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  1. Cilia are critical for diverse functions, from motility to signal transduction, and ciliary dysfunction causes inherited diseases termed ciliopathies. Several ciliopathy proteins influence developmental signal...

    Authors: Amy R Barker, Karen S Renzaglia, Kimberley Fry and Helen R Dawe
    Citation: BMC Genomics 2014 15:531
    Content type: Research article Published on:

  2. By reshuffling genomes, structural genomic reorganizations provide genetic variation on which natural selection can work. Understanding the mechanisms underlying this process has been a long-standing question ...

    Authors: Anna Ullastres, Marta Farré, Laia Capilla and Aurora Ruiz-Herrera
    Citation: BMC Genomics 2014 15:530
    Content type: Research article Published on:

  3. The ST239 lineage is a globally disseminated, multiply drug-resistant hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA). We performed whole-genome sequencing of representative HA-MRSA isol...

    Authors: Zheng Wang, Haokui Zhou, Hui Wang, Hongbin Chen, K K Leung, Stephen Tsui and Margaret Ip
    Citation: BMC Genomics 2014 15:529
    Content type: Research article Published on:

  5. In light of the changes in precipitation and soil water availability expected with climate change, understanding the mechanisms underlying plant responses to water deficit is essential. Toward that end we have...

    Authors: Eli Meyer, Michael J Aspinwall, David B Lowry, Juan Diego Palacio-Mejía, Tierney L Logan, Philip A Fay and Thomas E Juenger
    Citation: BMC Genomics 2014 15:527
    Content type: Research article Published on:

  6. Genomes of higher eukaryotes have surprisingly long first introns and in some cases, the first introns have been shown to have higher conservation relative to other introns. However, the functional relevance o...

    Authors: Seung Gu Park, Sridhar Hannenhalli and Sun Shim Choi
    Citation: BMC Genomics 2014 15:526
    Content type: Research article Published on:

  7. Several miRNAs are known to control myogenesis in vertebrates. Some of them are specifically expressed in muscle while others have a broader tissue expression but are still involved in establishing the muscle ...

    Authors: Catarina Campos, Arvind YM Sundaram, Luisa MP Valente, Luis EC Conceição, Sofia Engrola and Jorge MO Fernandes
    Citation: BMC Genomics 2014 15:525
    Content type: Research article Published on:

  8. The change from juvenile to mature phase in woody plants is often accompanied by a gradual loss of rooting ability, as well as by reduced microRNA (miR) 156 and increased miR172 expression.

    Authors: Aviv Levy, David Szwerdszarf, Mohamad Abu-Abied, Inna Mordehaev, Yossi Yaniv, Joseph Riov, Tzahi Arazi and Einat Sadot
    Citation: BMC Genomics 2014 15:524
    Content type: Research article Published on:

  9. Proteases can hydrolyze peptides in aqueous environments. This property has made proteases the most important industrial enzymes by taking up about 60% of the total enzyme market. Microorganisms are the main s...

    Authors: Sebnem Ozturkoglu Budak, Miaomiao Zhou, Carlo Brouwer, Ad Wiebenga, Isabelle Benoit, Marcos Di Falco, Adrian Tsang and Ronald P de Vries
    Citation: BMC Genomics 2014 15:523
    Content type: Research article Published on:

  10. The Aquificales are a diverse group of thermophilic bacteria that thrive in terrestrial and marine hydrothermal environments. They can be divided into the families Aquificaceae, Desulfurobacteriaceae and Hydrogen...

    Authors: Marcus Lechner, Astrid I Nickel, Stefanie Wehner, Konstantin Riege, Nicolas Wieseke, Benedikt M Beckmann, Roland K Hartmann and Manja Marz
    Citation: BMC Genomics 2014 15:522
    Content type: Research article Published on:

  11. Recent studies have demonstrated that antisense transcription is pervasive in budding yeasts and is conserved between Saccharomyces cerevisiae and S. paradoxus. While studies have examined antisense transcripts o...

