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  1. GGPP (geranylgeranyl diphosphate) is produced in the isoprenoid pathway and mediates the function of various plant metabolites, which is synthesized by GGPPS (GGPP synthases) in plants. GGPPS characterization has...

    Authors: Faiza Ali, Ghulam Qanmber, Zhenzhen Wei, Daoqian Yu, Yong hui Li, Lei Gan, Fuguang Li and Zhi Wang
    Citation: BMC Genomics 2020 21:561
  2. High temperatures, particularly at night, decrease rice yield and quality. As high nighttime temperatures (HNTs) become increasingly frequent due to climate change, it is imperative to develop rice crops that ...

    Authors: Chao He, Hong-Yu Zhang, Yong-Xin Zhang, Pei Fu, Li-Li You, Wen-Bo Xiao, Zhao-Hai Wang, Hai-Yan Song, Ying-Jin Huang and Jiang-Lin Liao
    Citation: BMC Genomics 2020 21:560
  3. Mud crab, Scylla paramamosain, a euryhaline crustacean species, mainly inhabits the Indo-Western Pacific region. Wild mud crab spawn in high-salt condition and the salinity reduced with the growth of the hatching...

    Authors: Yin Zhang, Qingyang Wu, Shaobin Fang, Shengkang Li, Huaiping Zheng, Yueling Zhang, Mhd Ikhwanuddin and Hongyu Ma
    Citation: BMC Genomics 2020 21:559
  4. Rainbow trout is a significant fish farming species under temperate climates. Female reproduction traits play an important role in the economy of breeding companies with the sale of fertilized eggs. The object...

    Authors: J. D’Ambrosio, R. Morvezen, S. Brard-Fudulea, A. Bestin, A. Acin Perez, D. Guéméné, C. Poncet, P. Haffray, M. Dupont-Nivet and F. Phocas
    Citation: BMC Genomics 2020 21:558
  5. Tea plant is one of the most important non-alcoholic beverage crops worldwide. While potassium (K+) is an essential macronutrient and greatly affects the growth and development of plants, the molecular mechanism ...

    Authors: Tianyuan Yang, Xin Lu, Yan Wang, Yunxia Xie, Jingzhen Ma, Xunmin Cheng, Enhua Xia, Xiaochun Wan and Zhaoliang Zhang
    Citation: BMC Genomics 2020 21:556
  6. Statins are widely prescribed to lower plasma low-density lipoprotein cholesterol levels. Though statins reduce cardiovascular disease risk overall, statin efficacy varies, and some people experience adverse s...

    Authors: Elizabeth Theusch, Yii-Der I. Chen, Jerome I. Rotter, Ronald M. Krauss and Marisa W. Medina
    Citation: BMC Genomics 2020 21:555
  7. Advances in next-generation sequencing technologies have provided an opportunity to perform population-level comparative genomic analysis to discover unique genomic characteristics of domesticated animals. Duc...

    Authors: Daehwan Lee, Jongin Lee, Kang-Neung Heo, Kisang Kwon, Youngbeen Moon, Dajeong Lim, Kyung-Tai Lee and Jaebum Kim
    Citation: BMC Genomics 2020 21:554
  8. The reblooming bearded iris (Iris germanica) can bloom twice a year, in spring and autumn. The extended ornamental period makes it more popular and brings additional commercial values. However, little is known ab...

    Authors: Zhuping Fan, Yike Gao, Yi Ren, Chunjing Guan, Rong Liu and Qixiang Zhang
    Citation: BMC Genomics 2020 21:553
  9. Goldfish is an important model for various areas of research, including neural development and behavior and a species of significant importance in aquaculture, especially as an ornamental species. It has a mal...

    Authors: Ming Wen, Romain Feron, Qiaowei Pan, Justine Guguin, Elodie Jouanno, Amaury Herpin, Christophe Klopp, Cedric Cabau, Margot Zahm, Hugues Parrinello, Laurent Journot, Shawn M. Burgess, Yoshihiro Omori, John H. Postlethwait, Manfred Schartl and Yann Guiguen
    Citation: BMC Genomics 2020 21:552
  10. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Satoru Onizuka, Yasuharu Yamazaki, Sung-Joon Park, Takayuki Sugimoto, Yumiko Sone, Sebastian Sjöqvist, Michihiko Usui, Akira Takeda, Kenta Nakai, Keisuke Nakashima and Takanori Iwata
    Citation: BMC Genomics 2020 21:551

    The original article was published in BMC Genomics 2020 21:417

  11. Saline, alkaline, and saline-alkaline stress severely affect plant growth and development. The tolerance of plants to these stressors has long been important breeding objectives, especially for woody perennial...

