Fig. 2

Survival rate and body weight of the infected wild-type (WT) and CCR5-deficient (KO) mice. a Survival rate was monitored until 30 dpi (infected WT, n = 10 + 8; infected CCR5KO, n = 9 + 6). Survival rate was compared between groups using the log-rank test (*p < 0.05). b Body weight change was monitored until 9 dpi, the day before the infected group started to die (uninfected WT, n = 4; uninfected CCR5KO, n = 4; infected WT, n = 10; infected CCR5KO, n = 9). Each point represents the mean ± SD. The weight difference between 0 dpi and 9 dpi was compared using two-way ANOVA. Effect of infection on body weight was significant (*p < 0.0001) but not the mouse genotype or the interaction between infection and mouse genotype (p > 0.05)