Lincke A, Drillich M, Heuwieser W. Subclinical endometritis in dairy cattle and its effect on fertility--a review of recent publications. Berl Munch Tierarztl Wochenschr. 2007;120(5–6):245–50.
PubMed
Google Scholar
Sheldon IM, Cronin J, Goetze L, Donofrio G, Schuberth HJ. Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle. Biol Reprod. 2009;81(6):1025–32.
Article
CAS
PubMed
Google Scholar
Gilbert RO. The effects of endometritis on the establishment of pregnancy in cattle. Reprod Fertil Dev. 2011;24(1):252–7.
Article
CAS
PubMed
Google Scholar
Graham MR, Bowdridge EC, Bowdridge SA, Holásková I, Elsasser TH, Dailey RA. Effect of lipopolysaccharide-induced immune responses on pregnancy loss in ewes. Open J Anim Sci. 2018;08(04):421–31.
Article
CAS
Google Scholar
Cronin JG, Turner ML, Goetze L, Bryant CE, Sheldon IM. Toll-like receptor 4 and MYD88-dependent signaling mechanisms of the innate immune system are essential for the response to lipopolysaccharide by epithelial and stromal cells of the bovine endometrium. Biol Reprod. 2012;86(2):51.
Article
PubMed
CAS
Google Scholar
Herath S, Fischer DP, Werling D, Williams EJ, Lilly ST, Dobson H, Bryant CE, Sheldon IM. Expression and function of toll-like receptor 4 in the endometrial cells of the uterus. Endocrinology. 2006;147(1):562–70.
Article
CAS
PubMed
Google Scholar
Cronin JG, Kanamarlapudi V, Thornton CA, Sheldon IM. Signal transducer and activator of transcription-3 licenses toll-like receptor 4-dependent interleukin (IL)-6 and IL-8 production via IL-6 receptor-positive feedback in endometrial cells. Mucosal Immunol. 2016;9(5):1125–36.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sheldon IM, Roberts MH. Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium. PLoS One. 2010;5(9):e12906.
Article
PubMed
PubMed Central
CAS
Google Scholar
Robertson SA, Moldenhauer LM. Immunological determinants of implantation success. Int J Dev Biol. 2014;58(2–4):205–17.
Article
CAS
PubMed
Google Scholar
Guo Y, Chankeaw W, Chanrot M, Valarcher J, Chantarapratep P, Bage R, Bongcam-Rudloff E, Andersson G, Charpigny G, Humblot P. Changes induced by pathogens and metabolic stress on endometrial function in cattle: possible impacts of increased inflammation on fertility. Rev Bras Reprod Anim. 2019;43(n2):295–307.
Google Scholar
Walker CG, Littlejohn MD, Meier S, Roche JR, Mitchell MD. DNA methylation is correlated with gene expression during early pregnancy in Bos taurus. Physiol Genomics. 2013;45(7):276–86.
Article
CAS
PubMed
Google Scholar
Furst RW, Meyer HH, Schweizer G, Ulbrich SE. Is DNA methylation an epigenetic contribution to transcriptional regulation of the bovine endometrium during the estrous cycle and early pregnancy? Mol Cell Endocrinol. 2012;348(1):67–77.
Article
PubMed
CAS
Google Scholar
Logan PC, Ponnampalam AP, Rahnama F, Lobie PE, Mitchell MD. The effect of DNA methylation inhibitor 5-Aza-2′-deoxycytidine on human endometrial stromal cells. Hum Reprod. 2010;25(11):2859–69.
Article
CAS
PubMed
Google Scholar
Jha RK, Titus S, Saxena D, Kumar PG, Laloraya M. Profiling of E-cadherin, beta-catenin and Ca (2+) in embryo-uterine interactions at implantation. FEBS Lett. 2006;580(24):5653–60.
