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  1. Kiwi represent the most basal extant avian lineage (paleognaths) and exhibit biological attributes that are unusual or extreme among living birds, such as large egg size, strong olfaction, nocturnality, flight...

    Authors: Kristina M. Ramstad, Hilary C. Miller and Gabriel Kolle
    Citation: BMC Genomics 2016 17:410
    Content type: Research article Published on:

  2. Haplotypes with reduced or missing homozygosity may harbor deleterious alleles that compromise juvenile survival. A scan for homozygous haplotype deficiency revealed a short segment on bovine chromosome 19 (Br...

    Authors: Hermann Schwarzenbacher, Johann Burgstaller, Franz R. Seefried, Christine Wurmser, Monika Hilbe, Simone Jung, Christian Fuerst, Nora Dinhopl, Herbert Weissenböck, Birgit Fuerst-Waltl, Marlies Dolezal, Reinhard Winkler, Oskar Grueter, Ulrich Bleul, Thomas Wittek, Ruedi Fries…
    Citation: BMC Genomics 2016 17:400
    Content type: Research article Published on:

  3. Whole exome sequencing (WES) has been proven to serve as a valuable basis for various applications such as variant calling and copy number variation (CNV) analyses. For those analyses the read coverage should ...

    Authors: Claudia Pommerenke, Robert Geffers, Boyke Bunk, Sabin Bhuju, Sonja Eberth, Hans G. Drexler and Hilmar Quentmeier
    Citation: BMC Genomics 2016 17:399
    Content type: Methodology Article Published on:

  4. Chrysanthemum morifolium is one of the most important global cut flower and pot plants, and has been cultivated worldwide. However, limited genomic resources are available and the mole...

    Authors: Hua Liu, Ming Sun, Dongliang Du, Huitang Pan, Tangren Cheng, Jia Wang, Qixiang Zhang and Yike Gao
    Citation: BMC Genomics 2016 17:398
    Content type: Research article Published on:

  5. RNA-seq based on short reads generated by next generation sequencing technologies has become the main approach to study differential gene expression. Until now, the main applications of this technique have bee...

    Authors: Montserrat Torres-Oliva, Isabel Almudi, Alistair P. McGregor and Nico Posnien
    Citation: BMC Genomics 2016 17:392
    Content type: Methodology article Published on:

  6. Clostridium perfringens causes toxin-mediated diseases, including gas gangrene (clostridial myonecrosis) and food poisoning in humans. The production of the toxins implicated in gas ga...

    Authors: Lee-Yean Low, Paul F. Harrison, Ya-Hsun Lin, John D. Boyce, Julian I. Rood and Jackie K. Cheung
    Citation: BMC Genomics 2016 17:391
    Content type: Research article Published on:

  7. The Janus kinase (Jak) and signaling transducer activator of transcription (Stat) pathway mediates the signaling of genes required for cellular development and homeostasis. To elucidate the effect of type I IF...

    Authors: Cheng Xu, Øystein Evensen and Hetron Mweemba Munang’andu
    Citation: BMC Genomics 2016 17:390
    Content type: Research article Published on:

  8. The appropriate timing of bolting and flowering is pivotal for reproductive success in Brassicaceae crops including radish (Raphanus sativus L.). Although several flowering regulatory pathways had been described ...

    Authors: Shanshan Nie, Chao Li, Liang Xu, Yan Wang, Danqiong Huang, Everlyne M. Muleke, Xiaochuan Sun, Yang Xie and Liwang Liu
    Citation: BMC Genomics 2016 17:389
    Content type: Research article Published on:

  9. The modelling of gene regulation is a major challenge in biomedical research. This process is dominated by transcription factors (TFs) and mutations in their binding sites (TFBSs) may cause the misregulation o...

    Authors: Daniela Hombach, Jana Marie Schwarz, Peter N. Robinson, Markus Schuelke and Dominik Seelow
    Citation: BMC Genomics 2016 17:388
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2016 17:502

  10. Fusarium graminearum causes Fusarium head blight (FHB), a major disease problem worldwide. Resistance to FHB is controlled by quantitative trait loci (QTL) of which two are located on ...

