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  1. The evolution of influenza A viruses leads to the antigenic changes. Serological diagnosis of the antigenicity is usually labor-intensive, time-consuming and not suitable for early-stage detection. Computation...

    Authors: Xinrui Zhou, Rui Yin, Chee-Keong Kwoh and Jie Zheng
    Citation: BMC Genomics 2018 19(Suppl 10):936

    This article is part of a Supplement: Volume 19 Supplement 10

  2. Interactions among transcription factors (TFs) and histone modifications (HMs) play an important role in the precise regulation of gene expression. The context specificity of those interactions and further its...

    Authors: Lirong Zhang, Gaogao Xue, Junjie Liu, Qianzhong Li and Yong Wang
    Citation: BMC Genomics 2018 19(Suppl 10):914

    This article is part of a Supplement: Volume 19 Supplement 10

  3. NGS data contains many machine-induced errors. The most advanced methods for the error correction heavily depend on the selection of solid k-mers. A solid k-mer is a k-mer frequently occurring in NGS reads. The o...

    Authors: Liang Zhao, Jin Xie, Lin Bai, Wen Chen, Mingju Wang, Zhonglei Zhang, Yiqi Wang, Zhe Zhao and Jinyan Li
    Citation: BMC Genomics 2018 19(Suppl 10):912

    This article is part of a Supplement: Volume 19 Supplement 10

  4. Human gut microbiome has an essential role in human health and disease. Although the major dominant microbiota within individuals have been reported, the change of gut microbiome caused by external factors, su...

    Authors: Hui-Mei Chen, Chung-Chu Chen, Chien-Chi Chen, Shen-Chih Wang, Chun-Lin Wang, Chien-Hsun Huang, Jong-Shian Liou, Ta-Wei Liu, Hwei-Ling Peng, Feng-Mao Lin, Chia-Yuan Liu, Shun-Long Weng, Chieh-Jen Cheng, Yi-Fang Hung, Chii-Cherng Liao and Hsien-Da Huang
    Citation: BMC Genomics 2018 19(Suppl 10):904

    This article is part of a Supplement: Volume 19 Supplement 10

  5. Proteins are a kind of macromolecules and the main component of a cell, and thus it is the most essential and versatile material of life. The research of protein functions is of great significance in decoding ...

    Authors: Lin Liu, Lin Tang, Mingjing Tang and Wei Zhou
    Citation: BMC Genomics 2018 19(Suppl 10):883

    This article is part of a Supplement: Volume 19 Supplement 10

  6. Species of Paris Sect. Marmorata are valuable medicinal plants to synthesize steroidal saponins with effective pharmacological therapy. However, the wild resources of the species are threatened by plundering expl...

    Authors: Xiaoyang Gao, Xuan Zhang, Honghu Meng, Jing Li, Di Zhang and Changning Liu
    Citation: BMC Genomics 2018 19(Suppl 10):878

    This article is part of a Supplement: Volume 19 Supplement 10

  7. Mud crabs, Scylla spp., are commercially important large-size marine crustaceans in the Indo-West Pacific region. As females have the higher growth rate and economic value, the production of all female stocks is ...

    Authors: Xi Shi, Khor Waiho, Xincang Li, Mhd Ikhwanuddin, Guidong Miao, Fan Lin, Yueling Zhang, Shengkang Li, Huaiping Zheng, Wenhua Liu, Jude Juventus Aweya, Ghazali Azmie, Juliana C. Baylon, Emilia T. Quinitio and Hongyu Ma
    Citation: BMC Genomics 2018 19:981
  8. The parthenogenetic Caucasian rock lizard Darevskia armeniaca, like most other parthenogenetic vertebrate species, originated through interspecific hybridization between the closely related sexual Darevskia mixta

    Authors: Anastasiya E. Girnyk, Andrey A. Vergun, Seraphima K. Semyenova, Andrei S. Guliaev, Marine S. Arakelyan, Felix D. Danielyan, Irena A. Martirosyan, Robert W. Murphy and Alexey P. Ryskov
    Citation: BMC Genomics 2018 19:979
  9. Dendrobium huoshanense C.Z. Tang et S.J. Cheng is a traditional Chinese herbal medicine with high medicinal value in China. Polysaccharides and alkaloids are its main active ingredients. To understand the differe...