    Authors: Krishna B S Swamy, Chih-Hsu Lin, Ming-Ren Yen, Chuen-Yi Wang and Daryi Wang
    Citation: BMC Genomics 2014 15:521
    Content type: Research article Published on:

  12. The ZNF217 gene, encoding a C2H2 zinc finger protein, is located at 20q13 and found amplified and overexpressed in greater than 20% of breast tumors. Current studies indicate ZNF217 drives tumorigenesis, yet the ...

    Authors: Seth Frietze, Henriette O’Geen, Laurie E Littlepage, Catalina Simion, Colleen A Sweeney, Peggy J Farnham and Sheryl R Krig
    Citation: BMC Genomics 2014 15:520
    Content type: Research article Published on:

  14. Multiple tick saliva proteins, the majority of which are unknown, confer tick resistance in repeatedly infested animals. The objective of this study was to identify the 24-48 h fed Amblyomma americanum tick saliv...

    Authors: Željko M Radulović, Tae K Kim, Lindsay M Porter, Sing-Hoi Sze, Lauren Lewis and Albert Mulenga
    Citation: BMC Genomics 2014 15:518
    Content type: Research article Published on:

  15. The chicken (Gallus gallus) is an important model organism that bridges the evolutionary gap between mammals and other vertebrates. Copy number variations (CNVs) are a form of genomic structural variation widely ...

    Authors: Hui Zhang, Zhi-Qiang Du, Jia-Qiang Dong, Hai-Xia Wang, Hong-Yan Shi, Ning Wang, Shou-Zhi Wang and Hui Li
    Citation: BMC Genomics 2014 15:517
    Content type: Research article Published on:

  16. The Ion Torrent PGM is a popular benchtop sequencer that shows promise in replacing conventional Sanger sequencing as the gold standard for mutation detection. Despite the PGM’s reported high accuracy in calli...

    Authors: Zhen Xuan Yeo, Joshua Chee Leong Wong, Steven G Rozen and Ann Siew Gek Lee
    Citation: BMC Genomics 2014 15:516
    Content type: Methodology article Published on:

  17. Large amounts of microarray expression data have been generated for the Apicomplexan parasite Toxoplasma gondii in an effort to identify genes critical for virulence or developmental transitions. However, researc...

    Authors: Matthew McKnight Croken, Weigang Qiu, Michael W White and Kami Kim
    Citation: BMC Genomics 2014 15:515
    Content type: Methodology article Published on:

  18. The carnitine acetyltransferase (CrAT) is a mitochondrial matrix protein that directly influences intramitochondrial acetyl-CoA pools. Murine CrAT is encoded by a single gene located in the opposite orientatio...

    Authors: Klemens Kienesberger, Aniko Ginta Pordes, Thomas Georg Völk and Reinhold Hofbauer
    Citation: BMC Genomics 2014 15:514
    Content type: Research article Published on:

  19. Understanding mechanisms that contribute to viral dissemination in mosquito vectors will contribute to our ability to interfere with the transmission of viral pathogens that impact public health. The expressio...

    Authors: Dongyoung Shin, Ayse Civana, Carolina Acevedo and Chelsea T Smartt
    Citation: BMC Genomics 2014 15:513
    Content type: Research article Published on:

  21. Obesity is a multifactor disease associated with cardiovascular disorders such as hypertension. Recently, gut microbiota was linked to obesity pathogenesisand shown to influence the host metabolism. Moreover, ...

    Authors: Bernardo A Petriz, Alinne P Castro, Jeeser A Almeida, Clarissa PC Gomes, Gabriel R Fernandes, Ricardo H Kruger, Rinaldo W Pereira and Octavio L Franco
    Citation: BMC Genomics 2014 15:511
    Content type: Research article Published on:

  22. Soybean is one of the most economically important crops in the world. The cotyledon is the nutrient storage area in seeds, and it is critical for seed quality and yield. Cotyledon mutants are important for the...

