Oxford Nanopore and Bionano Genomics technologies evaluation for plant structural variation detection

BMC Genomics

Table 5 Summary of comparisons of ONT assembly and Bionano Optical mapping (DLS labeling) for SV detection

Technology	ONT	Bionano
Assembly/Optical map obtention	√√	√√
1 kb < SV < 50 kb
Deletion	√√	√
Insertion	√√	√
Inversion	√	√√
Translocation	NA	√
SV > 50 kb
Deletion	√	√√
Insertion	√	√√
Inversion	–	√√
Translocation	NA	√√
SV location
Genic	√√	√√
Complex	√	√√
Acces to the SV sequence	√√	NA
Bioinformatic skills	√	√√
SV visualization	√	√√

√√ Robust detection or user friendly. √ Detection depending on variables such as coverage, contig length and label density or need of bioinformatic skills. NA: Not available; − Undetectable

ISSN: 1471-2164