    Authors: Yingdan Yuan, Maoyun Yu, Zhaohui Jia, Xue’er Song, Yingquan Liang and Jinchi Zhang
    Citation: BMC Genomics 2018 19:978
  10. Chloroplasts are organelles that conduct photosynthesis in plant and algal cells. The information chloroplast genome contained is widely used in agriculture and studies of evolution and ecology. Correctly asse...

    Authors: Weiwen Wang, Miriam Schalamun, Alejandro Morales-Suarez, David Kainer, Benjamin Schwessinger and Robert Lanfear
    Citation: BMC Genomics 2018 19:977
  11. Caleosin/peroxygenases, CLO/PXG, (designated PF05042 in Pfam) are a group of genes/proteins with anomalous distributions in eukaryotic taxa. We have previously characterised CLO/PXGs in the Viridiplantae. The aim...

    Authors: Farzana Rahman, Mehedi Hassan, Abdulsamie Hanano, David A. Fitzpatrick, Charley G. P. McCarthy and Denis J. Murphy
    Citation: BMC Genomics 2018 19:976
  12. MicroRNAs (miRNAs) are a class of small noncoding RNAs that play important roles in the regulation of gene expression. However, the role of miRNAs in bovine mammary gland responses to heat stress is not well u...

    Authors: Qiuling Li, Chunhong Yang, Juan Du, Baogui Zhang, Ying He, Qimeng Hu, Meiru Li, Yiming Zhang, Changfa Wang and Jifeng Zhong
    Citation: BMC Genomics 2018 19:975
  13. Numerous different types of variations can occur in DNA and have diverse effects and consequences. The Variation Ontology (VariO) was developed for systematic descriptions of variations and their effects at DN...

    Authors: Mauno Vihinen
    Citation: BMC Genomics 2018 19:974
  14. The ability of bacteria to acquire resistance to antibiotics relies to a large extent on their capacity for genome modification. Prokaryotic genomes are highly plastic and can utilize horizontal gene transfer,...

    Authors: Marloes Hoeksema, Martijs J. Jonker, Keshia Bel, Stanley Brul and Benno H. ter Kuile
    Citation: BMC Genomics 2018 19:973
  15. Paratuberculosis is a contagious, chronic and enteric disease in ruminants, which is caused by Mycobacterium avium subspecies paratuberculosis (MAP) infection, resulting in enormous economic losses worldwide. The...

    Authors: Yahui Gao, Jianping Jiang, Shaohua Yang, Jie Cao, Bo Han, Yachun Wang, Yi Zhang, Ying Yu, Shengli Zhang, Qin Zhang, Lingzhao Fang, Bonnie Cantrell and Dongxiao Sun
    Citation: BMC Genomics 2018 19:972
  16. The insect gustatory system plays a central role in the regulation of multiple physiological behaviors and the co-evolution between insects and their hosts. The gustatory receptors (Gr) are important to allow ...

    Authors: Kui Kang, Pan Yang, Li-E Chen, Rui Pang, Lu-Jun Yu, Wen-Wu Zhou, Zeng-Rong Zhu and Wen-Qing Zhang
    Citation: BMC Genomics 2018 19:970
  17. Crohn’s disease is associated with gut dysbiosis. Independent studies have shown an increase in the abundance of certain bacterial species, particularly Escherichia coli with the adherent-invasive pathotype, in t...

