Hayes BJ, Bowman PJ, Chamberlain AJ, Goddard ME. Invited review: genomic selection in dairy cattle: Progress and challenges. J Dairy Sci. 2009;92(2):433–43.
Wolf F, Almquist J, Hale E. Prepuberal behavior and puberal characteristics of beef bulls on high nutrient allowance. J Anim Sci. 1965;24(3):761–5.
Takeda K, Kobayashi E, Akagi S, Nishino K, Kaneda M, Watanabe S. Differentially methylated CpG sites in bull spermatozoa revealed by human DNA methylation arrays and bisulfite analysis. J Reprod Dev. 2017;63(3):279–87.
Okada Y, Yamaguchi K. Epigenetic modifications and reprogramming in paternal pronucleus: sperm, preimplantation embryo, and beyond. Cell Mol Life Sci. 2017;74(11):1957–67.
Siklenka K, Erkek S, Godmann M, Lambrot R, McGraw S, Lafleur C, et al. Disruption of histone methylation in developing sperm impairs offspring health transgenerationally. Science. 2015;350(6261):aab2006.
Skinner MK, Ben Maamar M, Sadler-Riggleman I, Beck D, Nilsson E, McBirney M, et al. Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease. Epigenetics Chromatin. 2018;11(1):8.
Govindaraju A, Uzun A, Robertson L, Atli MO, Kaya A, Topper E, et al. Dynamics of microRNAs in bull spermatozoa. Reprod Biol Endocrinol. 2012;10(1):82.
Fagerlind M, Stålhammar H, Olsson B, Klinga-Levan K. Expression of miRNAs in bull spermatozoa correlates with fertility rates. Reprod Domest Anim. 2015;50(4):587–94.
Kutchy NA, Menezes ESB, Chiappetta A, Tan W, Wills RW, Kaya A, et al. Acetylation and methylation of sperm histone 3 lysine 27 (H3K27ac and H3K27me3) are associated with bull fertility. Andrologia. 2018;50(3):e12915.
Ugur MR, Kutchy NA, de Menezes EB, Ul-Husna A, Haynes BP, Uzun A, et al. Retained acetylated histone four in bull sperm associated with fertility. Front Vet Sci. 2019;6:223.
Lambert S, Blondin P, Vigneault C, Labrecque R, Dufort I, Sirard M-A. Spermatozoa DNA methylation patterns differ due to peripubertal age in bulls. Theriogenology. 2018;106(Supplement C):21–9.
Takeda K, Kobayashi E, Nishino K, Imai A, Adachi H, Hoshino Y, et al. Age-related changes in DNA methylation levels at CpG sites in bull spermatozoa and in vitro fertilization-derived blastocyst-stage embryos revealed by combined bisulfite restriction analysis. J Reprod Dev. 2019;65(4):305–12.
Fullston T, Ohlsson Teague EMC, Palmer NO, DeBlasio MJ, Mitchell M, Corbett M, et al. Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content. FASEB J. 2013;27(10):4226–43.
Gapp K, Jawaid A, Sarkies P, Bohacek J, Pelczar P, Prados J, et al. Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice. Nat Neurosci. 2014;17:667.
Sharma U, Conine CC, Shea JM, Boskovic A, Derr AG, Bing XY, et al. Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. Science. 2016;351(6271):391–6.
Chen Q, Yan M, Cao Z, Li X, Zhang Y, Shi J, et al. Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder. Science. 2016;351(6271):397–400.
Yuan S, Schuster A, Tang C, Yu T, Ortogero N, Bao J, et al. Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development. Development. 2016;143(4):635–47.
Liu WM, Pang RTK, Chiu PCN, Wong BPC, Lao KQ, Lee KF, et al. Sperm-borne microRNA-34c is required for the first cleavage division in mouse. Proc Natl Acad Sci U S A. 2012;109(2):490–4.
Du Y, Wang X, Wang B, Chen W, He R, Zhang L, et al. Deep sequencing analysis of microRNAs in bovine sperm. Mol Reprod Dev. 2014;81(11):1042–52.
Gilchrist GC, Tscherner A, Nalpathamkalam T, Merico D, LaMarre J. MicroRNA expression during bovine oocyte maturation and fertilization. Int J Mol Sci. 2016;17(3):396.
Andrade G, Meirelles F, Perecin F, da Silveira J. Cellular and extracellular vesicular origins of miRNAs within the bovine ovarian follicle. Reprod Domest Anim. 2017;52(6):1036–45.
Agarwal V, Bell GW, Nam J-W, Bartel DP. Predicting effective microRNA target sites in mammalian mRNAs. Elife. 2015;4:e05005.
