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Volume 12 Supplement 4

Proceedings of the 6th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-meeting 2010)

Proceedings

Edited by RAP Nagem (Co-ordinating Editor), AM Durham, ATR Vasconcelos, CB Monteiro-Vitorello, E Dias-Neto, GB Domont, GC Oliveira, L Felicori, L Bleicher, JM Ortega, MS Skaf, O Norberto de Souza, PR Kuser-Falcão, R Guerra-Sá, R DeMarco, TM Venancio and T Koide

The organizers would like to thank the following agencies for their financial support of the conference: CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico) and FAPEMIG (Fundação de Amparo à Pesquisa do Estado de Minas Gerais).

6th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-meeting 2010). Go to conference site.

Ouro Preto, Brazil15-18 November 2010

  1. Biological systems are commonly described as networks of entity interactions. Some interactions are already known and integrate the current knowledge in life sciences. Others remain unknown for long periods of...

    Authors: Wesley D Maciel, Alessandra C Faria-Campos, Marcos A Gonçalves and Sérgio VA Campos
    Citation: BMC Genomics 2011 12(Suppl 4):S1
  2. Besides being building blocks for proteins, amino acids are also key metabolic intermediates in living cells. Surprisingly a variety of organisms are incapable of synthesizing some of them, thus named Essentia...

    Authors: RLM Guedes, F Prosdocimi, GR Fernandes, LK Moura, HAL Ribeiro and JM Ortega
    Citation: BMC Genomics 2011 12(Suppl 4):S2
  3. The integration of sequencing and gene interaction data and subsequent generation of pathways and networks contained in databases such as KEGG Pathway is essential for the comprehension of complex biological p...

    Authors: Elisa Donnard, Adriano Barbosa-Silva, Rafael LM Guedes, Gabriel R Fernandes, Henrique Velloso, Matthew J Kohn, Miguel A Andrade-Navarro and J Miguel Ortega
    Citation: BMC Genomics 2011 12(Suppl 4):S3
  4. Microalgae have the potential to deliver biofuels without the associated competition for land resources. In order to realise the rates and titres necessary for commercial production, however, system-level meta...

    Authors: Cristiana Gomes de Oliveira Dal’Molin, Lake-Ee Quek, Robin W Palfreyman and Lars K Nielsen
    Citation: BMC Genomics 2011 12(Suppl 4):S5
  5. In silico molecular docking is an essential step in modern drug discovery when driven by a well defined macromolecular target. Hence, the process is called structure-based or rational drug design (RDD). In the do...

    Authors: Karina S Machado, Evelyn K Schroeder, Duncan D Ruiz, Elisângela ML Cohen and Osmar Norberto de Souza
    Citation: BMC Genomics 2011 12(Suppl 4):S6
  6. Protein/receptor explicit flexibility has recently become an important feature of molecular docking simulations. Taking the flexibility into account brings the docking simulation closer to the receptors’ real ...

    Authors: Elisangela ML Cohen, Karina S Machado, Marcelo Cohen and Osmar Norberto de Souza
    Citation: BMC Genomics 2011 12(Suppl 4):S7
  7. Aquaporins are a large family of transmembrane channel proteins that are present throughout all domains of life and are implicated in human disorders. These channels, allow the passive but selective movement o...

    Authors: Raul Araya-Secchi, JA Garate, David S Holmes and Tomas Perez-Acle
    Citation: BMC Genomics 2011 12(Suppl 4):S8
  8. The accurate prediction of the initiation of translation in sequences of mRNA is an important activity for genome annotation. However, obtaining an accurate prediction is not always a simple task and can be mo...

    Authors: Lívia Márcia Silva, Felipe Carvalho de Souza Teixeira, José Miguel Ortega, Luis Enrique Zárate and Cristiane Neri Nobre
    Citation: BMC Genomics 2011 12(Suppl 4):S9
  9. We introduce a method to analyze the states of regulatory Boolean models that identifies important network states and their biological influence on the global network dynamics. It consists in (1) finding the s...

    Authors: Cristhian A Bugs, Giovani R Librelotto and José CM Mombach
    Citation: BMC Genomics 2011 12(Suppl 4):S10
  10. Singular value decomposition (SVD) is a powerful technique for information retrieval; it helps uncover relationships between elements that are not prima facie related. SVD was initially developed to reduce the ti...

    Authors: Anderson R Santos, Marcos A Santos, Jan Baumbach, John A McCulloch, Guilherme C Oliveira, Artur Silva, Anderson Miyoshi and Vasco Azevedo
    Citation: BMC Genomics 2011 12(Suppl 4):S11
  11. The unforgiving pace of growth of available biological data has increased the demand for efficient and scalable paradigms, models and methodologies for automatic annotation. In this paper, we present a novel s...

    Authors: Douglas EV Pires, Raquel C de Melo-Minardi, Marcos A dos Santos, Carlos H da Silveira, Marcelo M Santoro and Wagner Meira Jr.
    Citation: BMC Genomics 2011 12(Suppl 4):S12
  12. Recent medical and biological technology advances have stimulated the development of new testing systems that have been providing huge, varied amounts of molecular and clinical data. Growing data volumes pose ...

    Authors: Luciano V Araújo, Simon Malkowski, Kelly R Braghetto, Maria R Passos-Bueno, Mayana Zatz, Calton Pu and João E Ferreira
    Citation: BMC Genomics 2011 12(Suppl 4):S13
  13. A research area that has greatly benefited from the development of new and improved analysis technologies is Proteomics and large amounts of data have been generated by proteomic analysis as a consequence. Pre...

    Authors: Alessandra Faria-Campos, Herbert Fernandes-Rausch, Celina Val, Peter Thorun, Vinicius Abreu, Paulo Henrique Batista, Paulo Henrique Mendonça, Vinicius Alves, Maíra Ribeiro Rodrigues, Adriano Pimenta, Glória Franco and Sérgio Vale Aguiar Campos
    Citation: BMC Genomics 2011 12(Suppl 4):S15

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