    Authors: Alexander V. Tyakht, Alexander I. Manolov, Alexandra V. Kanygina, Dmitry S. Ischenko, Boris A. Kovarsky, Anna S. Popenko, Alexander V. Pavlenko, Anna V. Elizarova, Daria V. Rakitina, Julia P. Baikova, Valentina G. Ladygina, Elena S. Kostryukova, Irina Y. Karpova, Tatyana A. Semashko, Andrei K. Larin, Tatyana V. Grigoryeva…
    Citation: BMC Genomics 2018 19:968
  18. Heart development is a relatively fragile process in which many transcription factor genes show dose-sensitive characteristics such as haploinsufficiency and lower penetrance. Despite efforts to unravel the ge...

    Authors: Yutaro Hori, Yoko Tanimoto, Satoru Takahashi, Tetsushi Furukawa, Kazuko Koshiba-Takeuchi and Jun K. Takeuchi
    Citation: BMC Genomics 2018 19:967
  19. The genus Burkholderia consists of species that occupy remarkably diverse ecological niches. Its best known members are important pathogens, B. mallei and B. pseudomallei, which cause glanders and melioidosis, re...

    Authors: Olga O. Bochkareva, Elena V. Moroz, Iakov I. Davydov and Mikhail S. Gelfand
    Citation: BMC Genomics 2018 19:965
  20. Studies that aim at explaining phenotypes or disease susceptibility by genetic or epigenetic variants often rely on clustering methods to stratify individuals or samples. While statistical associations may poi...

    Authors: Jiangning Gao, Görel Sundström, Behrooz Torabi Moghadam, Neda Zamani and Manfred G. Grabherr
    Citation: BMC Genomics 2018 19:964
  21. A-to-I RNA editing is a co−/post-transcriptional modification catalyzed by ADAR enzymes, that deaminates Adenosines (A) into Inosines (I). Most of known editing events are located within inverted ALU repeats, ...

    Authors: Edoardo Giacopuzzi, Massimo Gennarelli, Chiara Sacco, Alice Filippini, Jessica Mingardi, Chiara Magri and Alessandro Barbon
    Citation: BMC Genomics 2018 19:963
  22. Somatic embryogenesis receptor-like kinases (SERKs) are leucine-rich repeat receptor-like kinases associated with various signaling pathways. These kinases have a relationship with stress signals, and they are...

    Authors: Liwei Zheng, Juanjuan Ma, Jiangping Mao, Sheng Fan, Dong Zhang, Caiping Zhao, Na An and Mingyu Han
    Citation: BMC Genomics 2018 19:962
  23. Cosmoscartini (Hemiptera: Cercopoidea: Cercopidae) is a large and brightly colored Old World tropical tribe, currently containing over 310 phytophagous species (including some economically important pests of e...

    Authors: Tianjuan Su, Bo He, Kui Li and Aiping Liang
    Citation: BMC Genomics 2018 19:961
  24. New single-cell isolation technologies are facilitating studies on the transcriptomics of individual cells. Bio-Rad ddSEQ is a droplet-based microfluidic system that, when coupled with downstream Illumina libr...

    Authors: Dario Romagnoli, Giulia Boccalini, Martina Bonechi, Chiara Biagioni, Paola Fassan, Roberto Bertorelli, Veronica De Sanctis, Angelo Di Leo, Ilenia Migliaccio, Luca Malorni and Matteo Benelli
    Citation: BMC Genomics 2018 19:960
  25. Both human and mouse fibroblasts can be reprogrammed to pluripotency with Oct4, Sox2, Klf4, and c-Myc (OSKM) transcription factors. While both systems generate pluripotency, human reprogramming takes considera...

    Authors: Kai Fu, Constantinos Chronis, Abdenour Soufi, Giancarlo Bonora, Miguel Edwards, Stephen T. Smale, Kenneth S. Zaret, Kathrin Plath and Matteo Pellegrini
    Citation: BMC Genomics 2018 19:956
  26. Flavonoids are important components that confer upon tea plants a unique flavour and health functions. However, the traditional breeding method for selecting a cultivar with a high or unique flavonoid content ...