Article
CAS
PubMed
Google Scholar
Li Q, Wang J, Armant DR, Bagchi MK, Bagchi IC. Calcitonin down-regulates E-cadherin expression in rodent uterine epithelium during implantation. J Biol Chem. 2002;277(48):46447–55.
Article
CAS
PubMed
Google Scholar
Liu G, Zhang X, Lin H, Wang H, Li Q, Ni J, Zhu C. Effects of E-cadherin on mouse embryo implantation and expression of matrix metalloproteinase-2 and -9. Biochem Biophys Res Commun. 2006;343(3):832–8.
Article
CAS
PubMed
Google Scholar
Matsuzaki S, Darcha C, Maleysson E, Canis M, Mage G. Impaired down-regulation of E-cadherin and beta-catenin protein expression in endometrial epithelial cells in the mid-secretory endometrium of infertile patients with endometriosis. J Clin Endocrinol Metab. 2010;95(7):3437–45.
Article
CAS
PubMed
Google Scholar
Rahnama F, Thompson B, Steiner M, Shafiei F, Lobie PE, Mitchell MD. Epigenetic regulation of E-cadherin controls endometrial receptivity. Endocrinology. 2009;150(3):1466–72.
Article
CAS
PubMed
Google Scholar
Wu Y, Halverson G, Basir Z, Strawn E, Yan P, Guo SW. Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis. Am J Obstet Gynecol. 2005;193(2):371–80.
Article
CAS
PubMed
Google Scholar
Novakovic B, Habibi E, Wang SY, Arts RJW, Davar R, Megchelenbrink W, Kim B, Kuznetsova T, Kox M, Zwaag J, et al. beta-Glucan reverses the epigenetic state of LPS-induced immunological tolerance. Cell. 2016;167(5):1354–68 e1314.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sheldon IM, Price SB, Cronin J, Gilbert RO, Gadsby JE. Mechanisms of infertility associated with clinical and subclinical endometritis in high producing dairy cattle. Reprod Domest Anim. 2009;44(Suppl 3):1–9.
Article
PubMed
Google Scholar
Singh J, Murray RD, Mshelia G, Woldehiwet Z. The immune status of the bovine uterus during the peripartum period. Vet J. 2008;175(3):301–9.
Article
CAS
PubMed
Google Scholar
LeBlanc SJ. Interactions of metabolism, inflammation, and reproductive tract health in the postpartum period in dairy cattle. Reprod Domest Anim. 2012;47(Suppl 5):18–30.
Article
PubMed
Google Scholar
Walker CG, Littlejohn MD, Mitchell MD, Roche JR, Meier S. Endometrial gene expression during early pregnancy differs between fertile and subfertile dairy cow strains. Physiol Genomics. 2012;44(1):47–58.
Article
CAS
PubMed
Google Scholar
Walker CG, Meier S, Hussein H, McDougall S, Burke CR, Roche JR, Mitchell MD. Modulation of the immune system during postpartum uterine inflammation. Physiol Genomics. 2015;47(4):89–101.
Article
CAS
PubMed
Google Scholar
Walker CG, Meier S, Littlejohn MD, Lehnert K, Roche JR, Mitchell MD. Modulation of the maternal immune system by the pre-implantation embryo. BMC Genomics. 2010;11:474.
Article
PubMed
PubMed Central
CAS
Google Scholar
Wang J, Yan X, Nesengani LT, Ding H, Yang L, Lu W. LPS-induces IL-6 and IL-8 gene expression in bovine endometrial cells "through DNA methylation". Gene. 2018;677:266–72.
Article
CAS
PubMed
Google Scholar
Guo Y, van Schaik T, Jhamat N, Niazi A, Chanrot M, Charpigny G, Valarcher JF, Bongcam-Rudloff E, Andersson G, Humblot P. Differential gene expression in bovine endometrial epithelial cells after challenge with LPS; specific implications for genes involved in embryo maternal interactions. PLoS One. 2019;14(9):e0222081.
