Fig. 7
From: Transcriptome analysis of Xenopus orofacial tissues deficient in retinoic acid receptor function
Overlap of altered gene expression in RAR deficient face and human orofacial defects. Venn diagram exhibiting the overlap among genes altered in our treatment paradigm in Xenopus and human median orofacial defects. Blue circle: total number of Xenopus genes with human orthologs (415) that were significantly altered with early RAR inhibition. Green circle: total number of Xenopus genes with human orthologs (93) that were significantly altered with late RAR inhibition. Grey circle: Human genes associated with one of the six craniofacial defects listed (325 total). Overlap of circles denotes genes that appeared in both lists