    Authors: Guixia Shi, Fang Huang, Yu Gong, Guangli Xu, Jingjing Yu, Zhenbin Hu, Qingsheng Cai and Deyue Yu
    Citation: BMC Genomics 2014 15:510
    Content type: Research article Published on:

  23. In recent years advances have been made in the investigative methods of molecular background of canine heart disease. Studies have been conducted to identify specific genes which, when pathologically expressed...

    Authors: Magdalena Hulanicka, Magdalena Garncarz, Marta Parzeniecka-Jaworska and Michał Jank
    Citation: BMC Genomics 2014 15:509
    Content type: Research article Published on:

  24. A wealth of genome sequences has provided thousands of genes of unknown function, but identification of functions for the large numbers of hypothetical genes in phytopathogens remains a challenge that impacts ...

    Authors: Bing Ma, Amy O Charkowski, Jeremy D Glasner and Nicole T Perna
    Citation: BMC Genomics 2014 15:508
    Content type: Research article Published on:

  25. The brown planthopper (Nilaparvata lugens) is one of the most destructive rice plant pests in Asia. N. lugens causes extensive damage to rice by sucking rice phloem sap, which results in hopper burn (complete dea...

    Authors: Yan-Yuan Bao, Xia Qin, Bing Yu, Li-Bo Chen, Zhe-Chao Wang and Chuan-Xi Zhang
    Citation: BMC Genomics 2014 15:507
    Content type: Research article Published on:

  26. Although captured and cultivated marine shrimp constitute highly important seafood in terms of both economic value and production quantity, biologists have little knowledge of the shrimp genome and this partly...

    Authors: Parpakron Korshkari, Sirintra Vaiwsri, Timothy W Flegel, Sudsanguan Ngamsuriyaroj, Burachai Sonthayanon and Anuphap Prachumwat
    Citation: BMC Genomics 2014 15:506
    Content type: Database Published on:

  27. The burst size of a phage is important prior to phage therapy and probiotic usage. The efficiency for a phage to burst its host bacterium can result from molecular domino effects of the phage gene expressions ...

    Authors: Wangta Liu, Ying-Rong Lin, Ming-Wei Lu, Ping-Jyun Sung, Wei-Hsien Wang and Chan-Shing Lin
    Citation: BMC Genomics 2014 15:505
    Content type: Research article Published on:

  30. To combat infection to biotic stress plants elicit the biosynthesis of numerous natural products, many of which are valuable pharmaceutical compounds. Jasmonate is a central regulator of defense response to pa...

    Authors: Craig Schluttenhofer, Sitakanta Pattanaik, Barunava Patra and Ling Yuan
    Citation: BMC Genomics 2014 15:502
    Content type: Research article Published on:

  31. The chemical senses of insects mediate behaviors that are closely linked to survival and reproduction. The order Diptera contains two model organisms, the vinegar fly Drosophila melanogaster and the mosquito Anop...

    Authors: Martin N Andersson, Elin Videvall, Kimberly KO Walden, Marion O Harris, Hugh M Robertson and Christer Löfstedt
    Citation: BMC Genomics 2014 15:501
    Content type: Research article Published on:

  32. The species Neorhizobium galegae comprises two symbiovars that induce nodules on Galega plants. Strains of both symbiovars, orientalis and officinalis, induce nodules on the same plant species, but fix nitrogen o...

    Authors: Janina Österman, Joanne Marsh, Pia K Laine, Zhen Zeng, Edward Alatalo, John T Sullivan, J Peter W Young, Jane Thomas-Oates, Lars Paulin and Kristina Lindström
    Citation: BMC Genomics 2014 15:500
    Content type: Research article Published on:

  33. The advent of large-scale gene expression technologies has helped to reveal in eukaryotic cells, the existence of thousands of non-coding transcripts, whose function and significance remain mostly poorly under...

