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Table 2 List of proteins that are differentially expressed in skin mucus of S. aurata after chronic wounds

From: Chronic wounds alter the proteome profile in skin mucus of farmed gilthead seabream

Spot

Protein name

Fold change

Previously detected in skin mucus?

References

H1

Histone H4 (H4)

↓ 0.01

Yes

[21, 23]

H2

Apolipoprotein A1 (APOA1)

↓ 0.04

Yes

[19,20,21,22, 29, 40]

H3

Histone H2B (H2B)

↓ 0.12

Yes

[20]

H4

Cu/Zn Superoxide dismutase (SOD)

↓ 0.09

Yes

[21,22,23]

H5

Histone H2A (H2A)

↓ 0.06

Yes

[23]

H6

14–3-3 protein beta/alpha 1

↓ 0.02

Yes

[19,20,21,22,23, 29]

H7

Apolipoprotein A1 (APOA1)

↓ 0.44

Yes

[19,20,21,22, 29]

H8

Phosphatidylethanolamine-binding protein 1 (PEBP1)

↓ 0.09

Yes

[22, 23]

H9

Apolipoprotein A1 (APOA1)

↓ 0.06

Yes

[19,20,21,22, 29, 40]

H10

Actin cytoplasmic 1 (ACTB)

↓ 0.32

Yes

[20,21,22,23, 29, 40]

H11

Natural killer enhancing factor 2 (NKEF2)

↓ 0.13

Yes

[21,22,23]

H12

ADP-ribosylation factor 3 (ARF3)

↓ 0.06

Yes

[29, 40]

H13

Natural killer enhancing factor 1 (NKEF1)

↓ 0.17

Yes

[20,21,22,23]

H14

Glutathione S-transferase 3 (GST3)

↓ 0.11

No

None

H15

Triosephosphate isomerase A (TPIA)

↓ 0.01

Yes

[19, 23, 29]

H16

Triosephosphate isomerase B (TPIB)

↓ 0.02

Yes

[19, 21, 23]

H17

Triosephosphate isomerase B (TPIB)

↓ 0.01

Yes

[19, 21, 23]

H18

ATP synthase subunit beta (ATB5B)

↓ 0.07

Yes

[20, 22, 23, 40]

H19

Actin-related protein (ARP)

↓ 0.46

Yes

[23, 24, 40]

H20

Actin cytoplasmic 1 (ACTB)

↓ 0.25

Yes

[19, 21,22,23, 40]

H21

Macrophage-capping protein (CAPG)

↓ 0.18

Yes

[22]

H22

Citrate synthase (CS)

↓ 0.09

Yes

[19]

H23

Heat shock cognate 71 kDa (HSC70)

↓ 0.12

Yes

[20, 22, 23, 40]

H24

Heat shock cognate 71 kDa (HSC70)

↓ 0.27

Yes

[20, 22, 23, 40]

H25

Keratin type I (KRT1)

↓ 0.11

Yes

[19,20,21,22,23, 29]

H26

Complement component 3 (C3)

↓ 0.36

Yes

[21, 29, 40]

H27

Gelsolin (GSN)

↓ 0.41

Yes

[21, 22, 40]

H28

Immunoglobulin M heavy chain (IgM)

↓ 0.07

No

None

  1. ↓ indicates under-expression of the proteins at p < 0.01. In addition, a literature-based comparison about presence of these proteins in skin mucus of other fish species after 2-DE spot detection is included