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  1. Mammalian hair play an important role in mammals’ ability to adapt to changing climatic environments. The seasonal circulation of yak hair helps them adapt to high altitude but the regulation mechanisms of the...

    Authors: Pengjia Bao, Jiayu Luo, Yanbin Liu, Min Chu, Qingmiao Ren, Xian Guo, Bolin Tang, Xuezhi Ding, Qiang Qiu, Heping Pan, Kun Wang and Ping Yan
    Citation: BMC Genomics 2020 21:355
  2. Species of the genus Vibrio, one of the most diverse bacteria genera, have undergone niche adaptation followed by clonal expansion. Niche adaptation and ultimately the formation of ecotypes and speciation in this...

    Authors: Cynthia Maria Chibani, Olivia Roth, Heiko Liesegang and Carolin Charlotte Wendling
    Citation: BMC Genomics 2020 21:354
  3. The fluctuation of nitrogen (N) contents profoundly affects the root growth and architecture in maize by altering the expression of thousands of genes. The differentially expressed genes (DEGs) in response to ...

    Authors: Yuancong Wang, Jinyan Xu, Min Ge, Lihua Ning, Mengmei Hu and Han Zhao
    Citation: BMC Genomics 2020 21:353
  4. The hybridization of female D. raddei and male D. valentini gave rise to the parthenogenetic Caucasian rock lizard Darevskia unisexualis. A previously identified genetic polymorphism in the species consisted of o...

    Authors: Andrey A. Vergun, Anastasiya E. Girnyk, Vitaly I. Korchagin, Seraphima K. Semyenova, Marine S. Arakelyan, Felix D. Danielyan, Robert W. Murphy and Alexey P. Ryskov
    Citation: BMC Genomics 2020 21:351
  5. The thymus is a highly specialized organ of the immune system where T cell precursors develop and differentiate into self-tolerant CD4+ or CD8+ T cells. No studies to date have investigated how the human trans...

    Authors: Hanna Helgeland, Ingvild Gabrielsen, Helle Akselsen, Arvind Y. M. Sundaram, Siri Tennebø Flåm and Benedicte Alexandra Lie
    Citation: BMC Genomics 2020 21:350
  6. The narrow genetic base of elite germplasm compromises long-term genetic gain and increases the vulnerability to biotic and abiotic stresses in unpredictable environmental conditions. Therefore, an efficient s...

    Authors: Antoine Allier, Simon Teyssèdre, Christina Lehermeier, Laurence Moreau and Alain Charcosset
    Citation: BMC Genomics 2020 21:349
  7. The Intramuscular fat (IMF) content in meat products, which is positively correlated with meat quality, is an important trait considered by consumers. The regulation of IMF deposition is species specific. Howe...

    Authors: Hui Wang, Jincheng Zhong, Chengfu Zhang, Zhixin Chai, Hanwen Cao, Jikun Wang, Jiangjiang Zhu, Jiabo Wang and Qiumei Ji
    Citation: BMC Genomics 2020 21:347
  8. Despite high vaccination coverage using acellular (ACV) and whole-cell pertussis (WCV) vaccines, the resurgence of pertussis is observed globally. Genetic divergence in circulating strains of Bordetella pertussis

    Authors: Shweta Alai, Vikas C. Ghattargi, Manish Gautam, Krunal Patel, Shrikant P. Pawar, Dhiraj P. Dhotre, Umesh Shaligram and Sunil Gairola
    Citation: BMC Genomics 2020 21:345
  9. More teats are necessary for sows to nurse larger litters to provide immunity and nutrient for piglets prior to weaning. Previous studies have reported the strong effect of an insertion mutation in the Vertebr...

    Authors: Zhanwei Zhuang, Rongrong Ding, Longlong Peng, Jie Wu, Yong Ye, Shenping Zhou, Xingwang Wang, Jianping Quan, Enqin Zheng, Gengyuan Cai, Wen Huang, Jie Yang and Zhenfang Wu
    Citation: BMC Genomics 2020 21:344
  10. Heavy metal cadmium (Cd) is a common environmental pollutant in soils, which has an negative impacts on crop growth and development. At present, cadmium has become a major soil and water heavy metal pollutant,...