Orozco-Lucero E, Dufort I, Robert C, Sirard MA. Rapidly cleaving bovine two-cell embryos have better developmental potential and a distinctive mRNA pattern. Mol Reprod Dev. 2014;81(1):31–41.
Dode MAN, Dufort I, Massicotte L, Sirard MA. Quantitative expression of candidate genes for developmental competence in bovine two-cell embryos. Mol Reprod Dev. 2006;73(3):288–97.
Lonergan P, Khatir H, Piumi F, Rieger D, Humblot P, Boland MP. Effect of time interval from insemination to first cleavage on the developmental characteristics, sex ratio and pregnancy rate after transfer of bovine embryos. Reproduction. 1999;117(1):159–67.
Memili E, First NL. Zygotic and embryonic gene expression in cow: a review of timing and mechanisms of early gene expression as compared with other species. Zygote. 2000;8(1):87–96.
Kues WA, Sudheer S, Herrmann D, Carnwath JW, Havlicek V, Besenfelder U, et al. Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo. Proc Natl Acad Sci U S A. 2008;105(50):19768–73.
Tscherner A, Gilchrist G, Smith N, Blondin P, Gillis D, LaMarre J. MicroRNA-34 family expression in bovine gametes and preimplantation embryos. Reprod Biol Endocrinol. 2014;12(1):85.
Wu C, Blondin P, Vigneault C, Labrecque R, Sirard M-A. The age of the bull influences the transcriptome and epigenome of blastocysts produced by IVF. Theriogenology. 2020;144:122–31.
Yuan S, Tang C, Zhang Y, Wu J, Bao J, Zheng H, et al. Mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice. Biol Open. 2015;4(2):212–23.
Rando OJ. Daddy issues: paternal effects on phenotype. Cell. 2012;151(4):702–8.
Wang L, Zhang J, Duan J, Gao X, Zhu W, Lu X, et al. Programming and inheritance of parental DNA methylomes in mammals. Cell. 2014;157(4):979–91.
Radford EJ, Ito M, Shi H, Corish JA, Yamazawa K, Isganaitis E, et al. In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism. Science. 2014;345(6198):1255903.
Shea Jeremy M, Serra Ryan W, Carone Benjamin R, Shulha Hennady P, Kucukural A, Ziller Michael J, et al. Genetic and epigenetic variation, but not diet. Shape Sperm Methylome Dev Cell. 2015;35(6):750–8.
Rodgers AB, Morgan CP, Leu NA, Bale TL. Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress. Proc Natl Acad Sci U S A. 2015;112(44):13699–704.
Sharma R, Agarwal A, Rohra VK, Assidi M, Abu-Elmagd M, Turki RF. Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring. Reprod Biol Endocrinol. 2015;13(1):35.
Amanai M, Brahmajosyula M, Perry ACF. A restricted role for sperm-borne MicroRNAs in mammalian Fertilization1. Biol Reprod. 2006;75(6):877–84.
Grandjean V, Fourré S, De Abreu DAF, Derieppe M-A, Remy J-J, Rassoulzadegan M. RNA-mediated paternal heredity of diet-induced obesity and metabolic disorders. Sci Rep. 2015;5(1):18193.
Short A, Yeshurun S, Powell R, Perreau V, Fox A, Kim J, et al. Exercise alters mouse sperm small noncoding RNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety. Transl Psychiatry. 2017;7(5):e1114.
Krämer A, Green J, Pollard J Jr, Tugendreich S. Causal analysis approaches in ingenuity pathway analysis. Bioinformatics. 2013;30(4):523–30.
Breese CR, Ingram RL, Sonntag WE. Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1), IGF-1 gene expression, and IGF-1 binding proteins. J Gerontol. 1991;46(5):B180–7.
Greer KA, Hughes LM, Masternak MM. Connecting serum IGF-1, body size, and age in the domestic dog. AGE. 2011;33(3):475–83.
Bourgon SL, Diel de Amorim M, Miller SP, Montanholi YR. Associations of blood parameters with age, feed efficiency and sampling routine in young beef bulls. Livest Sci. 2017;195:27–37.
Matsui M, Takahashi Y, Hishinuma M, Kanagawa H. Insulin and insulin-like growth factor-I (IGF-I) stimulate the development of bovine embryos fertilized in vitro. J Vet Med Sci. 1995;57(6):1109–11.
Sirisathien S, Hernandez-Fonseca HJ, Brackett BG. Influences of epidermal growth factor and insulin-like growth factor-I on bovine blastocyst development in vitro. Anim Reprod Sci. 2003;77(1–2):21–32.