    Authors: Jing Liu, Fei Shen, Yao Xiao, Hongcheng Fang, Changpeng Qiu, Wei Li, Ting Wu, Xuefeng Xu, Yi Wang, Xinzhong Zhang and Zhenhai Han
    Citation: BMC Genomics 2020 21:550
  12. Coral reefs are among the most diverse, complex and densely populated marine ecosystems. To survive, morphologically simple and sessile cnidarians have developed mechanisms to catch prey, deter predators and c...

    Authors: Oshra Yosef, Yotam Popovits, Assaf Malik, Maya Ofek-Lalzer, Tali Mass and Daniel Sher
    Citation: BMC Genomics 2020 21:548
  13. The Asian tiger mosquito, Aedes albopictus, is a highly dangerous invasive vector of numerous medically important arboviruses including dengue, chikungunya and Zika. In four decades it has spread from tropical So...

    Authors: Ludvik M. Gomulski, Mosè Manni, Davide Carraretto, Tony Nolan, Daniel Lawson, José M. Ribeiro, Anna R. Malacrida and Giuliano Gasperi
    Citation: BMC Genomics 2020 21:547
  14. Many insects can develop differential biotypes on variable host plants, but the underlying molecular factors and mechanisms are not well understood. To address this issue, transcriptome profiling analyses were...

    Authors: Da Wang, Deguang Liu, Xiaoqin Shi, Yujing Yang, Na Zhang and Zheming Shang
    Citation: BMC Genomics 2020 21:546
  15. Genomic selection has been successfully implemented in many livestock and crop species. The genomic best linear unbiased predictor (GBLUP) approach, assigning equal variance to all SNP effects, is one of the r...

    Authors: José Luis Gualdrón Duarte, Ann-Stephan Gori, Xavier Hubin, Daniela Lourenco, Carole Charlier, Ignacy Misztal and Tom Druet
    Citation: BMC Genomics 2020 21:545
  16. Full chloroplast genomes provide high resolution taxonomic discrimination between closely related plant species and are quickly replacing single and multi-locus barcoding regions as reference materials of choi...

    Authors: Jorge Villacrés-Vallejo, José Aranda-Ventura, Anna Wallis, Robin Cagle, Sara M. Handy, Jeffery Davis, Elizabeth Reed, Shu Zhang, Errol Strain, Monica Pava-Ripoll, David Erickson, Padmini Ramachandran and Andrea Ottesen
    Citation: BMC Genomics 2020 21:544
  17. Polar bears are uniquely adapted to an Arctic existence. Since their relatively recent divergence from their closest living relative, brown bears, less than 500,000 years ago, the species has evolved an array ...

    Authors: Jose Alfredo Samaniego Castruita, Michael V. Westbury and Eline D. Lorenzen
    Citation: BMC Genomics 2020 21:543
  18. The development of genome-wide genotyping resources has provided terrestrial livestock and crop industries with the unique ability to accurately assess genomic relationships between individuals, uncover the ge...

    Authors: Jarrod L. Guppy, David B. Jones, Shannon R. Kjeldsen, Agnes Le Port, Mehar S. Khatkar, Nicholas M. Wade, Melony J. Sellars, Eike J. Steinig, Herman W. Raadsma, Dean R. Jerry and Kyall R. Zenger
    Citation: BMC Genomics 2020 21:541
  19. The South African claw-toed frog, Xenopus laevis, is uniquely suited for studying differences between regenerative and non-regenerative responses to CNS injury within the same organism, because some CNS neurons (...

    Authors: Jamie L. Belrose, Aparna Prasad, Morgan A. Sammons, Kurt M. Gibbs and Ben G. Szaro
    Citation: BMC Genomics 2020 21:540
  20. Closely related species of the carp family (Cyprinidae) have evolved distinctive abilities to survive under cold stress, but molecular mechanisms underlying the generation of cold resistance remain largely unknow...

    Authors: Guodong Ge, Yong Long, Lianyu Shi, Jing Ren, Junjun Yan, Chitao Li, Qing Li and Zongbin Cui
    Citation: BMC Genomics 2020 21:539
  21. Greying of the hair is an obvious sign of human aging. In addition to age, sex- and ancestry-specific patterns of hair greying are also observed and the progression of greying may be affected by environmental ...

    Authors: Ewelina Pośpiech, Magdalena Kukla-Bartoszek, Joanna Karłowska-Pik, Piotr Zieliński, Anna Woźniak, Michał Boroń, Michał Dąbrowski, Magdalena Zubańska, Agata Jarosz, Tomasz Grzybowski, Rafał Płoski, Magdalena Spólnicka and Wojciech Branicki
    Citation: BMC Genomics 2020 21:538
  22. Frost is a limiting abiotic stress for the winter pea crop (Pisum sativum L.) and identifying the genetic determinants of frost tolerance is a major issue to breed varieties for cold northern areas. Quantitative ...

