxidase precursor

40

3 h

-

x

0/7

MSC

Musculin (activated B-cell factor-1)

33

3 h

-

x

0/5

FKBP5

FK506 binding protein 5

30

3 h

x

x

0/6

TGM4

Transglutaminase 4 (prostate)

24

3 h

-

-

0/10

LYG2

Lysozyme G-like 2

24

3 h

-

x

0/6

BATF3

Basic leucine zipper transcription factor, ATF-like 3

22

3 h

-

x

0/11

GBP

Guanylate binding protein

22

3 h

x

x

0/5

RPL37

Ribosomal protein L37

20

3 + 9 h

x

x

0/9

IFIT-5

Interferon induced protein with tetratricopeptide repeats 5

18

3 + 9 h

x

x

1/9

IRG1

Immunoresponsive 1 homolog

19

9 h

-

x

0/9

TLR5

Toll-like receptor-5

−18

3 h

x

-

0/11

SEMA6D

−17

3 h

-

x

0/11

GCH1

GTP cyclohydrolase 1

17

3 h

x

x

0/9

GAL9

Gallicin 9

16

3 h

-

-

0/8

Rd

Riboflavin-binding protein

16

3 h

-

-

0/15

MAOA

Monoamine oxidase A

16

9 h

-

x

0/11

SAMD9L

Sterile alpha motif domain containing 9 like

15

3 + 9 h

x

x

0/13

K203

Chicken chemokine (C-C motif) L i 3

14

9 h

-

x

0/6

IL1RL1

Interleukin-1 receptor like 1

14

3 h

x

x

0/15

MX1

Myxovirus (influenza virus) resistance-1

13

3 + 6 + 9 h

x

x

1/16

SOCS3

Suppressor of cytokine signaling 3

12

9 h

x

x

1/9

RASD1

RAS, dexamethasone induced 1

12

3 h

-

x

0/3

OAS

2‘5’oligoadenylate synthetase like protein

11

3 h

x

x

0/0

ALB

Albumin

10

3 h

-

-

0/12

PDK4

Pyruvate dehydrogenase kinase, isozyme 4

10

3 h

x

x

0/12

SNAP25

Synaptosomal-associated protein, 25 kDa

−10

3 h

x

-

0/19