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Volume 18 Supplement 6

Selected articles from the International Conference on Intelligent Biology and Medicine (ICIBM) 2016: genomics


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Houston, TX, USA08-10 December 2016

Conference website

Edited by Zhongming Zhao, Jianhua Ruan, W. Jim Zheng and Zhandong Liu

Related articles have been published in supplements to BMC Bioinformatics, BMC Medical Genomics and BMC Systems Biology.

  1. In this editorial, we first summarize the 2016 International Conference on Intelligent Biology and Medicine (ICIBM 2016) that was held on December 8–10, 2016 in Houston, Texas, USA, and then briefly introduce ...

    Authors: Zhongming Zhao, Zhandong Liu, Ken Chen, Yan Guo, Genevera I. Allen, Jiajie Zhang, W. Jim Zheng and Jianhua Ruan
    Citation: BMC Genomics 2017 18(Suppl 6):703
  2. Characterization of genomic structural variation (SV) is essential to expanding the research and clinical applications of genome sequencing. Reliance upon short DNA fragment paired end sequencing has yielded a...

    Authors: Oliver A. Hampton, Adam C. English, Mark Wang, William J. Salerno, Yue Liu, Donna M. Muzny, Yi Han, David A. Wheeler, Kim C. Worley, James R. Lupski and Richard A. Gibbs
    Citation: BMC Genomics 2017 18(Suppl 6):691
  3. High throughput sequencing technology enables the both the human genome and transcriptome to be screened at the single nucleotide resolution. Tools have been developed to infer single nucleotide variants (SNVs...

    Authors: Yan Guo, Shilin Zhao, Quanhu Sheng, David C Samuels and Yu Shyr
    Citation: BMC Genomics 2017 18(Suppl 6):690
  4. The ability to predict epitopes plays an enormous role in vaccine development in terms of our ability to zero in on where to do a more thorough in-vivo analysis of the protein in question. Though for the past ...

    Authors: Gene Sher, Degui Zhi and Shaojie Zhang
    Citation: BMC Genomics 2017 18(Suppl 6):676
  5. Flux Balance Analysis (FBA) based mathematical modeling enables in silico prediction of systems behavior for genome-scale metabolic networks. Computational methods have been derived in the FBA framework to solve ...

    Authors: Meltem Apaydin, Liang Xu, Bo Zeng and Xiaoning Qian
    Citation: BMC Genomics 2017 18(Suppl 6):677
  6. In 2016, it is estimated that there will be 62,700 new cases of kidney cancer in the United States, and 14,240 patients will die from the disease. Because the incidence of kidney renal clear cell carcinoma (KI...

    Authors: Guangchun Han, Wei Zhao, Xiaofeng Song, Patrick Kwok-Shing Ng, Jose A. Karam, Eric Jonasch, Gordon B. Mills, Zhongming Zhao, Zhiyong Ding and Peilin Jia
    Citation: BMC Genomics 2017 18(Suppl 6):678
  7. High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively ...

    Authors: Vladimir A. Kuznetsov, Zhiqun Tang and Anna V. Ivshina
    Citation: BMC Genomics 2017 18(Suppl 6):692
  8. With the advances in high-throughput gene profiling technologies, a large volume of gene interaction maps has been constructed. A higher-level layer of gene-gene interaction, namely modulate gene interaction, ...

    Authors: Yu-Chiao Chiu, Li-Ju Wang, Tzu-Hung Hsiao, Eric Y. Chuang and Yidong Chen
    Citation: BMC Genomics 2017 18(Suppl 6):679
  9. Circular RNA (circRNA) is one type of noncoding RNA that forms a covalently closed continuous loop. Similar to long noncoding RNA (lncRNA), circRNA can act as microRNA (miRNA) ‘sponges’ to regulate gene expres...

    Authors: Tianyi Xu, Jing Wu, Ping Han, Zhongming Zhao and Xiaofeng Song
    Citation: BMC Genomics 2017 18(Suppl 6):680

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