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Table 2 The background information and their distribution of differentially acetylated sites at lysines in proteins

From: Protein acetylation in mitochondria plays critical functions in the pathogenesis of fatty liver disease

Protein accession number

Protein name

Number of potential modification sites

Number of differentially acetylated sites

Position

Modified sequencea

Average fold change of acetylated level by FL/Norm

Maximum P valueb

Q3SZ00

HADHA

23

14

516

MQLLEIITTEK(1)TSK

1.50 ± 0.49 (n = 14)

≤0.0469

P79134

ANXA6

17

13

306

SLYSMIK(1)NDTSGEYK

0.59 ± 0.11 (n = 13)

≤0.0473

F1ML89

CPS1

35

11

875

LTSIDK(1)WFLYK

1.31 ± 0.25 (n = 11)

≤0.0179

P12344

GOT2

16

11

90

K(1)AEAQIAAK(1)NLDK

1.31 ± 0.25 (n = 11)

≤0.0354

Q2KIE6

HMGCS2

13

11

350

LEDTYTNK(1)DVDK(1)AFLK

1.96 ± 0.82 (n = 11)

≤0.0496

Q29RZ0

ACAT1

14

10

197

IHMGNCAENTAK(1)K

1.86 ± 0.38 (n = 10)

≤0.0169

A0A140T871

GLUD1

18

9

460

LTFK(1)YER

1.42 ± 0.30 (n = 9)

≤0.0495

F1N7K8

ALDH6A1

10

9

333

K(1)WLPELVER

1.34 ± 0.30 (n = 9)

≤0.0246

F1MQV8

ACSS3

13

8

124

HIENGK(1)GDK

1.68 ± 0.24 (n = 8)

≤0.0083

Q3ZCH0

HSPA9

10

8

612

LK(1)EEISK

1.41 ± 0.43 (n = 8)

≤0.0302

Q3T0R7

ACAA2

11

7

240

QTMQVDEHPRPQTTMEQLNK(1)LPPVFK(1)K

1.47 ± 0.41 (n = 7)

≤0.0416

F1MV74

SCP2

9

7

189

NHK(1)HSVNNPYSQFQK

0.37 ± 0.07 (n = 7)

≤0.0017

Q5E9F8

H3F3A

8

7

28

K(1)SAPSTGGVK(0.857)K(0.143)PHR

0.58 ± 0.06 (n = 7)

≤0.0426

Q32LG3

MDH2

14

6

328

ASIK(1)K(1)GEEFVK

1.53 ± 0.21 (n = 6)

≤0.0017

F1N206

DLD

12

6

159

ITGK(1)NQVTATK

1.26 ± 0.36 (n = 6)

≤0.0191

P05307

P4HB

11

6

387

NFEEVAFDEK(1)K

0.56 ± 0.06 (n = 6)

≤0.0151

P20000

ALDH2

11

6

371

TEQGPQVDETQFK(1)K

1.26 ± 0.29 (n = 6))

≤0.0176

O46629

HADHB

10

6

189

MMLDLNK(1)AK(1)TLAQR

1.43 ± 0.34 (n = 6)

≤0.0350

Q0VCM4

PYGL

9

6

465

IHSDIVK(1)TQVFK

0.61 ± 0.08 (n = 6)

≤0.0433

F1MZP8

_

7

6

348

LVTDFMAK(1)K

0.70 ± 0.06 (n = 6)

≤0.0358

P52898

_

7

6

161

DAGLTK(1)SIGVSNFNHK

0.63 ± 0.09 (n = 6)

≤0.0217

  1. a Shown is the distribution range of P-values of all the aceltylated sites in this protein by picking up the ultimate value
  2. b Identified peptide sequence containing acetylated modification sites marked with localization and probabilities
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BMC Genomics

ISSN: 1471-2164

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