    Authors: Sana Beji, Véronique Fontaine, Rosemonde Devaux, Martine Thomas, Sandra Silvia Negro, Nasser Bahrman, Mathieu Siol, Grégoire Aubert, Judith Burstin, Jean-Louis Hilbert, Bruno Delbreil and Isabelle Lejeune-Hénaut
    Citation: BMC Genomics 2020 21:536
  23. Water spinach (Ipomoea aquatica) is an important heat-resistant leafy vegetable that can survive under long-time heat stress condition. However, the physiological characteristics and molecular changes in its resp...

    Authors: Rongfang Guo, Xingru Wang, Xiaoyun Han, Xiaodong Chen and Gefu Wang-Pruski
    Citation: BMC Genomics 2020 21:533
  24. Alternanthera philoxeroides (alligator weed) is a highly invasive alien plant that has continuously and successfully expanded from the tropical to the temperate regions of China via asexual reproduction. During t...

    Authors: Landi Luo, Xiangxiang Kong, Zean Gao, Yan Zheng, Yunqiang Yang, Xiong Li, Danni Yang, Yupeng Geng and Yongping Yang
    Citation: BMC Genomics 2020 21:532
  25. Manila clam (Ruditapes philippinarum) is a worldwide commercially important marine bivalve species. In recent years, however, microbial diseases caused high economic losses and have received increasing attention....

    Authors: Kunyin Jiang, Hongtao Nie, Dongdong Li and Xiwu Yan
    Citation: BMC Genomics 2020 21:531
  26. Studies of leaf shape development and plant stature have made important contributions to the fields of plant breeding and developmental biology. The optimization of leaf morphology and plant height to improve ...

    Authors: Chengwei Huang, Mao Yang, Danlei Shao, Yangming Wang, Shubei Wan, Jianbo He, Zuqing Meng and Rongzhan Guan
    Citation: BMC Genomics 2020 21:530
  27. Genetic improvement of fillet quality attributes is a priority of the aquaculture industry. Muscle composition impacts quality attributes such as flavor, appearance, texture, and juiciness. Fat and moisture ma...

    Authors: Ali Ali, Rafet Al-Tobasei, Daniela Lourenco, Tim Leeds, Brett Kenney and Mohamed Salem
    Citation: BMC Genomics 2020 21:529
  28. The gut bacteria-derived metabolite trimethylamine-N-oxide (TMAO) has been discussed in various cardiometabolic diseases. However, evidence characterizing the microbial population responsible for TMAO accumula...

    Authors: Kun Zuo, Xiaoqing Liu, Pan Wang, Jie Jiao, Chunming Han, Zheng Liu, Xiandong Yin, Jing Li and Xinchun Yang
    Citation: BMC Genomics 2020 21:526
  29. Aquaporins (AQPs), as members of the major intrinsic protein (MIP) superfamily, facilitated the permeation of water and other solutes and are involved in multiple biological processes. AQP family exists in alm...

    Authors: Yanglei Jia and Xiao Liu
    Citation: BMC Genomics 2020 21:525
  30. Paphiopedilum is an important genus of the orchid family Orchidaceae and has high horticultural value. The wild populations are under threat of extinction because of overcollection and habitat destruction. Mature...

    Authors: Lin Fang, Xin Xu, Ji Li, Feng Zheng, Mingzhi Li, Jingwei Yan, Yuan Li, Xinhua Zhang, Lin Li, Guohua Ma, Aying Zhang, Fubing Lv, Kunlin Wu and Songjun Zeng
    Citation: BMC Genomics 2020 21:524
  31. Fruit quality traits have a significant effect on consumer acceptance and subsequently on peach (Prunus persica (L.) Batsch) consumption. Determining the genetic bases of key fruit quality traits is essential for...

    Authors: Zena J. Rawandoozi, Timothy P. Hartmann, Silvia Carpenedo, Ksenija Gasic, Cassia da Silva Linge, Lichun Cai, Eric Van de Weg and David H. Byrne
    Citation: BMC Genomics 2020 21:522
  32. Alcohol dehydrogenases (ADHs) in plants are encoded by a multigene family. ADHs participate in growth, development, and adaptation in many plant species, but the evolution and function of the ADH gene family in s...

    Authors: Weihua Su, Yongjuan Ren, Dongjiao Wang, Yachun Su, Jingfang Feng, Chang Zhang, Hanchen Tang, Liping Xu, Khushi Muhammad and Youxiong Que
    Citation: BMC Genomics 2020 21:521
  33. Chaka sheep, named after Chaka Salt Lake, are adapted to a harsh, highly saline environment. They are known for their high-grade meat quality and are a valuable genetic resource in China. Furthermore, the Chak...