    Authors: Yadong Huang, Lin Li, Kevin P. Smith and Gary J. Muehlbauer
    Citation: BMC Genomics 2016 17:387
    Content type: Research article Published on:

  11. Hulless barley, also called naked barley, is an important cereal crop worldwide, serving as a healthy food both for human consumption and animal feed. Nevertheless, it often suffered from drought stress during...

    Authors: Xingquan Zeng, Lijun Bai, Zexiu Wei, Hongjun Yuan, Yulin Wang, Qijun Xu, Yawei Tang and Tashi Nyima
    Citation: BMC Genomics 2016 17:386
    Content type: Research article Published on:

  12. Aneuploidy can result in significant phenotypic changes, which can sometimes be selectively advantageous. For example, aneuploidy confers resistance to antifungal drugs in human pathogenic fungi. Aneuploidy ha...

    Authors: Takao Kasuga, Mai Bui, Elizabeth Bernhardt, Tedmund Swiecki, Kamyar Aram, Liliana M. Cano, Joan Webber, Clive Brasier, Caroline Press, Niklaus J. Grünwald, David M. Rizzo and Matteo Garbelotto
    Citation: BMC Genomics 2016 17:385
    Content type: Research article Published on:

  13. Next-generation sequencing now allows for total RNA extracts to be sequenced in non-model organisms such as bamboos, an economically and ecologically important group of grasses. Bamboos are divided into three ...

    Authors: William P. Wysocki, Eduardo Ruiz-Sanchez, Yanbin Yin and Melvin R. Duvall
    Citation: BMC Genomics 2016 17:384
    Content type: Research article Published on:

  14. Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant pigs can result in congenital infection and ultimately fetal death. Little is known about immune responses to infection at the ...

    Authors: Jamie M. Wilkinson, Hua Bao, Andrea Ladinig, Linjun Hong, Paul Stothard, Joan K. Lunney, Graham S. Plastow and John C. S. Harding
    Citation: BMC Genomics 2016 17:383
    Content type: Research article Published on:

  15. Pseudostellaria heterophylla produces both closed (cleistogamous, CL) and open (chasmogamous, CH) flowers on the same individual but in different seasons. The production of CH and CL f...

    Authors: Yan Luo, Jin-Yong Hu, Lu Li, Yin-Ling Luo, Peng-Fei Wang and Bao-Hua Song
    Citation: BMC Genomics 2016 17:382
    Content type: Research article Published on:

  16. Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder that leads to a decline in cognitive function. In AD, aggregates of amyloid β peptide precede the accumulation of neurofibrillary ...

    Authors: Liqi Shu, Wenjia Sun, Liping Li, Zihui Xu, Li Lin, Pei Xie, Hui Shen, Luoxiu Huang, Qi Xu, Peng Jin and Xuekun Li
    Citation: BMC Genomics 2016 17:381
    Content type: Research article Published on:

  17. Understanding how plants and pathogens modulate gene expression during the host-pathogen interaction is key to uncovering the molecular mechanisms that regulate disease progression. Recent advances in sequenci...

    Authors: Albor Dobon, Daniel C. E. Bunting, Luis Enrique Cabrera-Quio, Cristobal Uauy and Diane G. O. Saunders
    Citation: BMC Genomics 2016 17:380
    Content type: Research article Published on:

  18. Copy number variation (CNV) represents an important source of genetic divergence that can produce drastic phenotypic differences and may therefore be subject to selection during domestication and environmental...

    Authors: Xiao Zhang, Kun Wang, Lizhong Wang, Yongzhi Yang, Zhengqiang Ni, Xiuyue Xie, Xuemin Shao, Jin Han, Dongshi Wan and Qiang Qiu
    Citation: BMC Genomics 2016 17:379
    Content type: Research article Published on:

  19. Consuming watercress is thought to provide health benefits as a consequence of its phytonutrient composition. However, for watercress there are currently limited genetic resources underpinning breeding efforts...

