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Table 4 The 25 most highly expressed genes in Mytilisepta virgata foot and representative significantly over-represented annotations by gene set enrichment analysis

From: The purplish bifurcate mussel Mytilisepta virgata gene expression atlas reveals a remarkable tissue functional specialization

Most expressed genes

Over-represented annotations

Annotation

TPM

Term

Class

p-value

Byssal cuticle protein

45,262.97

Collagen triple helix repeat (20 copies)

PFAM

0.00

Byssal cuticle protein

43,379.14

Serine-type endopeptidase inhibitor activity

MF

0.00

Collagen-like protein

42,699.96

Negative regulation of coagulation

BP

1.11E-16

Byssal cuticle protein

34,293.81

Common central domain of tyrosinase

PFAM

3.33E-16

Collagen-like protein

33,886.43

Extracellular region

CC

3.33E-16

Serine protease inhibitor

30,056.14

Negative regulation of endopeptidase activity

BP

6.77E-15

Low complexity protein

26,250.15

Animal haem peroxidase

PFAM

6.77E-14

Collagen-like protein

17,017.56

Kazal-type serine protease inhibitor domain

PFAM

4.35E-12

YGH-rich protein-2

16,065.78

Peroxidase activity

MF

5.69E-12

Collagen-like protein

15,351.63

Proteinaceous extracellular matrix

CC

6.47E-12

Collagen-like protein

13,389.57

Tissue inhibitor of metalloproteinase

PFAM

6.83E-10

Byssal cuticle protein

12,178.71

Collagen trimer

CC

2.14E-8

Collagen-like protein

10,965.75

Response to oxidative stress

BP

5.45E-8

Elongation factor 1 alpha

10,722.32

Regulation of keratinocyte differentiation

BP

8.93E-8

Collagen-like protein

10,461.88

Hydrogen peroxide catabolic process

BP

1.05E-7

YGH-rich protein-1

10,019.89

Transforming growth factor beta binding

MF

1.63E-7

Precollagen NG

9810.75

Metal ion binding

MF

8.77E-7

YGH-rich protein-1

8119.26

Extracellular space

CC

9.20E-7

Serine protease inhibitor

7406.30

Heme binding

MF

2.55E-6

Serine protease inhibitor

7362.32

Oxidoreductase activity

MF

6.45E-6

Collagen-like protein

7349.68

WAP-type ‘four-disulfide core’

PFAM

1.01E-5

Collagen-like protein

7307.02

Quinone binding

MF

1.26E-5

Unknown

7104.95

Human growth factor-like EGF

PFAM

1.78E-5

Kazal-type serine proteinase inhibitor

7095.67

EGF-like domain

PFAM

6.84E-5

Low complexity protein

6445.09

Kunitz/Bovine pancreatic trypsin inhibitor domain

PFAM

7.62E-5

  1. See the complete list in Additional file 4
  2. TPM Transcript Per Million, PFAM Pfam conserved domains, BP Gene Ontology Biological Process, MF Gene Ontology Molecular Function, CC Gene Ontology Cellular Component