    Authors: Mingyang Jian, Dazhong Zhang, Xiaoying Wang, Shuwei Wei, Yue Zhao, Qin Ding, Yucui Han and Lingjian Ma
    Citation: BMC Genomics 2020 21:343
  11. Genetic association studies that seek to explain the inheritance of complex traits typically fail to explain a majority of the heritability of the trait under study. Thus, we are left with a gap in the map fro...

    Authors: Benjamin R. Harrison, Lu Wang, Erika Gajda, Elise V. Hoffman, Brian Y. Chung, Scott D. Pletcher, Daniel Raftery and Daniel E. L. Promislow
    Citation: BMC Genomics 2020 21:341
  12. Root systems are critical for plant growth and development. The Casparian strip in root systems is involved in stress resistance and maintaining homeostasis. Casparian strip membrane domain proteins (CASPs) ar...

    Authors: Xiaoyang Wang, Yuanming Zhang, Liyuan Wang, Zhaoe Pan, Shoupu He, Qiong Gao, Baojun Chen, Wenfang Gong and Xiongming Du
    Citation: BMC Genomics 2020 21:340
  13. Schizaphis graminum is one of the most important and devastating cereal aphids worldwide, and its feeding can cause chlorosis and necrosis in wheat. However, little information is available on the wheat defence r...

    Authors: Yong Zhang, Yu Fu, Qian Wang, Xiaobei Liu, Qian Li and Julian Chen
    Citation: BMC Genomics 2020 21:339
  14. Monochamus alternatus Hope is one of the insect vectors of pinewood nematode (Bursaphelenchus xylophilus), which causes the destructive pine wilt disease. The microorganisms within the ecosystem, comprising plant...

    Authors: Yajie Guo, Qiannan Lin, Lyuyi Chen, Rebeca Carballar-Lejarazú, Aishan Zhang, Ensi Shao, Guanghong Liang, Xia Hu, Rong Wang, Lei Xu, Feiping Zhang and Songqing Wu
    Citation: BMC Genomics 2020 21:337
  15. Norway spruce trees in subalpine forests frequently face infections by the needle rust fungus Chrysomyxa rhododendri, which causes significant growth decline and increased mortality of young trees. Yet, it is unk...

    Authors: Carlos Trujillo-Moya, Andrea Ganthaler, Wolfgang Stöggl, Ilse Kranner, Silvio Schüler, Reinhard Ertl, Sarah Schlosser, Jan-Peter George and Stefan Mayr
    Citation: BMC Genomics 2020 21:336
  16. In their paper entitled “Comparative analysis of Faecalibacterium prausnitzii genomes shows a high level of genome plasticity and warrants separation into new species-level taxa” (BMC Genomics (2018) 19:931), Fit...

    Authors: Aharon Oren and George M. Garrity
    Citation: BMC Genomics 2020 21:335

    The original article was published in BMC Genomics 2018 19:931

  17. Recombination plays an important evolutionary role by breaking up haplotypes and shuffling genetic variation. This process impacts the ability of selection to eliminate deleterious mutations or increase the fr...

    Authors: Enrique J. Schwarzkopf, Juan C. Motamayor and Omar E. Cornejo
    Citation: BMC Genomics 2020 21:332
  18. Salivary cell secretion (SCS) plays a critical role in blood feeding by medicinal leeches, making them of use for certain medical purposes even today.

    Authors: Vladislav V. Babenko, Oleg V. Podgorny, Valentin A. Manuvera, Artem S. Kasianov, Alexander I. Manolov, Ekaterina N. Grafskaia, Dmitriy A. Shirokov, Alexey S. Kurdyumov, Dmitriy V. Vinogradov, Anastasia S. Nikitina, Sergey I. Kovalchuk, Nickolay A. Anikanov, Ivan O. Butenko, Olga V. Pobeguts, Daria S. Matyushkina, Daria V. Rakitina…
    Citation: BMC Genomics 2020 21:331

    The Correction to this article has been published in BMC Genomics 2020 21:503

  19. Allopolyploidy is widespread in angiosperms, and they can coordinate two or more different genomes through genetic and epigenetic modifications to exhibit stronger vigor and adaptability. To explore the change...

    Authors: Mengdi Li, Ruihua Wang, Xiaoming Wu and Jianbo Wang
    Citation: BMC Genomics 2020 21:330
  20. Pitayas are currently attracting considerable interest as a tropical fruit with numerous health benefits. However, as a long-day plant, pitaya plants cannot flower in the winter season from November to April i...