    Authors: Li-Yi Xu, Li-Yuan Wang, Kang Wei, Li-Qiang Tan, Jing-Jing Su and Hao Cheng
    Citation: BMC Genomics 2018 19:955
  27. The human chromosome 14 microRNA cluster (C14MC) is a conserved microRNA (miRNA) cluster across eutherian mammals, reported to play an important role in placental development. However, the expression kinetics ...

    Authors: Pouya Dini, Peter Daels, Shavahn C. Loux, Alejandro Esteller-Vico, Mariano Carossino, Kirsten E. Scoggin and Barry A. Ball
    Citation: BMC Genomics 2018 19:954
  28. When genomics researchers design a high-throughput study to test for differential expression, some biological systems and research questions provide opportunities to use paired samples from subjects, and resea...

    Authors: John R. Stevens, Jennifer S. Herrick, Roger K. Wolff and Martha L. Slattery
    Citation: BMC Genomics 2018 19:953
  29. Walking catfish (Clarias batrachus) is a freshwater fish capable of air-breathing and locomotion on land. It usually inhabits various low-oxygen habitats, burrows inside the mudflat, and sometimes “walks” to sear...

    Authors: Ning Li, Lisui Bao, Tao Zhou, Zihao Yuan, Shikai Liu, Rex Dunham, Yuanning Li, Kun Wang, Xiaoyan Xu, Yulin Jin, Qifan Zeng, Sen Gao, Qiang Fu, Yang Liu, Yujia Yang, Qi Li…
    Citation: BMC Genomics 2018 19:952
  30. Guar [Cyamopsis tetragonoloba, L. Taub.] is an important industrial crop because of the commercial applications of the galactomannan gum contained in its seeds. Plant breeding programmes based on marker-assisted ...

    Authors: Omika Thakur and Gursharn Singh Randhawa
    Citation: BMC Genomics 2018 19:951
  31. Betula platyphylla is a common tree species in northern China that has high economic and medicinal value. Our laboratory has been devoted to genome research on B. platyphylla for approximately 10 years. As primar...

    Authors: Sui Wang, Chuanping Yang, Xiyang Zhao, Su Chen and Guan-Zheng Qu
    Citation: BMC Genomics 2018 19:950
  32. Bovine papillomavirus (BPV) belongs to the Papillomaviridae family and infects epithelial cells of bovines and closely related animals, causing hyperproliferative lesions known as warts or papillomas, which ma...

    Authors: Débora M. Barreto, Gerlane S. Barros, Lucas A. B. O. Santos, Rosilene C. Soares and Marcus V. A. Batista
    Citation: BMC Genomics 2018 19:949
  33. Genome-scale metabolic modeling is a cornerstone of systems biology analysis of microbial organisms and communities, yet these genome-scale modeling efforts are invariably based on incomplete functional annota...

    Authors: Marc Griesemer, Jeffrey A. Kimbrel, Carol E. Zhou, Ali Navid and Patrik D’haeseleer
    Citation: BMC Genomics 2018 19:948
  34. Genomic selection (GS) can increase genetic gain by reducing the length of breeding cycle in forest trees. Here we genotyped 1370 control-pollinated progeny trees from 128 full-sib families in Norway spruce (Pice...

    Authors: Zhi-Qiang Chen, John Baison, Jin Pan, Bo Karlsson, Bengt Andersson, Johan Westin, María Rosario García-Gil and Harry X. Wu
    Citation: BMC Genomics 2018 19:946
  35. Dissecting the genetic basis of phenotypic diversity is one of the fundamental goals in evolutionary biology. Despite growing evidence for gene expression divergence being responsible for the evolution of comp...

    Authors: Sri Pratima Nandamuri, Matthew A. Conte and Karen L. Carleton
    Citation: BMC Genomics 2018 19:945
  36. Recent advances in sequencing technology have allowed us to investigate personal genomes to find structural variations, which have been studied extensively to identify their association with the physiology of ...

    Authors: Junwoo Bae, Kyeong Won Lee, Mohammad Nazrul Islam, Hyung-Soon Yim, Heejin Park and Mina Rho
    Citation: BMC Genomics 2018 19:944
  37. Root-knot nematodes (RKN), genus Meloidogyne, are plant parasitic worms that have the ability to transform root vascular cylinder cells into hypertrophied, multinucleate and metabolically over-active feeding cell...

