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Table 2 Gene Ontology analysis based on differential expression. The results for the top 10 processes are shown in the table

From: Transcriptomic coordination at hepatic steatosis indicates robust immune cell engagement prior to inflammation

GO biological process complete Fold Enrichment raw P-value FDR
Steatosis vs Control
 actomyosin contractile ring organization (GO:0044837) 25.52 6.19E-04 2.21E-02
 actomyosin contractile ring assembly (GO:0000915) 25.52 6.19E-04 2.20E-02
 assembly of actomyosin apparatus involved in cytokinesis (GO:0000912) 25.52 6.19E-04 2.20E-02
 regulation of postsynaptic cytosolic calcium ion concentration (GO:0099566) 25.52 6.19E-04 2.19E-02
 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905007) 25.52 6.19E-04 2.19E-02
 negative regulation of lipoprotein lipase activity (GO:0051005) 24.3 7.99E-05 4.58E-03
 glomerular visceral epithelial cell migration (GO:0090521) 21.26 9.13E-04 2.88E-02
 mitotic spindle midzone assembly (GO:0051256) 21.26 9.13E-04 2.88E-02
 mitotic spindle elongation (GO:0000022) 21.26 9.13E-04 2.87E-02
 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905005) 21.26 9.13E-04 2.86E-02
Non steatosis vs Control
 regulation of intestinal cholesterol absorption (GO:0030300) >  100 2.85E-06 8.98E-03
 regulation of intestinal lipid absorption (GO:1904729) >  100 3.56E-06 8.01E-03
 regulation of intestinal absorption (GO:1904478) 91.62 7.54E-06 1.48E-02
 positive regulation of fatty acid biosynthetic process (GO:0045723) 56.38 2.80E-05 3.15E-02
 positive regulation of triglyceride metabolic process (GO:0090208) 50.55 3.79E-05 3.73E-02
 positive regulation of lipid catabolic process (GO:0050996) 47.29 4.56E-05 4.22E-02
 positive regulation of fatty acid metabolic process (GO:0045923) 42.49 3.26E-06 8.57E-03
 regulation of fatty acid metabolic process (GO:0019217) 20.57 4.96E-05 4.34E-02
 steroid biosynthetic process (GO:0006694) 19.94 5.57E-05 4.62E-02
 monocarboxylic acid biosynthetic process (GO:0072330) 16.4 1.52E-05 2.18E-02
Steatosis vs Non-Steatosis
 positive regulation of phagocytosis, engulfment (GO:0060100) 16 3 0.05
 positive regulation of membrane invagination (GO:1905155) 16 3 0.05
 animal organ regeneration (GO:0031100) 27 4 0.09
 regeneration (GO:0031099) 101 5 0.34
 regulation of cell death (GO:0010941) 1667 20 5.53
 regulation of programmed cell death (GO:0043067) 1504 18 4.99
 regulation of apoptotic process (GO:0042981) 1468 17 4.87
 regulation of cell population proliferation (GO:0042127) 1691 18 5.61
 cellular response to organic substance (GO:0071310) 1816 18 6.03
 response to organic substance (GO:0010033) 2529 22 8.4