    Authors: Nikol Voutsina, Adrienne C. Payne, Robert D. Hancock, Graham J. J. Clarkson, Steve D. Rothwell, Mark A. Chapman and Gail Taylor
    Citation: BMC Genomics 2016 17:378
    Content type: Research article Published on:

  21. The P1B-ATPase subfamily is an important group involved in transporting heavy metals and has been extensively studied in model plants, such as Arabidopsis thaliana and Oryza sativa. Emerging evidence indicates th...

    Authors: Xiaolong Fang, Lei Wang, Xiaojuan Deng, Peng Wang, Qibin Ma, Hai Nian, Yingxiang Wang and Cunyi Yang
    Citation: BMC Genomics 2016 17:376
    Content type: Research article Published on:

  22. Leishmania infantum is the protozoan parasite responsible for zoonotic visceral leishmaniasis in the Mediterranean basin. A recent outbreak in humans has been reported in this area. Th...

    Authors: Pedro J. Alcolea, Ana Alonso, María A. Degayón, Mercedes Moreno-Paz, Maribel Jiménez, Ricardo Molina and Vicente Larraga
    Citation: BMC Genomics 2016 17:375
    Content type: Research article Published on:

  23. The characterization of the ABO blood group status is vital for blood transfusion and solid organ transplantation. Several methods for the molecular characterization of the ABO gene, which encodes the alleles tha...

    Authors: Kathrin Lang, Ines Wagner, Bianca Schöne, Gerhard Schöfl, Kerstin Birkner, Jan A. Hofmann, Jürgen Sauter, Julia Pingel, Irina Böhme, Alexander H. Schmidt and Vinzenz Lange
    Citation: BMC Genomics 2016 17:374
    Content type: Research article Published on:

  24. Soybean is a major source of oil and protein in the human diet and in animal feed. However, as soybean is deficient in sulfur-containing amino acids, its nutritional value is limited. Increasing sulfate assimi...

    Authors: Yiqiong Ding, Xiaoqiong Zhou, Li Zuo, Hui Wang and Deyue Yu
    Citation: BMC Genomics 2016 17:373
    Content type: Research article Published on:

  26. Bones have been subjected to considerable selective pressure throughout vertebrate evolution, such as occurred during the adaptations associated with the development of powered flight. Powered flight evolved i...

    Authors: João Paulo Machado, Warren E. Johnson, M. Thomas P. Gilbert, Guojie Zhang, Erich D. Jarvis, Stephen J. O’Brien and Agostinho Antunes
    Citation: BMC Genomics 2016 17:371
    Content type: Research article Published on:

  27. Magnaporthe oryzae (anamorph Pyricularia oryzae) is the causal agent of blast disease of Poaceae crops and their wild relatives. To understand the genetic mechanisms that drive host sp...

    Authors: Kentaro Yoshida, Diane G. O. Saunders, Chikako Mitsuoka, Satoshi Natsume, Shunichi Kosugi, Hiromasa Saitoh, Yoshihiro Inoue, Izumi Chuma, Yukio Tosa, Liliana M. Cano, Sophien Kamoun and Ryohei Terauchi
    Citation: BMC Genomics 2016 17:370
    Content type: Research article Published on:

  28. Fishes show seasonal patterns of immunity, but such phenomena are imperfectly understood in vertebrates generally, even in humans and mice. As these seasonal patterns may link to infectious disease risk and in...

    Authors: Martha Brown, Pascal Hablützel, Ida M. Friberg, Anna G. Thomason, Alexander Stewart, Justin A. Pachebat and Joseph A. Jackson
    Citation: BMC Genomics 2016 17:369
    Content type: Research article Published on:

  29. With more than 30,000 species, ray-finned fish represent approximately half of vertebrates. The evolution of ray-finned fish was impacted by several whole genome duplication (WGD) events including a teleost-sp...

    Authors: Jeremy Pasquier, Cédric Cabau, Thaovi Nguyen, Elodie Jouanno, Dany Severac, Ingo Braasch, Laurent Journot, Pierre Pontarotti, Christophe Klopp, John H. Postlethwait, Yann Guiguen and Julien Bobe
    Citation: BMC Genomics 2016 17:368
    Content type: Database Published on:

  32. MHC class I genotyping is essential for a wide range of biomedical, immunological and biodiversity applications. Whereas in human a comprehensive MHC class I allele catalogue is available, respective data in n...

