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Fig. 1 | BMC Genomics

Fig. 1

From: Identification of biomarkers and therapeutic targets related to Sepsis-associated encephalopathy in rats by quantitative proteomics

Fig. 1

The experimental workflow. Firstly, the Prague-Dawley rats were randomly divided into sepsis (n = 6) or sham (n = 6) groups, and then the whole brain tissue was dissected at 24 h after surgery for further protein identification by Quantitative iTRAQ LC-MS/MS Proteomics. Secondly, Ingenuity pathway analysis, Gene ontology knowledgebase, and STRING database are used to explore the biological significance of the differentially abundant proteins. At last, Western blot was performed to validate the concentration of GC, Akt1, and ApoA1.

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BMC Genomics

ISSN: 1471-2164

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