    Authors: Clémence Medina, Martine da Rocha, Marc Magliano, Alizée Raptopoulo, Nathalie Marteu, Kevin Lebrigand, Pierre Abad, Bruno Favery and Stéphanie Jaubert-Possamai
    Citation: BMC Genomics 2018 19:943
  38. Norway spruce [Picea abies (L.) Karst.] is ecologically and economically one of the most important conifer worldwide. Our main goal was to develop a large catalog of annotated high confidence gene SNPs that shoul...

    Authors: Aïda Azaiez, Nathalie Pavy, Sébastien Gérardi, Jérôme Laroche, Brian Boyle, France Gagnon, Marie-Josée Mottet, Jean Beaulieu and Jean Bousquet
    Citation: BMC Genomics 2018 19:942
  39. Democratising the growing body of whole genome sequencing data available for Triticum aestivum (bread wheat) has been impeded by the lack of a genome reference and the large computational requirements for analysi...

    Authors: Nathan S. Watson-Haigh, Radosław Suchecki, Elena Kalashyan, Melissa Garcia and Ute Baumann
    Citation: BMC Genomics 2018 19:941
  40. Phosphorus is an important macronutrient that is severely lacking in soils. In plants, specific microRNAs (miRNAs) essential for nutrient management and the regulation of stress responses are responsible for t...

    Authors: Amanda Huen, Julia Bally and Penelope Smith
    Citation: BMC Genomics 2018 19:940
  41. Unlike the chromosome constitution of most snakes (2n=36), the cobra karyotype shows a diploid chromosome number of 38 with a highly heterochromatic W chromosome and a large morphologically different chromosom...

    Authors: Worapong Singchat, Rebecca E. O’Connor, Panupong Tawichasri, Aorarat Suntronpong, Siwapech Sillapaprayoon, Sunutcha Suntrarachun, Narongrit Muangmai, Sudarath Baicharoen, Surin Peyachoknagul, Lawan Chanhome, Darren Griffin and Kornsorn Srikulnath
    Citation: BMC Genomics 2018 19:939
  42. Peanut is the world’s fourth largest oilseed crop that exhibits wide cultivar variations in cadmium (Cd) accumulation. To establish the mechanisms of Cd distribution and accumulation in peanut plants, eight cD...

    Authors: Rugang Yu, Yuanyuan Ma, Yue Li, Xin Li, Caifeng Liu, Xueling Du and Gangrong Shi
    Citation: BMC Genomics 2018 19:938
  43. Nicotiana attenuata is an ecological model plant whose 2.57 Gb genome has recently been sequenced and assembled and for which miRNAs and their genomic locations have been identified. To understand how this plant’...

    Authors: Priyanka Pandey, Ming Wang, Ian T. Baldwin, Shree P. Pandey and Karin Groten
    Citation: BMC Genomics 2018 19:937
  44. Trichophyton rubrum (T. rubrum) is an important model organism of dermatophytes, which are the most common fungal pathogens worldwide. Despite the severity and prevalence of the infection caused by these pathogen...

    Authors: Lingling Wang, Xingye Xu, Jian Yang, Lihong Chen, Bo Liu, Tao Liu and Qi Jin
    Citation: BMC Genomics 2018 19:933
  45. Faecalibacterium prausnitzii is a ubiquitous member of the human gut microbiome, constituting up to 15% of the total bacteria in the human gut. Substantial evidence connects decreased levels of F. prausnitzii wit...

    Authors: Cormac Brian Fitzgerald, Andrey N. Shkoporov, Thomas D. S. Sutton, Andrei V. Chaplin, Vimalkumar Velayudhan, R. Paul Ross and Colin Hill
    Citation: BMC Genomics 2018 19:931

    The Correspondence to this article has been published in BMC Genomics 2020 21:335

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