Table 2 Gene Ontology analysis based on differential expression. The results for the top 10 processes are shown in the table
GO biological process complete | Fold Enrichment | raw P-value | FDR |
|---|---|---|---|
Steatosis vs Control | |||
 actomyosin contractile ring organization (GO:0044837) | 25.52 | 6.19E-04 | 2.21E-02 |
 actomyosin contractile ring assembly (GO:0000915) | 25.52 | 6.19E-04 | 2.20E-02 |
 assembly of actomyosin apparatus involved in cytokinesis (GO:0000912) | 25.52 | 6.19E-04 | 2.20E-02 |
 regulation of postsynaptic cytosolic calcium ion concentration (GO:0099566) | 25.52 | 6.19E-04 | 2.19E-02 |
 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905007) | 25.52 | 6.19E-04 | 2.19E-02 |
 negative regulation of lipoprotein lipase activity (GO:0051005) | 24.3 | 7.99E-05 | 4.58E-03 |
 glomerular visceral epithelial cell migration (GO:0090521) | 21.26 | 9.13E-04 | 2.88E-02 |
 mitotic spindle midzone assembly (GO:0051256) | 21.26 | 9.13E-04 | 2.88E-02 |
 mitotic spindle elongation (GO:0000022) | 21.26 | 9.13E-04 | 2.87E-02 |
 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905005) | 21.26 | 9.13E-04 | 2.86E-02 |
Non steatosis vs Control | |||
 regulation of intestinal cholesterol absorption (GO:0030300) | >  100 | 2.85E-06 | 8.98E-03 |
 regulation of intestinal lipid absorption (GO:1904729) | >  100 | 3.56E-06 | 8.01E-03 |
 regulation of intestinal absorption (GO:1904478) | 91.62 | 7.54E-06 | 1.48E-02 |
 positive regulation of fatty acid biosynthetic process (GO:0045723) | 56.38 | 2.80E-05 | 3.15E-02 |
 positive regulation of triglyceride metabolic process (GO:0090208) | 50.55 | 3.79E-05 | 3.73E-02 |
 positive regulation of lipid catabolic process (GO:0050996) | 47.29 | 4.56E-05 | 4.22E-02 |
 positive regulation of fatty acid metabolic process (GO:0045923) | 42.49 | 3.26E-06 | 8.57E-03 |
 regulation of fatty acid metabolic process (GO:0019217) | 20.57 | 4.96E-05 | 4.34E-02 |
 steroid biosynthetic process (GO:0006694) | 19.94 | 5.57E-05 | 4.62E-02 |
 monocarboxylic acid biosynthetic process (GO:0072330) | 16.4 | 1.52E-05 | 2.18E-02 |
Steatosis vs Non-Steatosis | |||
 positive regulation of phagocytosis, engulfment (GO:0060100) | 16 | 3 | 0.05 |
 positive regulation of membrane invagination (GO:1905155) | 16 | 3 | 0.05 |
 animal organ regeneration (GO:0031100) | 27 | 4 | 0.09 |
 regeneration (GO:0031099) | 101 | 5 | 0.34 |
 regulation of cell death (GO:0010941) | 1667 | 20 | 5.53 |
 regulation of programmed cell death (GO:0043067) | 1504 | 18 | 4.99 |
 regulation of apoptotic process (GO:0042981) | 1468 | 17 | 4.87 |
 regulation of cell population proliferation (GO:0042127) | 1691 | 18 | 5.61 |
 cellular response to organic substance (GO:0071310) | 1816 | 18 | 6.03 |
 response to organic substance (GO:0010033) | 2529 | 22 | 8.4 |