    Authors: Coline Billerey, Mekki Boussaha, Diane Esquerré, Emmanuelle Rebours, Anis Djari, Cédric Meersseman, Christophe Klopp, Daniel Gautheret and Dominique Rocha
    Citation: BMC Genomics 2014 15:499
    Content type: Research article Published on:

  34. Several major crop species are current or ancient polyploids. To better describe the genetic factors controlling traits of agronomic interest (QTL), it is necessary to understand the structural and functional ...

    Authors: Berline Fopa Fomeju, Cyril Falentin, Gilles Lassalle, Maria J Manzanares-Dauleux and Régine Delourme
    Citation: BMC Genomics 2014 15:498
    Content type: Research article Published on:

  35. In order to get global molecular understanding of one of the most important crop diseases worldwide, we investigated compatible and incompatible interactions between Phytophthora infestans and potato (Solanum tub...

    Authors: Ashfaq Ali, Erik Alexandersson, Marianne Sandin, Svante Resjö, Marit Lenman, Pete Hedley, Fredrik Levander and Erik Andreasson
    Citation: BMC Genomics 2014 15:497
    Content type: Research article Published on:

  36. The free-living amoeba Naegleria fowleri is the causative agent of the rapidly progressing and typically fatal primary amoebic meningoencephalitis (PAM) in humans. Despite the devastating nature of this disease, ...

    Authors: Denise C Zysset-Burri, Norbert Müller, Christian Beuret, Manfred Heller, Nadia Schürch, Bruno Gottstein and Matthias Wittwer
    Citation: BMC Genomics 2014 15:496
    Content type: Research article Published on:

  37. In conditions of nitrogen limitation, Saccharomyces cerevisiae strains differ in their fermentation capacities, due to differences in their nitrogen requirements. The mechanisms ensuring the maintenance of glycol...

    Authors: Claire Brice, Isabelle Sanchez, Frédéric Bigey, Jean-Luc Legras and Bruno Blondin
    Citation: BMC Genomics 2014 15:495
    Content type: Research article Published on:

  38. Recent chromatin immunoprecipitation (ChIP) experiments in fly, mouse, and human have revealed the existence of high-occupancy target (HOT) regions or “hotspots” that show enrichment across many assayed DNA-bi...

    Authors: Lucas D Ward, Junbai Wang and Harmen J Bussemaker
    Citation: BMC Genomics 2014 15:494
    Content type: Research article Published on:

  40. It is well known that mushrooms produce defense proteins and secondary metabolites against predators and competitors; however, less is known about the correlation between the tissue-specific expression and the...

    Authors: David Fernando Plaza, Chia-Wei Lin, Niels Sebastiaan Johannes van der Velden, Markus Aebi and Markus Künzler
    Citation: BMC Genomics 2014 15:492
    Content type: Research article Published on:

  41. Black pearl farming is based on culture of the blacklip pearl oyster Pinctada margaritifera (Mollusca, lophotrochozoa), a protandrous hermaphrodite species. At first maturation, all individuals are males. The fem...

    Authors: Vaihiti Teaniniuraitemoana, Arnaud Huvet, Peva Levy, Christophe Klopp, Emeline Lhuillier, Nabila Gaertner-Mazouni, Yannick Gueguen and Gilles Le Moullac
    Citation: BMC Genomics 2014 15:491
    Content type: Research article Published on:

  42. Enterococcus mundtii is a yellow-pigmented microorganism rarely found in human infections. The draft genome sequence of E. mundtii was recently announced. Its genome encodes at least 2,589 genes and 57 RNAs, and ...

    Authors: Guillermo D Repizo, Martín Espariz, Víctor S Blancato, Cristian A Suárez, Luis Esteban and Christian Magni
    Citation: BMC Genomics 2014 15:489
    Content type: Research article Published on:

  43. Reprogrammed cells, including induced pluripotent stem cells (iPSCs) and nuclear transfer embryonic stem cells (NT-ESCs), are similar in many respects to natural embryonic stem cells (ESCs). However, previous ...