Article
CAS
PubMed
PubMed Central
Google Scholar
Dohmen MJ, Joop K, Sturk A, Bols PE, Lohuis JA. Relationship between intra-uterine bacterial contamination, endotoxin levels and the development of endometritis in postpartum cows with dystocia or retained placenta. Theriogenology. 2000;54(7):1019–32.
Article
CAS
PubMed
Google Scholar
Williams EJ, Fischer DP, Noakes DE, England GC, Rycroft A, Dobson H, Sheldon IM. The relationship between uterine pathogen growth density and ovarian function in the postpartum dairy cow. Theriogenology. 2007;68(4):549–59.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chanrot M, Guo Y, Dalin AM, Persson E, Bage R, Svensson A, Gustafsson H, Humblot P. Dose related effects of LPS on endometrial epithelial cell populations from dioestrus cows. Anim Reprod Sci. 2017;177:12–24.
Article
CAS
PubMed
Google Scholar
Piras C, Guo Y, Soggiu A, Chanrot M, Greco V, Urbani A, Charpigny G, Bonizzi L, Roncada P, Humblot P. Changes in protein expression profiles in bovine endometrial epithelial cells exposed to E. coli LPS challenge. Mol BioSyst. 2017;13(2):392–405.
Article
CAS
PubMed
Google Scholar
Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009;4(1):44–57.
Article
PubMed
CAS
Google Scholar
Huang da W, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 2009;37(1):1–13.
Article
PubMed
CAS
Google Scholar
Houshdaran S, Zelenko Z, Irwin JC, Giudice LC. Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation. Mol Endocrinol. 2014;28(7):1118–35.
Article
PubMed
PubMed Central
CAS
Google Scholar
Saare M, Modhukur V, Suhorutshenko M, Rajashekar B, Rekker K, Soritsa D, Karro H, Soplepmann P, Soritsa A, Lindgren CM, et al. The influence of menstrual cycle and endometriosis on endometrial methylome. Clin Epigenetics. 2016;8:2.
Article
PubMed
PubMed Central
CAS
Google Scholar
Mortlock S, Restuadi R, Levien R, Girling JE, Holdsworth-Carson SJ, Healey M, Zhu Z, Qi T, Wu Y, Lukowski SW, et al. Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases. Clin Epigenetics. 2019;11(1):49.
Article
PubMed
PubMed Central
CAS
Google Scholar
Chen J, Wu Y, Sun Y, Dong X, Wang Z, Zhang Z, Xiao Y, Dong G. Bacterial Lipopolysaccharide Induced Alterations of Genome-Wide DNA Methylation and Promoter Methylation of Lactation-Related Genes in Bovine Mammary Epithelial Cells. Toxins (Basel). 2019;11(5). https://doi.org/10.3390/toxins11050298.
Korkmaz FT, Kerr DE. Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS. BMC Genomics. 2017;18(1):405.
Article
PubMed
PubMed Central
CAS
Google Scholar
Engdahl E, Dunn N, Niehusmann P, Wideman S, Wipfler P, Becker AJ, Ekstrom TJ, Almgren M, Fogdell-Hahn A. Human Herpesvirus 6B Induces Hypomethylation on Chromosome 17p13.3, Correlating with Increased Gene Expression and Virus Integration. J Virol. 2017;91(11). https://doi.org/10.1128/JVI.02105-16.
Macnab JC, Adams RL, Rinaldi A, Orr A, Clark L. Hypomethylation of host cell DNA synthesized after infection or transformation of cells by herpes simplex virus. Mol Cell Biol. 1988;8(4):1443–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pacis A, Tailleux L, Morin AM, Lambourne J, MacIsaac JL, Yotova V, Dumaine A, Danckaert A, Luca F, Grenier JC, et al. Bacterial infection remodels the DNA methylation landscape of human dendritic cells. Genome Res. 2015;25(12):1801–11.