    Authors: Wiebke Demasius, Rosemarie Weikard, Frieder Hadlich, Johannes Buitkamp and Christa Kühn
    Citation: BMC Genomics 2016 17:365
    Content type: Research article Published on:

  33. Mammalian genomes encode for thousands of microRNAs, which can potentially regulate the majority of protein-coding genes. They have been implicated in development and disease, leading to great interest in unde...

    Authors: Cesaré Ovando-Vázquez, Daniel Lepe-Soltero and Cei Abreu-Goodger
    Citation: BMC Genomics 2016 17:364
    Content type: Methodology article Published on:

  34. The pathogenesis-related (PR) group of proteins are operationally defined as polypeptides that increase in concentration in plant tissues upon contact with a pathogen. To date, 17 classes of highly divergent p...

    Authors: Andrew S. Fister, Luis C. Mejia, Yufan Zhang, Edward Allen Herre, Siela N. Maximova and Mark J. Guiltinan
    Citation: BMC Genomics 2016 17:363
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Genomics 2016 17:715

  35. The NMDA receptor antagonist ketamine was found to act as a fast-acting antidepressant. The effects of single treatment were reported to persist for days to weeks, even in otherwise treatment-refractory cases....

    Authors: Joanna Ficek, Magdalena Zygmunt, Marcin Piechota, Dzesika Hoinkis, Jan Rodriguez Parkitna, Ryszard Przewlocki and Michal Korostynski
    Citation: BMC Genomics 2016 17:362
    Content type: Research article Published on:

  36. Rare cell subtypes can profoundly impact the course of human health and disease, yet their presence within a sample is often missed with bulk molecular analysis. Single-cell analysis tools such as FACS, FISH-F...

    Authors: Maurizio Pellegrino, Adam Sciambi, Jamie L. Yates, Joshua D. Mast, Charles Silver and Dennis J. Eastburn
    Citation: BMC Genomics 2016 17:361
    Content type: Methodology article Published on:

  37. The length of cotton fiber is an important agronomic trait that directly affects the quality of yarn and fabric. Understanding the molecular basis of fiber elongation would provide a means for improvement of f...

    Authors: Marina Naoumkina, Gregory N. Thyssen, David D. Fang, Doug J. Hinchliffe, Christopher B. Florane and Johnie N. Jenkins
    Citation: BMC Genomics 2016 17:360
    Content type: Research article Published on:

  38. Self-incompatibility (SI) is under genetic control and prevents inbreeding depression in angiosperms. SI mechanisms are quite complicated and still poorly understood in many plants. Tea (Camellia sinensis L.) bel...

    Authors: Cheng-Cai Zhang, Li-Yuan Wang, Kang Wei, Li-Yun Wu, Hai-Lin Li, Fen Zhang, Hao Cheng and De-Jiang Ni
    Citation: BMC Genomics 2016 17:359
    Content type: Research article Published on:

  39. Fungal conidia are usually dormant unless the extracellular conditions are right for germination. Despite the importance of dormancy, little is known about the molecular mechanism underlying entry to, maintena...

    Authors: Daisuke Hagiwara, Hiroki Takahashi, Yoko Kusuya, Susumu Kawamoto, Katsuhiko Kamei and Tohru Gonoi
    Citation: BMC Genomics 2016 17:358
    Content type: Research article Published on:

  40. A growing number of studies report an abnormal expression of Piwi-interacting RNAs (piRNAs) and the piRNA processing enzyme Piwi in many cancers. Whether this finding is an epiphenomenon of the chaotic molecul...

    Authors: Susanne Kneitz, Rasmi R. Mishra, Domitille Chalopin, John Postlethwait, Wesley C. Warren, Ronald B. Walter and Manfred Schartl
    Citation: BMC Genomics 2016 17:357
    Content type: Research article Published on:

  41. CRISPR (clustered regularly interspaced short palindromic repeats) RNAs provide the specificity for noncoding RNA-guided adaptive immune defence systems in prokaryotes. CRISPR arrays consist of repeat sequence...

