Table 4 Upstream regulators of the blastocyst transcriptome that are targets of sperm borne miRNAs
From: Sperm miRNAs— potential mediators of bull age and early embryo development
Upstream regulators in 10 vs 16 months | Downstream targets | Upstream regulators in 12 vs 16 months | Downstream targets |
|---|---|---|---|
RICTOR | ATP5MF, ATP6V0A4, ATP6V1D, etc. 24 genes | RICTOR | ATP5PD, ATP6V0D2, COX7A2L, etc. 18 genes |
KDM5A | ACTC1, ATP6V1D, ATP6V1F, etc. 15 genes | STK11 | ATIC, AVIL, CCNA2, etc. 14 genes |
CREB1 | CHRNA1, CNN1, CSRP2, etc. 21 genes | KDM5A | COQ7, MCM3, MYL4, etc. 7 genes |
AREG | CCNA2, CENPF, PRC1, etc. 5 genes |