Weismann. Über die Dauer des Lebens. Am J Psychol. 1890;3(1):105.
Article
Google Scholar
Medawar PB. An Unsolved Problem of Biology. Evolution in Health and Disease. London: H.K. Lewis; 1951.
Google Scholar
Williams GC. Pleiotropy, natural selection, and the evolution of senescence. Evolution. 1957;11:398–411.
Article
Google Scholar
Flatt T, Partridge L. Horizons in the evolution of aging. BMC Biol. 2018;16:1–13.
Article
CAS
Google Scholar
Gaillard JM, Lemaître JF. An integrative view of senescence in nature. Funct Ecol. 2020;34:4–16.
Article
Google Scholar
Finkel T, Holbrook NJ. Oxidants, oxidative stress and biology of ageing. Insight Rev Artic. 2000;408:239–47.
CAS
Google Scholar
Metcalfe NB, Alonso-Alvarez C. Oxidative stress as a life-history constraint: the role of reactive oxygen species in shaping phenotypes from conception to death. Funct Ecol. 2010;24:984–96.
Article
Google Scholar
Heidinger BJ, Blount JD, Boner W, Griffiths K, Metcalfe NB, Monaghan P. Telomere length in early life predicts lifespan. Proc Natl Acad Sci U S A. 2012;109:1743–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gems D, Partridge L. Genetics of longevity in model organisms: debates and paradigm shifts. Annu Rev Physiol. 2013;75:621–44.
Article
CAS
PubMed
Google Scholar
Rattan SIS. Theories of biological aging: genes, proteins, and free radicals. Free Radic Res. 2006;40:1230–8.
Article
CAS
PubMed
Google Scholar
Partridge L, Gems D. Mechanisms of ageing: public or private? Nat Rev Genet. 2002;3:165–75.
Article
CAS
PubMed
Google Scholar
Narasimhan SD, Yen K, Tissenbaum HA. Converging pathways in lifespan regulation. Curr Biol. 2009;19(15):R657–66.
Article
CAS
PubMed
PubMed Central
Google Scholar
Flatt T, Amdam GV, Kirkwood TBL, Omholt SW. Life-history evolution and the polyphenic regulation of somatic maintenance and survival. Q Rev Biol. 2013;88:185–218.
Article
PubMed
Google Scholar
Fontana L, Partridge L. Promoting health and longevity through diet: from model organisms to humans. Cell. 2015;161:106–18.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ottaviani E, Ventura N, Mandrioli M, Candela M, Franchini A, Franceschi C. Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms. Biogerontology. 2011;12:599–609.
Article
CAS
PubMed
Google Scholar
Obata F, Fons CO, Gould AP. Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila. Nat Commun. 2018;9:975.
Article
PubMed
PubMed Central
CAS
Google Scholar
Gould AL, Zhang V, Lamberti L, Jones EW, Obadia B, Korasidis N, et al. Microbiome interactions shape host fitness. Proc Natl Acad Sci U S A. 2018;115:E11951–60.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kwong WK, Moran NA. Gut microbial communities of social bees. Nat Rev Microbiol. 2016;14:374–84.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fabian DK, Garschall K, Klepsatel P, Santos-Matos G, Sucena É, Kapun M, et al. Evolution of longevity improves immunity in Drosophila. Evol Lett. 2018;2:567–79.
Article
PubMed
PubMed Central
Google Scholar
Moret Y, Schmid-Hempel P. Survival for immunity: the price of immune system activation for bumblebee workers. Science. 2000;290:1166–8.
Article
CAS
PubMed
Google Scholar
Korb J. Why do social insect queens live so long? Approaches to unravel the sociality-aging puzzle. Curr Opin Insect Sci. 2016;16:104–7.
Article
PubMed
Google Scholar
Heinze J, Schrempf A. Aging and reproduction in social insects - a mini-review. Gerontology. 2008;54:160–7.
Article
PubMed
Google Scholar
Kohlmeier P, Negroni MA, Kever M, Emmling S, Stypa H, Feldmeyer B, et al. Intrinsic worker mortality depends on behavioral caste and the queens’ presence in a social insect. Sci Nat. 2017;104:34.
Article
CAS
Google Scholar
Keller L, Jemielity S. Social insects as a model to study the molecular basis of ageing. Exp Gerontol. 2006;41:553–6.
Article
CAS
PubMed
Google Scholar
Konrad M, Pamminger T, Foitzik S. Two pathways ensuring social harmony. Naturwissenschaften. 2012;99:627–36.
Article
CAS
PubMed
Google Scholar
Rodrigues MA, Flatt T. Endocrine uncoupling of the trade-off between reproduction and somatic maintenance in eusocial insects. Curr Opin Insect Sci. 2016;16:1–8.
