Down-regulated | Up-regulated | ||||
---|---|---|---|---|---|
GO | Term | P-value | GO | Term | P-value |
GO:0004672 | protein kinase activity | 1.20E-08 | GO:0016491 | oxidoreductase activity | 4.10E-07 |
GO:0030246 | carbohydrate binding | 7.00E-07 | GO:0020037 | heme binding | 7.50E-07 |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 8.30E-07 | GO:0046906 | tetrapyrrole binding | 8.80E-07 |
GO:0016740 | transferase activity | 1.10E-06 | GO:0016705 | oxidoreductase activity, acting on paired donors | 9.60E-07 |
GO:0016301 | kinase activity | 1.10E-06 | GO:0048037 | cofactor binding | 4.80E-06 |
GO:0140096 | catalytic activity, acting on a protein | 4.60E-06 | GO:0005506 | iron ion binding | 1.20E-05 |
GO:0005516 | calmodulin binding | 1.40E-05 | GO:0015035 | protein disulfide oxidoreductase activity | 0.00015 |
GO:0016772 | transferase activity, transferring phosphorus-containing groups | 0.00012 | GO:0003824 | catalytic activity | 0.00015 |
GO:0003824 | catalytic activity | 0.00024 | GO:0015036 | disulfide oxidoreductase activity | 0.0002 |
GO:0016758 | transferase activity, transferring hexosyl groups | 0.00167 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors | 0.00049 |
GO:0016872 | intramolecular lyase activity | 0.00218 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | 0.00116 |
GO:0005524 | ATP binding | 0.00244 | GO:0009055 | electron transfer activity | 0.00171 |
GO:0001871 | pattern binding | 0.00295 | GO:0016798 | hydrolase activity, acting on glycosyl bonds | 0.00199 |
GO:0030247 | polysaccharide binding | 0.00295 | GO:0046872 | metal ion binding | 0.00348 |
GO:0004970 | ionotropic glutamate receptor activity | 0.00346 | GO:0043169 | cation binding | 0.00378 |
GO:0005230 | extracellular ligand-gated ion channel activity | 0.00346 | GO:0046914 | transition metal ion binding | 0.00404 |
GO:0008066 | glutamate receptor activity | 0.00346 | GO:0016161 | beta-amylase activity | 0.00435 |
GO:0015276 | ligand-gated ion channel activity | 0.00346 | GO:0019139 | cytokinin dehydrogenase activity | 0.00511 |
GO:0022824 | transmitter-gated ion channel activity | 0.00346 | GO:0008236 | serine-type peptidase activity | 0.0078 |
GO:0022834 | ligand-gated channel activity | 0.00346 | GO:0017171 | serine hydrolase activity | 0.0078 |
GO:0022835 | transmitter-gated channel activity | 0.00346 | GO:0016160 | amylase activity | 0.00975 |
GO:0030594 | neurotransmitter receptor activity | 0.00346 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity | 0.01198 |
GO:0008144 | drug binding | 0.00371 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity | 0.01198 |
GO:0016757 | transferase activity, transferring glycosyl groups | 0.00415 | GO:0017048 | Rho GTPase binding | 0.01198 |
GO:0008429 | phosphatidylethanolamine binding | 0.0049 | GO:0016702 | oxidoreductase activity, acting on single donors | 0.01388 |
GO:0004888 | transmembrane signaling receptor activity | 0.00504 | GO:0070011 | peptidase activity, acting on L-amino acid peptides | 0.0141 |
GO:0038023 | signaling receptor activity | 0.00504 | GO:0008233 | peptidase activity | 0.01719 |
GO:0060089 | molecular transducer activity | 0.00504 | GO:0051213 | dioxygenase activity | 0.01937 |
GO:0032559 | adenyl ribonucleotide binding | 0.00585 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor | 0.0213 |
GO:0030554 | adenyl nucleotide binding | 0.00633 | GO:0004455 | ketol-acid reductoisomerase activity | 0.0249 |
GO:0043565 | sequence-specific DNA binding | 0.00742 | GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors | 0.02597 |
GO:0016705 | oxidoreductase activity, acting on paired donors | 0.01055 | GO:0016701 | oxidoreductase activity, acting on single donors with oxygen | 0.0277 |
GO:0035639 | purine ribonucleoside triphosphate binding | 0.01262 | GO:0016787 | hydrolase activity | 0.03003 |
GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups | 0.01586 | GO:0005085 | guanyl-nucleotide exchange factor activity | 0.04019 |
GO:0022839 | ion gated channel activity | 0.01729 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity | 0.04116 |
GO:0022857 | transmembrane transporter activity | 0.02096 | GO:0004749 | ribose phosphate diphosphokinase activity | 0.04116 |
GO:0032555 | purine ribonucleotide binding | 0.02266 | GO:0005092 | GDP-dissociation inhibitor activity | 0.04919 |
GO:0022836 | gated channel activity | 0.02311 | GO:0005094 | Rho GDP-dissociation inhibitor activity | 0.04919 |
GO:0005216 | ion channel activity | 0.02628 | GO:0016778 | diphosphotransferase activity | 0.04919 |
GO:0022838 | substrate-specific channel activity | 0.02628 | Â | Â | Â |
GO:0032553 | ribonucleotide binding | 0.0265 | Â | Â | Â |
GO:0017076 | purine nucleotide binding | 0.02712 | Â | Â | Â |
GO:0015267 | channel activity | 0.03204 | Â | Â | Â |
GO:0022803 | passive transmembrane transporter activity | 0.03204 | Â | Â | Â |
GO:0050664 | oxidoreductase activity, acting on NAD(P) H, oxygen as acceptor | 0.0339 | Â | Â | Â |
GO:0097367 | carbohydrate derivative binding | 0.03397 | Â | Â | Â |
GO:0043168 | anion binding | 0.03531 | Â | Â | Â |
GO:0005506 | iron ion binding | 0.03867 | Â | Â | Â |
GO:0020037 | heme binding | 0.04013 | Â | Â | Â |
GO:0022804 | active transmembrane transporter activity | 0.0407 | Â | Â | Â |
GO:0000166 | nucleotide binding | 0.0408 | Â | Â | Â |
GO:1901265 | nucleoside phosphate binding | 0.0408 | Â | Â | Â |
GO:0016651 | oxidoreductase activity, acting on NAD(P)H | 0.0412 | Â | Â | Â |
GO:0005215 | transporter activity | 0.04162 | Â | Â | Â |
GO:0046906 | tetrapyrrole binding | 0.04373 | Â | Â | Â |
GO:0030410 | nicotianamine synthase activity | 0.04483 | Â | Â | Â |
GO:0005342 | organic acid transmembrane transporter activity | 0.04757 | Â | Â | Â |
GO:0015171 | amino acid transmembrane transporter activity | 0.04757 | Â | Â | Â |
GO:0046943 | carboxylic acid transmembrane transporter activity | 0.04757 | Â | Â | Â |