Skip to main content

Table 4 Genes that showed significant association across all quarantine nursery traits in single-gene association analysis (q < 0.20)

From: Quantitative analysis of the blood transcriptome of young healthy pigs and its relationship with subsequent disease resilience

Gene

  

Quarantine nursery traits

 

Ensembl ID

Symbol

GO term of the direct biological process

Health

score 1

Health

score 2

Growth

rate

Resilience

ENSSSCG00000003586

EPB41

blood circulation

WO+

BOTH+

BOTH+

 

ENSSSCG00000008820

TEC

innate and adaptive immune response

WO-

WO-

BOTH-

 

ENSSSCG00000009002

TLR2

inflammatory response, immune response

WO-

WO-

BOTH-

FCRWO+

ENSSSCG00000010025

LIMK2

spermatogenesis

WO-

WO-

BOTH-

 

ENSSSCG00000010445

ANKRD22

–

WO-

WO-

BOTH-

 

ENSSSCG00000012880

CPT1A

regulation of insulin secretion, eating behavior

BOTH-

WO-

BOTH-

 

ENSSSCG00000013065

ASRGL1

proteolysis

WO-

WO-

BOTH-

FCRWO+

ENSSSCG00000013556

ADGRE1

adaptive immune response

WO-

WO-

BOTH-

 

ENSSSCG00000017126

NARF

–

WO+

BOTH+

BOTH+

 

ENSSSCG00000020872

–

–

BOTH+

BOTH+

BOTH+

LYLD WO+

ENSSSCG00000033146

CD163

acute-phase response, viral entry into host cell

WO-

WO-

BOTH-

NurMTBOTH-AllMORWO-

ENSSSCG00000033190

–

–

WO+

BOTH+

BOTH+

 

ENSSSCG00000033703

FAM111A

defense response to virus

WO-

WO-

BOTH-

NurMTBOTH-FCRWO+

ENSSSCG00000035182

SDR42E1

steroid biosynthetic process

WO-

WO-

BOTH-

 
  1. Abbreviation: WO and WI, the significant association (q < 0.20) between observed phenotypes and gene expression levels with or without accounting for with blood cell composition, respectively; BOTH, the significant associations of both expressions with and without accounting for blood cell composition, with observed phenotypes; + and -, the favorable and unfavorable direction of relationship with observed phenotypes, respectively; FCR, feed conversion rate; LYLD, lean yield; NurMT, mortality with treatment during challenge nursery; AllMOR, mortality across whole period