Article
CAS
PubMed
PubMed Central
Google Scholar
Blasco MA. The epigenetic regulation of mammalian telomeres. Nat Rev Genet. 2007;8(4):299–309.
Article
CAS
PubMed
Google Scholar
Gadalla SM, Katki HA, Shebl FM, Giri N, Alter BP, Savage SA. The relationship between DNA methylation and telomere length in dyskeratosis congenita. Aging Cell. 2012;11(1):24–8.
Article
CAS
PubMed
Google Scholar
Maekawa R, Yagi S, Ohgane J, Yamagata Y, Asada H, Tamura I, Sugino N, Shiota K. Disease-dependent differently methylated regions (D-DMRs) of DNA are enriched on the X chromosome in uterine leiomyoma. J Reprod Dev. 2011;57(5):604–12.
Article
CAS
PubMed
Google Scholar
Kawakami T, Zhang C, Taniguchi T, Kim CJ, Okada Y, Sugihara H, Hattori T, Reeve AE, Ogawa O, Okamoto K. Characterization of loss-of-inactive X in Klinefelter syndrome and female-derived cancer cells. Oncogene. 2004;23(36):6163–9.
Article
CAS
PubMed
Google Scholar
Sirchia SM, Ramoscelli L, Grati FR, Barbera F, Coradini D, Rossella F, Porta G, Lesma E, Ruggeri A, Radice P, et al. Loss of the inactive X chromosome and replication of the active X in BRCA1-defective and wild-type breast cancer cells. Cancer Res. 2005;65(6):2139–46.
Article
CAS
PubMed
Google Scholar
Li L, Yang XJ. Molecular and functional characterization of histone Deacetylase 4 (HDAC4). Methods Mol Biol. 2016;1436:31–45.
Article
CAS
PubMed
Google Scholar
Kaowinn S, Jun SW, Kim CS, Shin DM, Hwang YH, Kim K, Shin B, Kaewpiboon C, Jeong HH, Koh SS, et al. Increased EGFR expression induced by a novel oncogene, CUG2, confers resistance to doxorubicin through Stat1-HDAC4 signaling. Cell Oncol (Dordr). 2017;40(6):549–61.
Article
CAS
Google Scholar
Sun Y, Qin B. Long noncoding RNA MALAT1 regulates HDAC4-mediated proliferation and apoptosis via decoying of miR-140-5p in osteosarcoma cells. Cancer Med. 2018;7(9):4584–97.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cai JY, Xu TT, Wang Y, Chang JJ, Li J, Chen XY, Chen X, Yin YF, Ni XJ. Histone deacetylase HDAC4 promotes the proliferation and invasion of glioma cells. Int J Oncol. 2018;53(6):2758–68.
CAS
PubMed
Google Scholar
Marroncelli N, Bianchi M, Bertin M, Consalvi S, Saccone V, De Bardi M, Puri PL, Palacios D, Adamo S, Moresi V. HDAC4 regulates satellite cell proliferation and differentiation by targeting P21 and Sharp1 genes. Sci Rep. 2018;8(1):3448.
Article
PubMed
PubMed Central
CAS
Google Scholar
Fan X, Krieg S, Hwang JY, Dhal S, Kuo CJ, Lasley BL, Brenner RM, Nayak NR. Dynamic regulation of Wnt7a expression in the primate endometrium: implications for postmenstrual regeneration and secretory transformation. Endocrinology. 2012;153(3):1063–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Liu Y, Meng F, Xu Y, Yang S, Xiao M, Chen X, Lou G. Overexpression of Wnt7a is associated with tumor progression and unfavorable prognosis in endometrial cancer. Int J Gynecol Cancer. 2013;23(2):304–11.
