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Table 5 Summary of comparisons of ONT assembly and Bionano Optical mapping (DLS labeling) for SV detection

From: Oxford Nanopore and Bionano Genomics technologies evaluation for plant structural variation detection

Technology ONT Bionano
Assembly/Optical map obtention √√ √√
1 kb < SV < 50 kb
 Deletion √√
 Insertion √√
 Inversion √√
 Translocation NA
SV > 50 kb
 Deletion √√
 Insertion √√
 Inversion √√
 Translocation NA √√
SV location
 Genic √√ √√
 Complex √√
Acces to the SV sequence √√ NA
Bioinformatic skills √√
SV visualization √√
  1. √√ Robust detection or user friendly. √ Detection depending on variables such as coverage, contig length and label density or need of bioinformatic skills. NA: Not available; − Undetectable