Tríbulo P, Jumatayeva G, Lehloenya K, Moss JI, Negrón-Pérez VM, Hansen PJ. Effects of sex on response of the bovine preimplantation embryo to insulin-like growth factor 1, activin A, and WNT7A. BMC Dev Biol. 2018;18(1):16.
Chi MM, Schlein AL, Moley KH. High insulin-like growth factor 1 (IGF-1) and insulin concentrations trigger apoptosis in the mouse blastocyst via down-regulation of the IGF-1 receptor. Endocrinology. 2000;141(12):4784–92.
Moley KH, Bibee K, Wyman A, Eng GS. IGF-1 induced blastocyst apoptosis is p53 dependent. Fertil Steril. 2005;84:S388.
Velazquez MA, Hermann D, Kues WA, Niemann H. Increased apoptosis in bovine blastocysts exposed to high levels of IGF1 is not associated with downregulation of the IGF1 receptor. Reproduction. 2011;141(1):91–103.
Liu C, Peng G, Jing N. TGF-β signaling pathway in early mouse development and embryonic stem cells. Acta Biochim Biophys Sin. 2017;50(1):68–73.
Roelen BAJ, Goumans M-J, Zwijsen A, Mummery CL. Identification of two distinct functions for TGF-β in early mouse development. Differentiation. 1998;64(1):19–31.
Moore GD, Ayabe T, Visconti PE, Schultz RM, Kopf GS. Roles of heterotrimeric and monomeric G proteins in sperm-induced activation of mouse eggs. Development. 1994;120(11):3313–23.
Cui X-S, Li X-Y, Kim N-H. Cdc42 is implicated in polarity during meiotic resumption and blastocyst formation in the mouse. Mol Reprod Dev. 2007;74(6):785–94.
Clayton L, Hall A, Johnson MH. A role for rho-like GTPases in the polarisation of mouse eight-cell Blastomeres. Dev Biol. 1999;205(2):322–31.
Mayer JP, Zhang F, DiMarchi RD. Insulin structure and function. Biopolymers. 2007;88(5):687–713.
Siddle K. Signalling by insulin and IGF receptors: supporting acts and new players. J Mol Endocrinol. 2011;47(1):R1–10.
Guo S. Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models into disease mechanisms. J Endocrinol. 2014;220(2):T1–t23.
Schultz GA, Hogan A, Watson AJ, Smith RM, Heyner S. Insulin, insulin-like growth factors and glucose transporters: temporal patterns of gene expression in early murine and bovine embryos. Reprod Fertil Dev. 1992;4(4):361–71.
Keogh K, Kenny DA, Kelly AK, Waters SM. Insulin secretion and signaling in response to dietary restriction and subsequent re-alimentation in cattle. Physiol Genomics. 2015;47(8):344–54.
Thompson RP, Nilsson E, Skinner MK. Environmental epigenetics and epigenetic inheritance in domestic farm animals. Anim Reprod Sci. 2020;106316.
Ciapa B, Chiri S. Egg activation: upstream of the fertilization calcium signal. Biol Cell. 2000;92(3–4):215–33.
Malcuit C, Knott JG, He C, Wainwright T, Parys JB, Robl JM, et al. Fertilization and inositol 1,4,5-Trisphosphate (IP3)-induced calcium release in Type-1 inositol 1,4,5-Trisphosphate receptor Down-regulated bovine Eggs1. Biol Reprod. 2005;73(1):2–13.
Riley JK, Carayannopoulos MO, Wyman AH, Chi M, Ratajczak CK, Moley KH. The PI3K/Akt pathway is present and functional in the preimplantation mouse embryo. Dev Biol. 2005;284(2):377–86..
Zheng W, Gorre N, Shen Y, Noda T, Ogawa W, Lundin E, et al. Maternal phosphatidylinositol 3-kinase signalling is crucial for embryonic genome activation and preimplantation embryogenesis. EMBO Rep. 2010;11(11):890–5.
Kurosaka S, Eckardt S, McLaughlin KJ. Pluripotent lineage definition in bovine embryos by Oct4 transcript Localization1. Biol Reprod. 2004;71(5):1578–82.
Khan DR, Dubé D, Gall L, Peynot N, Ruffini S, Laffont L, et al. Expression of Pluripotency master regulators during two key developmental transitions: EGA and early lineage specification in the bovine embryo. PLoS One. 2012;7(3):1–12.
Vigneault C, Gravel C, Vallée M, McGraw S, Sirard M-A. Unveiling the bovine embryo transcriptome during the maternal-to-embryonic transition. Reproduction. 2009;137(2):245.
Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30(15):2114–20.
Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol. 2010;11(10):R106.