Article
PubMed
Google Scholar
Ingaramo PI, Milesi MM, Schimpf MG, Ramos JG, Vigezzi L, Munoz-de-Toro M, Luque EH, Varayoud J. Endosulfan affects uterine development and functional differentiation by disrupting Wnt7a and beta-catenin expression in rats. Mol Cell Endocrinol. 2016;425:37–47.
Article
CAS
PubMed
Google Scholar
Pazhohan A, Amidi F, Akbari-Asbagh F, Seyedrezazadeh E, Farzadi L, Khodarahmin M, Mehdinejadiani S, Sobhani A. The Wnt/beta-catenin signaling in endometriosis, the expression of total and active forms of beta-catenin, total and inactive forms of glycogen synthase kinase-3beta, WNT7a and DICKKOPF-1. Eur J Obstet Gynecol Reprod Biol. 2018;220:1–5.
Article
CAS
PubMed
Google Scholar
Dunlap KA, Filant J, Hayashi K, Rucker EB 3rd, Song G, Deng JM, Behringer RR, DeMayo FJ, Lydon J, Jeong JW, et al. Postnatal deletion of Wnt7a inhibits uterine gland morphogenesis and compromises adult fertility in mice. Biol Reprod. 2011;85(2):386–96.
Article
CAS
PubMed
PubMed Central
Google Scholar
Piotrowska-Tomala KK, Siemieniuch MJ, Szostek AZ, Korzekwa AJ, Woclawek-Potocka I, Galvao AM, Okuda K, Skarzynski DJ. Lipopolysaccharides, cytokines, and nitric oxide affect secretion of prostaglandins and leukotrienes by bovine mammary gland epithelial cells. Domest Anim Endocrinol. 2012;43(4):278–88.
Article
CAS
PubMed
Google Scholar
Mishra B, Koshi K, Kizaki K, Ushizawa K, Takahashi T, Hosoe M, Sato T, Ito A, Hashizume K. Expression of ADAMTS1 mRNA in bovine endometrium and placenta during gestation. Domest Anim Endocrinol. 2013;45(1):43–8.
Article
CAS
PubMed
Google Scholar
Keightley MC, Sales KJ, Jabbour HN. PGF2alpha-F-prostanoid receptor signalling via ADAMTS1 modulates epithelial cell invasion and endothelial cell function in endometrial cancer. BMC Cancer. 2010;10:488.
Article
PubMed
PubMed Central
CAS
Google Scholar
Esselens C, Malapeira J, Colome N, Casal C, Rodriguez-Manzaneque JC, Canals F, Arribas J. The cleavage of semaphorin 3C induced by ADAMTS1 promotes cell migration. J Biol Chem. 2010;285(4):2463–73.
Article
CAS
PubMed
Google Scholar
Rodriguez-Manzaneque JC, Carpizo D, Plaza-Calonge Mdel C, Torres-Collado AX, Thai SN, Simons M, Horowitz A, Iruela-Arispe ML. Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion. Int J Biochem Cell Biol. 2009;41(4):800–10.
Article
CAS
PubMed
Google Scholar
Bamberger AM, Minas V, Kalantaridou SN, Radde J, Sadeghian H, Loning T, Charalampopoulos I, Brummer J, Wagener C, Bamberger CM, et al. Corticotropin-releasing hormone modulates human trophoblast invasion through carcinoembryonic antigen-related cell adhesion molecule-1 regulation. Am J Pathol. 2006;168(1):141–50.
Article
CAS
PubMed
PubMed Central
Google Scholar
Krendl C, Shaposhnikov D, Rishko V, Ori C, Ziegenhain C, Sass S, Simon L, Muller NS, Straub T, Brooks KE, et al. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. Proc Natl Acad Sci U S A. 2017;114(45):E9579–88.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang X, Peng S, Cui K, Hou F, Ding J, Li A, Wang M, Geng L. MicroRNA-576-5p enhances the invasion ability of trophoblast cells in preeclampsia by targeting TFAP2A. Mol Genet Genomic Med. 2019;8:e1025.
