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Table 4 Genes that showed significant association across all quarantine nursery traits in single-gene association analysis (q < 0.20)

From: Quantitative analysis of the blood transcriptome of young healthy pigs and its relationship with subsequent disease resilience

Gene    Quarantine nursery traits  
Ensembl ID Symbol GO term of the direct biological process Health
score 1
Health
score 2
Growth
rate
Resilience
ENSSSCG00000003586 EPB41 blood circulation WO+ BOTH+ BOTH+  
ENSSSCG00000008820 TEC innate and adaptive immune response WO- WO- BOTH-  
ENSSSCG00000009002 TLR2 inflammatory response, immune response WO- WO- BOTH- FCRWO+
ENSSSCG00000010025 LIMK2 spermatogenesis WO- WO- BOTH-  
ENSSSCG00000010445 ANKRD22 WO- WO- BOTH-  
ENSSSCG00000012880 CPT1A regulation of insulin secretion, eating behavior BOTH- WO- BOTH-  
ENSSSCG00000013065 ASRGL1 proteolysis WO- WO- BOTH- FCRWO+
ENSSSCG00000013556 ADGRE1 adaptive immune response WO- WO- BOTH-  
ENSSSCG00000017126 NARF WO+ BOTH+ BOTH+  
ENSSSCG00000020872 BOTH+ BOTH+ BOTH+ LYLD WO+
ENSSSCG00000033146 CD163 acute-phase response, viral entry into host cell WO- WO- BOTH- NurMTBOTH-AllMORWO-
ENSSSCG00000033190 WO+ BOTH+ BOTH+  
ENSSSCG00000033703 FAM111A defense response to virus WO- WO- BOTH- NurMTBOTH-FCRWO+
ENSSSCG00000035182 SDR42E1 steroid biosynthetic process WO- WO- BOTH-  
  1. Abbreviation: WO and WI, the significant association (q < 0.20) between observed phenotypes and gene expression levels with or without accounting for with blood cell composition, respectively; BOTH, the significant associations of both expressions with and without accounting for blood cell composition, with observed phenotypes; + and -, the favorable and unfavorable direction of relationship with observed phenotypes, respectively; FCR, feed conversion rate; LYLD, lean yield; NurMT, mortality with treatment during challenge nursery; AllMOR, mortality across whole period