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Fig. 2 | BMC Genomics

Fig. 2

From: A recurrent somatic missense mutation in GNAS gene identified in familial thyroid follicular cell carcinomas in German longhaired pointer dogs

Fig. 2

A. comparison of number of mutations identified in CDS region between canine tumors and 3 types of human thyroid tumors. Abbreviations: c.FCC – canine follicular cell carcinoma, h.TC – human papillary thyroid carcinoma (from TCGA project), h.FTA – human follicular thyroid adenoma, h.FTC – human follicular thyroid carcinoma. B. Mutation landscape of the 7 tumors. Each column represents one sample, each row represents one somatic mutated gene. The right bar chart represents the frequencies of gene alterations across the 7 tumors. The upper bar chart represents the number of mutation in exons across the 7 tumors. C. Number of somatic SNVs and Indels identified in 4 tumors with the GNAS p.A204D mutation (GNAS-mut) and 3 samples without that somatic mutation (GNAS-wild)

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BMC Genomics

ISSN: 1471-2164

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