Article
PubMed
Google Scholar
Sun J, Tower J. FLP Recombinase-mediated induction of cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies. Mol Cell Biol. 1999;19(1):216–28.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tasaki E, Kobayashi K, Matsuura K, Iuchi Y. An efficient antioxidant system in a long-lived termite queen. PLoS One. 2017;12:e0167412.
Article
PubMed
PubMed Central
CAS
Google Scholar
O’Toole PW, Jeffery IB. Gut microbiota and aging. Science. 2015;350:1214–5.
Article
PubMed
CAS
Google Scholar
Zheng H, Powell JE, Steele MI, Dietrich C, Moran NA. Honeybee gut microbiota promotes host weight gain via bacterial metabolism and hormonal signaling. Proc Natl Acad Sci U S A. 2017;114:4775–80.
Article
CAS
PubMed
PubMed Central
Google Scholar
Clark RI, Salazar A, Yamada R, Fitz-Gibbon S, Morselli M, Alcaraz J, et al. Distinct shifts in microbiota composition during Drosophila aging impair intestinal function and drive mortality. Cell Rep. 2015;12:1656–67.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ikeda T, Yasui C, Hoshino K, Arikawa K, Nishikawa Y. Influence of lactic acid bacteria on longevity of Caenorhabditis elegans and host defense against Salmonella enterica serovar Enteritidis. Appl Environ Microbiol. 2007;73:6404–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Komura T, Ikeda T, Yasui C, Saeki S, Nishikawa Y. Mechanism underlying prolongevity induced by bifidobacteria in Caenorhabditis elegans. Biogerontology. 2013;14:73–87.
Article
CAS
PubMed
Google Scholar
Flatt T, Garschall K. The interplay between immunity and aging in Drosophila. F1000Res. 2018;7:160.
Article
PubMed
PubMed Central
CAS
Google Scholar
Negroni MA, Foitzik S, Feldmeyer B. Long-lived Temnothorax ant queens switch from investment in immunity to antioxidant production with age. Sci Rep. 2019;9:7270.
Article
PubMed
PubMed Central
CAS
Google Scholar
Hoffmann JA. The immune response of Drosophila. Nature. 2003;426:33–8.
Article
CAS
PubMed
Google Scholar
Palakurty SX, Stinchcombe JR, Afkhami ME. Cooperation and coexpression: how coexpression networks shift in response to multiple mutualists. Mol Ecol. 2018;27:1860–73.
Article
PubMed
Google Scholar
Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014;510:397–401.
Article
CAS
PubMed
PubMed Central
Google Scholar
Engel P, Moran NA. The gut microbiota of insects - diversity in structure and function. FEMS Microbiol Rev. 2013;37:699–735.
Article
CAS
PubMed
Google Scholar
Van Borm S, Buschinger A, Boomsma JJ, Billen J. Tetraponera ants have gut symbionts related to nitrogen-fixing root-nodule bacteria. Proc R Soc B Biol Sci. 2008;49:2023–7.
Google Scholar
Segers FH, Kešnerová L, Kosoy M, Engel P. Genomic changes associated with the evolutionary transition of an insect gut symbiont into a blood-borne pathogen. ISME J. 2017;11:1232–44.
Article
CAS
PubMed
PubMed Central
Google Scholar
Liberti J, Sapountzis P, Hansen LH, Sørensen SJ, Adams RMM, Boomsma JJ. Bacterial symbiont sharing in Megalomyrmex social parasites and their fungus-growing ant hosts. Mol Ecol. 2015;24:3151–69.
Article
PubMed
PubMed Central
Google Scholar
Mathew GM, Ju YM, Lai CY, Mathew DC, Huang CC. Microbial community analysis in the termite gut and fungus comb of Odontotermes formosanus: the implication of Bacillus as mutualists. FEMS Microbiol Ecol. 2012;79:504–17.
Article
CAS
PubMed
Google Scholar
Aksoy E, Telleria EL, Echodu R, Wu Y, Okedi LM, Weiss BL, et al. Analysis of multiple tsetse fly populations in Uganda reveals limited diversity and species-specific gut microbiota. Appl Environ Microbiol. 2014;80:4301–12.
Article
PubMed
PubMed Central
CAS
Google Scholar
Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D. Alpha-ketoglutarate: physiological functions and applications. Biomol Ther. 2016;24:1–8.
Article
CAS
Google Scholar
Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, et al. 2-hydroxyglutarate inhibits ATP synthase and mTOR signaling. Cell Metab. 2015;22:508–15.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bayliak MM, Lylyk MP, Shmihel HV, Sorochynska OM, Manyukh OV, Pierzynowski SG, et al. Dietary alpha-ketoglutarate increases cold tolerance in Drosophila melanogaster and enhances protein pool and antioxidant defense in sex-specific manner. J Therm Biol. 2016;60:1–11. https://doi.org/10.1016/j.jtherbio.2016.06.001.