    Authors: Ambarish Biswas, Raymond H.J. Staals, Sergio E. Morales, Peter C. Fineran and Chris M. Brown
    Citation: BMC Genomics 2016 17:356
    Content type: Software Published on:

  42. Proximity ligation-mediated methods are essential to study the impact of three-dimensional chromatin organization on gene programming. Albeit significant progress has been made in the development of computatio...

    Authors: Marco-Antonio Mendoza-Parra, Matthias Blum, Valeriya Malysheva, Pierre-Etienne Cholley and Hinrich Gronemeyer
    Citation: BMC Genomics 2016 17:355
    Content type: Database Published on:

  43. Sporisorium scitamineum causes the sugarcane smut disease, one of the most serious constraints to global sugarcane production. S. scitamineum possesses a sexual mating system composed ...

    Authors: Meixin Yan, Weijun Dai, Enping Cai, Yi Zhen Deng, Changqing Chang, Zide Jiang and Lian-Hui Zhang
    Citation: BMC Genomics 2016 17:354
    Content type: Research article Published on:

  44. The respiratory tract of swine is colonized by several bacteria among which are three Mycoplasma species: Mycoplasma flocculare, Mycoplasma hyopneumoniae and Mycoplasma hyorhinis. While colonization by M. floccul...

    Authors: Mariana G. Ferrarini, Franciele M. Siqueira, Scheila G. Mucha, Tony L. Palama, Élodie Jobard, Bénédicte Elena-Herrmann, Ana T. R. Vasconcelos, Florence Tardy, Irene S. Schrank, Arnaldo Zaha and Marie-France Sagot
    Citation: BMC Genomics 2016 17:353
    Content type: Research Article Published on:

  45. Since upland cotton was introduced into China during the 1920s–1950s, hundreds of inbreed cultivars have been developed. To explore the molecular diversity, population structure and elite alleles, 503 inbred c...

    Authors: Xinhui Nie, Cong Huang, Chunyuan You, Wu Li, Wenxia Zhao, Chao Shen, Beibei Zhang, Hantao Wang, Zhenhua Yan, Baoshen Dai, Maojun Wang, Xianlong Zhang and Zhongxu Lin
    Citation: BMC Genomics 2016 17:352
    Content type: Research article Published on:

  46. P. aeruginosa is one of the top three causes of opportunistic human bacterial infections. The remarkable variability in the clinical outcomes of this infection is thought to be associa...

    Authors: Maura De Simone, Lorenza Spagnuolo, Nicola Ivan Lorè, Cristina Cigana, Ida De Fino, Karl W. Broman, Fuad A. Iraqi and Alessandra Bragonzi
    Citation: BMC Genomics 2016 17:351
    Content type: Research article Published on:

  47. Nitrogen (N) is an essential and often limiting nutrient to plant growth and development. Previous studies have shown that the mRNA expressions of numerous genes are regulated by nitrogen supplies; however, li...

    Authors: Yuanda Lv, Zhikai Liang, Min Ge, Weicong Qi, Tifu Zhang, Feng Lin, Zhaohua Peng and Han Zhao
    Citation: BMC Genomics 2016 17:350
    Content type: Research article Published on:

  48. Huanglongbing (HLB) and tristeza, are diseases of citrus caused by a member of the α-proteobacteria, ‘Candidatus Liberibacter asiaticus’ (CaLas), and Citrus tristeza virus (CTV) respectively. HLB is a devastating...

    Authors: Shimin Fu, Jonathan Shao, Changyong Zhou and John S. Hartung
    Citation: BMC Genomics 2016 17:349
    Content type: Research article Published on:

  50. Plant-pathogen interactions at early stages of infection are important to the fate of interaction. Xanthomonas oryzae pv. oryzae (Xoo) causes bacterial blight, which is a devastating disease in rice. Although in ...

    Authors: Seunghwan Kim, Yong-Joon Cho, Eun-Sung Song, Sang Hee Lee, Jeong-Gu Kim and Lin-Woo Kang
    Citation: BMC Genomics 2016 17:345
    Content type: Research article Published on:

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BMC Genomics

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