    Authors: Jie Cheng, Huangqing Zhao, Ningbo Chen, Xiukai Cao, Quratulain Hanif, Li Pi, Linyong Hu, Buren Chaogetu, Yongzhen Huang, Xianyong Lan, Chuzhao Lei and Hong Chen
    Citation: BMC Genomics 2020 21:520
  34. Illumina technology currently dominates bacterial genomics due to its high read accuracy and low sequencing cost. However, the incompleteness of draft genomes generated by Illumina reads limits their applicati...

    Authors: Hooman Derakhshani, Steve P. Bernier, Victoria A. Marko and Michael G. Surette
    Citation: BMC Genomics 2020 21:519
  35. Large difference in cerebrum size exist between avian species and populations of the same species and is believed to reflect differences in processing power, i.e. in the speed and efficiency of processing info...

    Authors: Andrey Höglund, Katharina Strempfl, Jesper Fogelholm, Dominic Wright and Rie Henriksen
    Citation: BMC Genomics 2020 21:518
  36. There is a plethora of methods for genome-wide association studies. However, only a few of them may be classified as multi-trait and multi-locus, i.e. consider the influence of multiple genetic variants to sev...

    Authors: Anna A. Igolkina, Georgy Meshcheryakov, Maria V. Gretsova, Sergey V. Nuzhdin and Maria G. Samsonova
    Citation: BMC Genomics 2020 21(Suppl 8):490

    This article is part of a Supplement: Volume 21 Supplement 8

  37. Avian eggs have a proteinaceous cuticle. The quantity of cuticle varies and the deposition of a good cuticle in the uterus (Shell-gland) prevents transmission of bacteria to the egg contents.

    Authors: Sandra Poyatos Pertiñez, Peter W. Wilson, Wiebke Icken, David Cavero, Maureen M. Bain, Anita C. Jones and Ian C. Dunn
    Citation: BMC Genomics 2020 21:516
  38. Gene expression profiles can provide insights into the molecular machinery behind tissue functions and, in turn, can further our understanding of environmental responses, and developmental and evolutionary pro...

    Authors: María Torres-Sánchez, Mark Wilkinson, David J. Gower, Christopher J. Creevey and Diego San Mauro
    Citation: BMC Genomics 2020 21:515
  39. Adaptive Laboratory Evolution (ALE) has emerged as an experimental approach to discover mutations that confer phenotypic functions of interest. However, the task of finding and understanding all beneficial mut...

    Authors: Patrick V. Phaneuf, James T. Yurkovich, David Heckmann, Muyao Wu, Troy E. Sandberg, Zachary A. King, Justin Tan, Bernhard O. Palsson and Adam M. Feist
    Citation: BMC Genomics 2020 21:514
  40. Aim of the present study was first to identify genetic variants associated with egg number (EN) in female broilers, second to describe the mode of their gene action (additive and/or dominant) and third to prov...

    Authors: Eirini Tarsani, Andreas Kranis, Gerasimos Maniatis, Santiago Avendano, Ariadne L. Hager-Theodorides and Antonios Kominakis
    Citation: BMC Genomics 2020 21:512
  41. Domesticated chickens have a wide variety of phenotypes, in contrast with their wild progenitors. Unlike other chicken breeds, Xichuan black-bone chickens have blue-shelled eggs, and black meat, beaks, skin, b...

    Authors: Donghua Li, Guirong Sun, Meng Zhang, Yanfang Cao, Chenxi Zhang, Yawei Fu, Fang Li, Guoxi Li, Ruirui Jiang, Ruili Han, Zhuanjian Li, Yanbin Wang, Yadong Tian, Xiaojun Liu, Wenting Li and Xiangtao Kang
    Citation: BMC Genomics 2020 21:511
  42. Sphingolipids are structural components and signaling molecules in eukaryotic membranes, and many organisms produce compounds that inhibit sphingolipid metabolism. Some of the inhibitors are structurally simil...

    Authors: Hye-Seon Kim, Jessica M. Lohmar, Mark Busman, Daren W. Brown, Todd A. Naumann, Hege H. Divon, Erik Lysøe, Silvio Uhlig and Robert H. Proctor
    Citation: BMC Genomics 2020 21:510

    The Correction to this article has been published in BMC Genomics 2020 21:712

  43. Intensive selection for growth rate (GR) in broiler chickens carries negative after-effects, such as aberrations in skeletal development and the immune system, heart failure, and deterioration of meat quality....

    Authors: Katarzyna Piórkowska, Kacper Żukowski, Katarzyna Połtowicz, Joanna Nowak, Katarzyna Ropka-Molik, Natalia Derebecka, Joanna Wesoły and Dorota Wojtysiak
    Citation: BMC Genomics 2020 21:509

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