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Volume 13 Supplement 7

Eleventh International Conference on Bioinformatics (InCoB2012): Computational Biology


Edited by Shoba Ranganathan, Christian Schönbach, Sissades Tongsima, Jonathan Chan and Tin Wee Tan

The articles in this supplement were supported by funding agencies as detailed in the Acknowledgement section of each article

Asia Pacific Bioinformatics Network (APBioNet) Eleventh International Conference on Bioinformatics (InCoB2012). Go to conference site.

Bangkok, Thailand3-5 October 2012

  1. The theme of the 2012 International Conference on Bioinformatics (InCoB) in Bangkok, Thailand was "From Biological Data to Knowledge to Technological Breakthroughs." Besides providing a forum for life scientis...

    Authors: Shoba Ranganathan, Sissades Tongsima, Jonathan Chan, Tin Wee Tan and Christian Schönbach
    Citation: BMC Genomics 2012 13(Suppl 7):S1
  2. Genome-wide association studies (GWAS) do not provide a full account of the heritability of genetic diseases since gene-gene interactions, also known as epistasis are not considered in single locus GWAS. To ad...

    Authors: Jittima Piriyapongsa, Chumpol Ngamphiw, Apichart Intarapanich, Supasak Kulawonganunchai, Anunchai Assawamakin, Chaiwat Bootchai, Philip J Shaw and Sissades Tongsima
    Citation: BMC Genomics 2012 13(Suppl 7):S2
  3. The preferred habitat of a given bacterium can provide a hint of which types of enzymes of potential industrial interest it might produce. These might include enzymes that are stable and active at very high or...

    Authors: Dan B Jensen, Tammi C Vesth, Peter F Hallin, Anders G Pedersen and David W Ussery
    Citation: BMC Genomics 2012 13(Suppl 7):S3
  4. The opportunistic enterobacterium, Morganella morganii, which can cause bacteraemia, is the ninth most prevalent cause of clinical infections in patients at Changhua Christian Hospital, Taiwan. The KT strain of M...

    Authors: Yu-Tin Chen, Hwei-Ling Peng, Wei-Chung Shia, Fang-Rong Hsu, Chuian-Fu Ken, Yu-Ming Tsao, Chang-Hua Chen, Chun-Eng Liu, Ming-Feng Hsieh, Huang-Chi Chen, Chuan-Yi Tang and Tien-Hsiung Ku
    Citation: BMC Genomics 2012 13(Suppl 7):S4
  5. Mitochondrial dysfunction is associated with various aging diseases. The copy number of mtDNA in human cells may therefore be a potential biomarker for diagnostics of aging. Here we propose a new computational...

    Authors: Hsueh-Ting Chu, William WL Hsiao, Theresa TH Tsao, Ching-Mao Chang, Yen-Wenn Liu, Chen-Chieh Fan, Han Lin, Hen-Hong Chang, Tze-Jung Yeh, Jen-Chih Chen, Dun-Ming Huang, Chaur-Chin Chen and Cheng-Yan Kao
    Citation: BMC Genomics 2012 13(Suppl 7):S5
  6. The advances and decreasing economical cost of whole genome sequencing (WGS), will soon make this technology available for routine infectious disease epidemiology. In epidemiological studies, outbreak isolates...

    Authors: Pimlapas Leekitcharoenphon, Rolf S Kaas, Martin Christen Frølund Thomsen, Carsten Friis, Simon Rasmussen and Frank M Aarestrup
    Citation: BMC Genomics 2012 13(Suppl 7):S6
  7. Dengue is the world's most common mosquito-borne viral disease. Poor proofreading by RNA polymerase during its replication results in the accumulation of mutations in its genome. This leads to a diversity of g...

    Authors: Kwanrutai Chin-inmanu, Aroonroong Suttitheptumrong, Duangjai Sangsrakru, Sithichoke Tangphatsornruang, Somvong Tragoonrung, Prida Malasit, Sumalee Tungpradabkul and Prapat Suriyaphol
    Citation: BMC Genomics 2012 13(Suppl 7):S7
  8. Helminths are important socio-economic organisms, responsible for causing major parasitic infections in humans, other animals and plants. These infections impose a significant public health and economic burden...

    Authors: Gagan Garg and Shoba Ranganathan
    Citation: BMC Genomics 2012 13(Suppl 7):S8
  9. Recent developments in high-throughput sequencing (HTS) technologies have made it feasible to sequence the complete transcriptomes of non-model organisms or metatranscriptomes from environmental samples. The c...

    Authors: Ting-Wen Chen, Ruei-Chi Richie Gan, Timothy H Wu, Po-Jung Huang, Cheng-Yang Lee, Yi-Ywan M Chen, Che-Chun Chen and Petrus Tang
    Citation: BMC Genomics 2012 13(Suppl 7):S9
  10. Teladorsagia circumcincta (order Strongylida) is an economically important parasitic nematode of small ruminants (including sheep and goats) in temperate climatic regions of the world. Improved insights into the ...

    Authors: Ranjeeta Menon, Robin B Gasser, Makedonka Mitreva and Shoba Ranganathan
    Citation: BMC Genomics 2012 13(Suppl 7):S10
  11. Multiple transcription factors (TFs) are involved in the generation of gene expression patterns, such as tissue-specific gene expression and pleiotropic immune responses. However, how combinations of TFs orche...

