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Table 1 Effect of different concentrations of 10,058-F4 on the developmental competence of porcine embryo

From: Profiling the transcriptomic signatures and identifying the patterns of zygotic genome activation – a comparative analysis between early porcine embryos and their counterparts in other three mammalian species

10,058-F4 Treatment (uM)

No. of embryos

No. of embryos cleaved (% ± SEM)

No. of blastocysts (% ± SEM)

0

150

76(50.8 ± 1.34)A

51(34.0 ± 0.21)A

0.5 uM

145

72(49.7 ± 1.58)B

47(32.4 ± 1.94)A

1 uM

150

57(38.0 ± 2.34)B

35(23.3 ± 1.31)B

2.5 uM

150

50(33.3 ± 0.17)C

38(25.3 ± 2.47)B

5 uM

155

63(40.6 ± 2.09)B

46(29.7 ± 2.11)B

7.5 uM

155

48(30.9 ± 1.12)C

38(24.5 ± 0.45)B

10 uM

150

48(32.0 ± 0.91)C

31(20.7 ± 1.71)B

25 uM

150

47(31.3 ± 2.21)C

25(16.7 ± 2.19)C

50 uM

150

32(21.3 ± 1.41)D

8(5.3 ± 0.98)D

100 uM

140

0(0.0 ± 0.00)E

0(0.0 ± 0.00)E

  1. Values in the same column with different superscripts from A to E differ significantly (P < 0.05)