Fig. 3From: Integrated proteomic and transcriptomic profiling identifies aberrant gene and protein expression in the sarcomere, mitochondrial complex I, and the extracellular matrix in Warmblood horses with myofibrillar myopathyA. Normal appearing myofibrils adjacent to myofibrils with Z-disc disruption (arrow) and myofilament disarray in an MFM WB. 10 k. B. Marked myofilament disarray and ectopic accumulation of Z-disc material in an MFM WB. 10 k. C. Higher magnification of B. highlighting Z disc protein aggregation (arrow). 40 k. D. Mitochondria showing variability in size and cristae formation in an MFM WB. 27 kBack to article page