Exploring genetic resistance to infectious salmon anaemia virus in Atlantic salmon by genome-wide association and RNA sequencing

Table 2 Selected KEGG pathways identified as enriched among differentially expressed genes

7 dpi
Up-regulated			Down-regulated
KEGG	N	FE	p	KEGG	N	FE	p
Carbon metabolism	83	6.01	10⁻¹⁶	Complement and coagulation cascades	23	2.73	0.002
Aminoacyl-tRNA biosynthesis	39	2.98	10⁻¹³	FoxO signalling pathway	36	1.90	0.010
Citrate cycle (TCA cycle)	38	2.27	10⁻¹¹	HTLV-I infection	50	1.67	0.012
14 dpi
Up-regulated			Down-regulated
KEGG	N	FE	p	KEGG	N	FE	p
Carbon metabolism	75	9.31	10⁻³⁰	Complement and coagulation cascades	57	12.76	10^− 36
Glycolysis / gluconeogenesis	31	4.50	10⁻¹¹	Staphylococcus aureus infection	24	5.31	10⁻¹⁵
Biosynthesis of amino acids	35	6.99	10⁻¹⁰	Systemic lupus erythematosus	17	7.17	10⁻⁵

KEGG KEGG pathway, N Number of genes differentially expressed assigned to the corresponding KEGG pathway, FE Fold enrichment, p False discovery rate corrected p-value.

ISSN: 1471-2164