Article
CAS
PubMed
Google Scholar
Teleman AA, Chen YW, Cohen SM. 4E-BP functions as a metabolic brake used under stress conditions but not during normal growth. Genes Dev. 2005;19:1844–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lu HL, Vinson SB, Pietrantonio PV. Oocyte membrane localization of vitellogenin receptor coincides with queen flying age, and receptor silencing by RNAi disrupts egg formation in fire ant virgin queens. FEBS J. 2009;276:3110–23.
Article
CAS
PubMed
Google Scholar
Feldmeyer B, Elsner D, Foitzik S. Gene expression patterns associated with caste and reproductive status in ants: worker-specific genes are more derived than queen-specific ones. Mol Ecol. 2014;23:151–61.
Article
CAS
PubMed
Google Scholar
Lee BC, Kaya A, Ma S, Kim G, Gerashchenko MV, Yim SH, et al. Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status. Nat Commun. 2014;5:3592.
Article
PubMed
CAS
Google Scholar
Obata F, Miura M. Enhancing S-adenosyl-methionine catabolism extends Drosophila lifespan. Nat Commun. 2015;6:8332.
Article
CAS
PubMed
Google Scholar
Lucas ER, Keller L. The co-evolution of longevity and social life. Funct Ecol. 2020;34:76–87.
Article
Google Scholar
Marra NJ, Stanhope MJ, Jue NK, Wang M, Sun Q, Bitar PP, et al. White shark genome reveals ancient elasmobranch adaptations associated with wound healing and the maintenance of genome stability. Proc Natl Acad Sci U S A. 2019;116:4446–55.
Article
CAS
PubMed
PubMed Central
Google Scholar
Steiner H. Peptidoglycan recognition proteins: on and off switches for innate immunity. Immunol Rev. 2004;198:83–96.
Article
CAS
PubMed
Google Scholar
Song JW, Lim SJ, Lee KJ. Effects of dietary supplementation of inosine monophosphate on growth performance, innate immunity and disease resistance of olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2012;33:1050–4.
Article
PubMed
CAS
Google Scholar
Navrotskaya V, Oxenkrug G. Effect of kynurenic acid on development and aging in wild type and vermilion mutants of Drosophila melanogaster. Pharmacol Drug Dev Ther. 2016;1:10.
Article
PubMed Central
Google Scholar
Buchmann K. Evolution of innate immunity: clues from invertebrates via fish to mammals. Front Immunol. 2014;5:459.
Article
PubMed
PubMed Central
CAS
Google Scholar
Kutsukake M, Moriyama M, Shigenobu S, Meng XY, Nikoh N, Noda C, et al. Exaggeration and cooption of innate immunity for social defense. Proc Natl Acad Sci U S A. 2019;116:8950–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wong JMY, Collins K. Telomere maintenance and disease. Lancet. 2003;362:983–8.
Article
CAS
PubMed
Google Scholar
Dantoft W, Davis MM, Lindvall JM, Tang X, Uvell H, Junell A, et al. The Oct1 homolog nubbin is a repressor of NF-κB-dependent immune gene expression that increases the tolerance to gut microbiota. BMC Biol. 2013;11:99.
Article
PubMed
PubMed Central
CAS
Google Scholar
Dantoft W, Lundin D, Esfahani SS, Engström Y. The POU/Oct transcription factor Pdm1/nub is necessary for a beneficial gut microbiota and Normal lifespan of Drosophila. J Innate Immun. 2016;8:412–26.
Article
CAS
PubMed
PubMed Central
Google Scholar
Garrett WS, Gordon JI, Glimcher LH. Homeostasis and inflammation in the intestine. Cell. 2010;140:859–70.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mistry R, Kounatidis I, Ligoxygakis P. Interaction between familial transmission and a constitutively active immune system shapes gut microbiota in Drosophila melanogaster. Genetics. 2017;206:889–904.
Article
CAS
PubMed
PubMed Central
Google Scholar
Vieira CS, Waniek PJ, Castro DP, Mattos DP, Moreira OC, Azambuja P. Impact of Trypanosoma cruzi on antimicrobial peptide gene expression and activity in the fat body and midgut of Rhodnius prolixus. Parasit Vectors. 2016;9:119.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hu Y, Sanders JG, Łukasik P, D’Amelio CL, Millar JS, Vann DR, et al. Herbivorous turtle ants obtain essential nutrients from a conserved nitrogen-recycling gut microbiome. Nat Commun. 2018;9:964.
Article
PubMed
PubMed Central
CAS
Google Scholar
Salem H, Kreutzer E, Sudakaran S, Kaltenpoth M. Actinobacteria as essential symbionts in firebugs and cotton stainers (Hemiptera, Pyrrhocoridae). Environ Microbiol. 2013;15:1956–68.
