Table 3 Expression profiles of genes involved in testicular differentiation and spermatogenesis. 40CO, 40 dpf control ovaries. 40CT, 40 dpf control testes. 60CO, 60 dpf control ovaries. 60CT, 60 dpf control testes
From: Histological and transcriptomic effects of 17α-methyltestosterone on zebrafish gonad development
No. | Gene name | Gene ID | Fold change for control gonads | |
|---|---|---|---|---|
Testis-Enriched Genes | 40CT/40CO | 60CT/60CO | ||
Male sex determination | ||||
1 | amh | 129.92 | 72.07 | |
2 | dmrt1 | NM_205628 | 13.89 | 23.43 |
3 | gsdf | NM_001114668 | 141.09 | 69.01 |
Sertoli cell differentiation | ||||
4 | gata4 | 4.31 | n.s. | |
5 | sox9a | 4.27 | 3.56 | |
Leydig cell differentiation | ||||
6 | pdgfra | 2.81 | n.s. | |
Steroidogenesis | ||||
7 | ar | 3.38 | n.s. | |
8 | cyp11c1 | 40.77 | 61.48 | |
9 | cyp17a1 | 4.84 | 2.63 | |
10 | esr2b | 11.38 | 7.92 | |
11 | hsd11b2 | 32.13 | 19.24 | |
12 | nr5a1a | NM_131794 | 5.17 | 4.05 |
13 | star | 70.58 | 117.91 | |
GABA and dopamine signalling | ||||
14 | gabrr2b | XM_692394.7 | 8.25 | 23.26 |
15 | drd2l | NM_197935.1 | n.s. | 2.46 |
Spermiogenesis | ||||
16 | klhl10a | XM_002665116 | n.s. | 16.97 |
17 | odf3b | n.s. | 16.38 | |
18 | tekt1 | NM_001007397 | 25.00 | 177.52 |
Septin signalling | ||||
19 | sept3 | NM_001024418 | n.s. | 6.14 |
20 | sept8b | NM_001083566 | n.s. | 8.13 |
Histone variants | ||||
21 | h1f0 | NM_199552.1 | 61.83 | 258.58 |
22 | h1fx | NM_199276.1 | 16.43 | 25.91 |
23 | h2afy2 | NM_001025502.1 | 14.10 | 21.92 |
24 | histh1l | NM_001017660.2 | 10.67 | 10.43 |
25 | hist2h2l | NM_200117.1 | 5.78 | 7.30 |
Immune response | ||||
26 | mif | NM_001043321.1 | 2.32 | 2.42 |
27 | il1b | NM_212844.2 | 2.38 | 4.23 |
28 | irf9 | NM_205710.2 | 4.29 | 4.34 |
Others | ||||
29 | dkk3b | NM_001089545 | 9.03 | 2.67 |
30 | tp53 | 2.55 | n.s. | |