PubMed
PubMed Central
Google Scholar
Corti F, Finetti F, Ziche M, Simons M. The syndecan-4/protein kinase Calpha pathway mediates prostaglandin E2-induced extracellular regulated kinase (ERK) activation in endothelial cells and angiogenesis in vivo. J Biol Chem. 2013;288(18):12712–21.
Article
CAS
PubMed
PubMed Central
Google Scholar
Xu H, Czerwinski P, Hortmann M, Sohn HY, Forstermann U, Li H. Protein kinase C alpha promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor. Cardiovasc Res. 2008;78(2):349–55.
Article
CAS
PubMed
Google Scholar
Zhang Q, Wang D, Singh NK, Kundumani-Sridharan V, Gadiparthi L, Rao Ch M, Rao GN. Activation of cytosolic phospholipase A2 downstream of the Src-phospholipase D1 (PLD1)-protein kinase C gamma (PKCgamma) signaling axis is required for hypoxia-induced pathological retinal angiogenesis. J Biol Chem. 2011;286(25):22489–98.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lu Y, Li Z, Xie B, Song Y, Ye X, Liu P. hsa-miR-20a-5p attenuates allergic inflammation in HMC-1 cells by targeting HDAC4. Mol Immunol. 2019;107:84–90.
Article
CAS
PubMed
Google Scholar
Moon J, Kaowinn S, Cho IR, Min DS, Myung H, Oh S, Kaewpiboon C, Kraemer OH, Chung YH. Hepatitis C virus core protein enhances hepatocellular carcinoma cells to be susceptible to oncolytic vesicular stomatitis virus through down-regulation of HDAC4. Biochem Biophys Res Commun. 2016;474(3):428–34.
Article
CAS
PubMed
Google Scholar
Yang D, Xiao C, Long F, Su Z, Jia W, Qin M, Huang M, Wu W, Suguro R, Liu X, et al. HDAC4 regulates vascular inflammation via activation of autophagy. Cardiovasc Res. 2018;114(7):1016–28.
Article
CAS
PubMed
Google Scholar
Zenke K, Muroi M, Tanamoto KI. AKT1 distinctively suppresses MyD88-depenedent and TRIF-dependent toll-like receptor signaling in a kinase activity-independent manner. Cell Signal. 2018;43:32–9.
Article
CAS
PubMed
Google Scholar
Singer JW, Fleischman A, Al-Fayoumi S, Mascarenhas JO, Yu Q, Agarwal A. Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy. Oncotarget. 2018;9(70):33416–39.
Article
PubMed
PubMed Central
Google Scholar
Socha BM, Lada P, Szczepanska AA, Lupicka M, Korzekwa AJ. The influence of experimentally induced endometritis on the PPAR expression profile in the bovine endometrium. Theriogenology. 2018;122:74–83.
Article
CAS
PubMed
Google Scholar
Chankeaw W, Guo YZ, Bage R, Svensson A, Andersson G, Humblot P. Elevated non-esterified fatty acids impair survival and promote lipid accumulation and pro-inflammatory cytokine production in bovine endometrial epithelial cells. Reprod Fertil Dev. 2018;30:1770–8.
Article
CAS
PubMed
Google Scholar
Babraham Bioinformatics Trim Galore. https://www.bioinformatics.babraham.ac.uk/projects/trim_galore/..
Guo W, Fiziev P, Yan W, Cokus S, Sun X, Zhang MQ, Chen PY, Pellegrini M. BS-Seeker2: a versatile aligning pipeline for bisulfite sequencing data. BMC Genomics. 2013;14:774.
Article
CAS
PubMed
PubMed Central
Google Scholar
Akalin A, Kormaksson M, Li S, Garrett-Bakelman FE, Figueroa ME, Melnick A, Mason CE. methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles. Genome Biol. 2012;13(10):R87.
Article
PubMed
PubMed Central
Google Scholar