Article
PubMed
Google Scholar
Caudal HG, Ryu J, Kim S, Lee H, Bai JY, Nam Y, et al. Innate immune homeostasis by the Homeobox gene Caudal and commensal-gut mutualism in Drosophila. Science. 2008;319:777–82.
Article
CAS
Google Scholar
Rosengaus RB, Zecher CN, Schultheis KF, Brucker RM, Bordenstein SR. Disruption of the termite gut microbiota and its prolonged consequences for fitness. Appl Environ Microbiol. 2011;77:4303–12.
Article
CAS
PubMed
PubMed Central
Google Scholar
Segers FHID, Kaltenpoth M, Foitzik S. Abdominal microbial communities in ants depend on colony membership rather than caste and are linked to colony productivity. Ecol Evol. 2019;9:13450–67.
Article
PubMed
PubMed Central
Google Scholar
Grüter C, Acosta LE, Farina WM. Propagation of olfactory information within the honeybee hive. Behav Ecol Sociobiol. 2006;60:707–15.
Article
Google Scholar
Powell JE, Martinson VG, Urban-Mead K, Moran NA. Routes of acquisition of the gut microbiota of the honey bee Apis mellifera. Appl Environ Microbiol. 2014;80:7378–87.
Article
PubMed
PubMed Central
CAS
Google Scholar
Zhang LJ, Gallo RL. Antimicrobial peptides. Curr Biol. 2016;26:R14–9.
Article
CAS
PubMed
Google Scholar
Bulet P, Hetru C, Dimarcq JL, Hoffmann D. Antibacterial peptides in insects; structure and function. Dev Comp Immunol. 1999;23:329–44.
Article
CAS
PubMed
Google Scholar
Casteels P, Ampell C, Jacobs F, Tempst P. Functional and chemical characterization of Hymenoptaecin, an antibacterial polypeptide that is infection-inducible in the honeybee. J Biol Chem. 1993;268:7044.
CAS
PubMed
Google Scholar
Brunner E, Kroiss J, Trindl A, Heinze J. Queen pheromones in Temnothorax ants: control or honest signal? BMC Evol Biol. 2011;11:55.
Article
PubMed
PubMed Central
Google Scholar
Kohlmeier P, Feldmeyer B, Foitzik S. Vitellogenin-like A–associated shifts in social cue responsiveness regulate behavioral task specialization in an ant. PLoS Biol. 2018;16:e2005747.
Article
PubMed
PubMed Central
CAS
Google Scholar
Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30:2114–20.
Article
CAS
PubMed
PubMed Central
Google Scholar
Haas BJ, Papanicolaou A, Yassour M, Grabherr M, Blood PD, Bowden J, et al. De novo transcript sequence reconstruction from RNA-seq using the trinity platform for reference generation and analysis. Nat Protoc. 2013;8:1494–512.
Article
CAS
PubMed
Google Scholar
Jones P, Binns D, Chang HY, Fraser M, Li W, McAnulla C, et al. InterProScan 5: genome-scale protein function classification. Bioinformatics. 2014;30:1236–40.
Article
CAS
PubMed
PubMed Central
Google Scholar
Li B, Dewey CN. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics. 2011;12:323.
Article
CAS
PubMed
PubMed Central
Google Scholar
Anders S. Analysing RNA-Seq data with the DESeq package. 2011. http://www-huber.embl.de/users/.
Google Scholar
Alexa A, Maintainer JR. Package “topGO” type package title enrichment analysis for gene ontology. 2020. https://git.bioconductor.org/packages/topGO.
Google Scholar
Edgar RC. UPARSE: highly accurate OTU sequences from microbial amplicon reads. Nat Methods. 2013;10:996–8.
Article
CAS
PubMed
Google Scholar
Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, et al. QIIME allows analysis of high-throughput community sequencing data. Nat Methods. 2010;7:335–6.
Article
CAS
PubMed
PubMed Central
Google Scholar
Suzuki R, Shimodaira H. Pvclust: an R package for assessing the uncertainty in hierarchical clustering. Bioinformatics. 2006;22:1540–2.
Article
CAS
PubMed
Google Scholar
Yu G, Smith DK, Zhu H, Guan Y, Lam TTY. Ggtree: an R package for visualization and annotation of phylogenetic trees with their covariates and other associated data. Methods Ecol Evol. 2017;8:28–36.
Article
Google Scholar
Paulson N, Stine OC, Bravo HC, Pop M. Differential abundance analysis for microbial marker-gene surveys. Nat Methods. 2013;10:1200–2.
Article
CAS
PubMed
PubMed Central
Google Scholar
Oksanen J, Kindt R, Legendre P, O’Hara B, Simpson GL, Solymos P, Wagner H. R package community ecology package Vegan; 2009.
Google Scholar