Table 3 Top five canonical pathways assembled from targets of differentially expressed sperm-borne miRNAs correlated with two-cell embryo competence
From: Sperm miRNAs— potential mediators of bull age and early embryo development
10 VS 16 months | 12 VS 16 months | ||||
|---|---|---|---|---|---|
Canonical Pathways | -log(p-value) | z-score | Canonical Pathways | -log(p-value) | z-score |
Mouse Embryonic Stem Cell Pluripotency | 4.81 | 2.111 | PI3K Signaling in B Lymphocytes | 3.62 | 3 |
Superpathway of Inositol Phosphate Compounds | 3.63 | 3.207 | iCOS-iCOSL Signaling in T Helper Cells | 3.22 | 2.646 |
Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency | 3.61 | 2.646 | Inhibition of Angiogenesis by TSP1 | 2.79 | 2 |
Thrombin Signaling | 3.41 | 2.714 | Non-Small Cell Lung Cancer Signaling | 2.68 | 2.236 |
3-phosphoinositide Biosynthesis | 3.21 | 2.887 | Telomerase Signaling | 2.61 | 2.449 |