    Authors: Alexis Vandenbon, Yutaro Kumagai, Shizuo Akira and Daron M Standley
    Citation: BMC Genomics 2012 13(Suppl 7):S11
  12. Researches have been conducted for the identification of differentially expressed genes (DEGs) by generating and mining of cDNA expressed sequence tags (ESTs) for more than a decade. Although the availability ...

    Authors: Timothy H Wu, Lichieh J Chu, Jian-Chiao Wang, Ting-Wen Chen, Yin-Jing Tien, Wen-Chang Lin and Wailap V Ng
    Citation: BMC Genomics 2012 13(Suppl 7):S12
  13. The sRNAs of bacterial pathogens are known to be involved in various cellular roles including environmental adaptation as well as regulation of virulence and pathogenicity. It is expected that sRNAs may also h...

    Authors: Jia-Shiun Khoo, Shiao-Fei Chai, Rahmah Mohamed, Sheila Nathan and Mohd Firdaus-Raih
    Citation: BMC Genomics 2012 13(Suppl 7):S13
  14. MicroRNAs (miRNAs) are a class of small noncoding RNAs that regulate the target gene expression at post-transcriptional level. They are widely involved in biological processes, such as embryonic development, c...

    Authors: Zhen Yang, Dong Dong, Zhaolei Zhang, M James C Crabbe, Li Wang and Yang Zhong
    Citation: BMC Genomics 2012 13(Suppl 7):S14
  15. The microRNA-based gene-silencing machinery has been recognized as a promising approach to control viral replication and used for improving safety for the live attenuated virus vaccines. The effective host mic...

    Authors: Duangdao Wichadakul, Wuttichai Mhuantong, Anan Jongkaewwattana and Supawadee Ingsriswang
    Citation: BMC Genomics 2012 13(Suppl 7):S15
  16. MicroRNAs (miRNAs) have been known to play an important role in several biological processes in both animals and plants. Although several tools for miRNA and target identification are available, the number of ...

    Authors: Somrak Numnark, Wuttichai Mhuantong, Supawadee Ingsriswang and Duangdao Wichadakul
    Citation: BMC Genomics 2012 13(Suppl 7):S16
  17. Functional annotations are available only for a very small fraction of microRNAs (miRNAs) and very few miRNA target genes are experimentally validated. Therefore, functional analysis of miRNA clusters has typi...

    Authors: Su Yeon Lee, Kyung-Ah Sohn and Ju Han Kim
    Citation: BMC Genomics 2012 13(Suppl 7):S17
  18. MicroRNAs (miRNAs) are short noncoding RNAs (approximately 22 nucleotides in length) that play important roles in breast cancer progression by downregulating gene expression. The detailed mechanisms and biolog...

    Authors: Hong-Tai Chang, Sung-Chou Li, Meng-Ru Ho, Hung-Wei Pan, Luo-Ping Ger, Ling-Yueh Hu, Shou-Yu Yu, Wen-Hsiung Li and Kuo-Wang Tsai
    Citation: BMC Genomics 2012 13(Suppl 7):S18
  19. Leishmaniasis is caused by several species of leishmania protozoan and is one of the major vector-born diseases after malaria and sleeping sickness. Toxicity of available drugs and drug resistance development ...

    Authors: Abhinav Grover, Shashank Prakash Katiyar, Jeyaraman Jeyakanthan, Vikash Kumar Dubey and Durai Sundar
    Citation: BMC Genomics 2012 13(Suppl 7):S20
  20. To discover a compound inhibiting multiple proteins (i.e. polypharmacological targets) is a new paradigm for the complex diseases (e.g. cancers and diabetes). In general, the polypharmacological proteins often...

    Authors: Yi-Yuan Chiu, Chun-Yu Lin, Chih-Ta Lin, Kai-Cheng Hsu, Li-Zen Chang and Jinn-Moon Yang
    Citation: BMC Genomics 2012 13(Suppl 7):S21
  21. Molecular chaperones appear to have been evolved to facilitate protein folding in the cell through entrapment of folding intermediates on the interior of a large cavity formed between GroEL and its co-chaperon...

    Authors: Vipul Kumar, Ankita Punetha, Durai Sundar and Tapan K Chaudhuri
    Citation: BMC Genomics 2012 13(Suppl 7):S22
  22. The overwhelming amount of network data in functional genomics is making its visualization cluttered with jumbling nodes and edges. Such cluttered network visualization, which is known as "hair-balls", is sign...

    Authors: Thanet Praneenararat, Toshihisa Takagi and Wataru Iwasaki
    Citation: BMC Genomics 2012 13(Suppl 7):S24
  23. State-of-the-art high-throughput sequencers, e.g., the Illumina HiSeq series, generate sequencing reads that are longer than 150 bp up to a total of 600 Gbp of data per run. The high-throughput sequencers gene...

    Authors: Yu-Jung Chang, Chien-Chih Chen, Chuen-Liang Chen and Jan-Ming Ho
    Citation: BMC Genomics 2012 13(Suppl 7):S28
  24. Tha Wang and Tham Phang coasts, though situated at similar oceanographic positions on Sichang island, Chonburi province, Thailand, are different in bay geography and amount of municipal disturbances. These aff...

    Authors: Naraporn Somboonna, Anunchai Assawamakin, Alisa Wilantho, Sithichoke Tangphatsornruang and Sissades Tongsima
    Citation: BMC Genomics 2012 13(Suppl 7):S29

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