Fig. 5
Expression of genes associated with the high osmolarity glycerol pathway in the fludioxonil-resistant strains. a A reproduction of the high osmolarity glycerol (HOG) pathway of Saccharomyces cerevisiae. Green circles had homologues in the Sclerotinia sclerotiorum proteome. Those outlined in red are known to be involved in transcriptional regulation of other genes. b Expression of the HOG pathway homologues in S. sclerotiorum. Again, expression is log2(edgeR normalised expression) going from low (blue) to high (red). None of the S. sclerotiorum genes homologous to yeast HOG pathway genes were significantly differentially expressed in either F4 or F5. c Expression of genes downstream of transcriptional regulators from the HOG pathway. Seven genes in S. sclerotiorum were differentially expressed in F4 and F5 and were homologous to S. cerevisiae genes known to be regulated by HOG pathway associated genes. These genes are known to be regulated by HOG1 and TUP1