    Authors: Botao Zhao, Dehua Yang, Jing Jiang, Jinsong Li, Chunsun Fan, Menggui Huang, Yi Fan, Yan Jin and Youxin Jin
    Citation: BMC Genomics 2014 15:488
    Content type: Research article Published on:

  44. Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new av...

    Authors: Geneviève Almouzni, Lucia Altucci, Bruno Amati, Neil Ashley, David Baulcombe, Nathalie Beaujean, Christoph Bock, Erik Bongcam-Rudloff, Jean Bousquet, Sigurd Braun, Brigitte Bressac-de Paillerets, Marion Bussemakers, Laura Clarke, Ana Conesa, Xavier Estivill, Alireza Fazeli…
    Citation: BMC Genomics 2014 15:487
    Content type: Correspondence Published on:

  45. Saprophytic filamentous fungi are ubiquitous micro-organisms that play an essential role in photosynthetic carbon recycling. The wood-decayer Pycnoporus cinnabarinus is a model fungus for the study of plant cell ...

    Authors: Anthony Levasseur, Anne Lomascolo, Olivier Chabrol, Francisco J Ruiz-Dueñas, Eva Boukhris-Uzan, François Piumi, Ursula Kües, Arthur F J Ram, Claude Murat, Mireille Haon, Isabelle Benoit, Yonathan Arfi, Didier Chevret, Elodie Drula, Min Jin Kwon, Philippe Gouret…
    Citation: BMC Genomics 2014 15:486
    Content type: Research article Published on:

  46. MicroRNAs (miRNAs) are small, non-coding RNAs that regulate protein levels post-transcriptionally. miRNAs play important regulatory roles in many cellular processes and have been implicated in several diseases...

    Authors: Rounak Nassirpour, Sachin Mathur, Mark M Gosink, Yizheng Li, Ahmed M Shoieb, Joanna Wood, Shawn P O’Neil, Bruce L Homer and Laurence O Whiteley
    Citation: BMC Genomics 2014 15:485
    Content type: Research article Published on:

  47. The mammalian inner ear contains sensory organs, the organ of Corti in the cochlea and cristae and maculae in the vestibule, with each comprised of patterned sensory epithelia that are responsible for hearing ...

    Authors: Anya Rudnicki, Ofer Isakov, Kathy Ushakov, Shaked Shivatzki, Inbal Weiss, Lilach M Friedman, Noam Shomron and Karen B Avraham
    Citation: BMC Genomics 2014 15:484
    Content type: Research article Published on:

  48. Alteromonas is a genus of marine bacteria that is very easy to isolate and grow in the laboratory. There are genomes available of the species Alteromonas macleodii from different locations around the world and an...

    Authors: Mario López-Pérez, Aitor Gonzaga, Elena P Ivanova and Francisco Rodriguez-Valera
    Citation: BMC Genomics 2014 15:483
    Content type: Research article Published on:

  49. In recent years, the number of human infections caused by opportunistic pathogens has increased dramatically. Plant rhizospheres are one of the most typical natural reservoirs for these pathogens but they also...

    Authors: Peyman Alavi, Margaret R Starcher, Gerhard G Thallinger, Christin Zachow, Henry Müller and Gabriele Berg
    Citation: BMC Genomics 2014 15:482
    Content type: Research article Published on:

  50. Polychlorinated biphenyls (PCBs) are persistent organic pollutants (POPs) with harmful effects in animals and humans. Although PCB 153 is one of the most abundant among PCBs detected in animal tissues, its mec...

    Authors: Fekadu Yadetie, Odd André Karlsen, Marta Eide, Christer Hogstrand and Anders Goksøyr
    Citation: BMC Genomics 2014 15:481
    Content type: Research article Published on:

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BMC Genomics

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