    Authors: Rui Xiong, Chengli Liu, Min Xu, Shuang-shuang Wei, Jia-quan Huang and Hua Tang
    Citation: BMC Genomics 2020 21:329
  21. Lactobacillus fermentum, a member of the lactic acid bacteria complex, has recently garnered increased attention due to documented antagonistic properties and interest in assessing the probiotic potential of sele...

    Authors: Katelyn Brandt, Matthew A. Nethery, Sarah O’Flaherty and Rodolphe Barrangou
    Citation: BMC Genomics 2020 21:328
  22. DNA methylation is an epigenetic regulatory form that plays an important role in regulating the gene expression and the tissues development.. However, DNA methylation regulators involved in sheep muscle develo...

    Authors: Yixuan Fan, Yaxu Liang, Kaiping Deng, Zhen Zhang, Guomin Zhang, Yanli Zhang and Feng Wang
    Citation: BMC Genomics 2020 21:327
  23. Balanced complex chromosome rearrangements (BCCR) are balanced chromosomal structural aberrations that involve two or more chromosomes and at least three breakpoints. It is very rare in the population. The obj...

    Authors: Gang Li, Weiyi Shi, Wenbin Niu, Jiawei Xu, Yihong Guo, Yingchun Su and Yingpu Sun
    Citation: BMC Genomics 2020 21:326
  24. Physic nut (Jatropha curcas), an inedible oilseed plant, is among the most promising alternative energy sources because of its high oil content, rapid growth and extensive adaptability. Proteins encoded by MADS-b...

    Authors: Yuehui Tang, Jian Wang, Xinxin Bao, Qian Wu, Tongwen Yang, Han Li, Wenxia Wang, Yizhen Zhang, Nannan Bai, Yaxin Guan, Jiaxi Dai, Yanjie Xie, Shen Li, Rui Huo and Wei Cheng
    Citation: BMC Genomics 2020 21:325
  25. Post-database search is a key procedure in peptide identification with tandem mass spectrometry (MS/MS) strategies for refining peptide-spectrum matches (PSMs) generated by database search engines. Although ma...

    Authors: Xijun Liang, Zhonghang Xia, Ling Jian, Yongxiang Wang, Xinnan Niu and Andrew J. Link
    Citation: BMC Genomics 2020 21:324
  26. Genomic selection (GS) or genomic prediction is considered as a promising approach to accelerate tree breeding and increase genetic gain by shortening breeding cycle, but the efforts to develop routines for op...

    Authors: Linghua Zhou, Zhiqiang Chen, Lars Olsson, Thomas Grahn, Bo Karlsson, Harry X. Wu, Sven-Olof Lundqvist and María Rosario García-Gil
    Citation: BMC Genomics 2020 21:323
  27. Nontuberculous mycobacterium (NTM) species are ubiquitous microorganisms. NTM pulmonary disease (NTM-PD) is thought to be caused not by human-to-human transmission but by independent environmental acquisition....

    Authors: Jung-Ki Yoon, Taek Soo Kim, Jong-Il Kim and Jae-Joon Yim
    Citation: BMC Genomics 2020 21:322
  28. The wide variation in the size of fungal genomes is well known, but the reasons for this size variation are less certain. Here, we present a chromosome-scale assembly of ectophytic Peltaster fructicola, a surface...

    Authors: Bo Wang, Xiaofei Liang, Mark L. Gleason, Tom Hsiang, Rong Zhang and Guangyu Sun
    Citation: BMC Genomics 2020 21:321
  29. Strong artificial and natural selection causes the formation of highly conserved haplotypes that harbor agronomically important genes. GWAS combination with haplotype analysis has evolved as an effective metho...

    Authors: Min Yao, Mei Guan, Zhenqian Zhang, Qiuping Zhang, Yixin Cui, Hao Chen, Wei Liu, Habib U. Jan, Kai P. Voss-Fels, Christian R. Werner, Xin He, Zhongsong Liu, Chunyun Guan, Rod J. Snowdon, Wei Hua and Lunwen Qian
    Citation: BMC Genomics 2020 21:320
  30. Ashbya gossypii naturally overproduces riboflavin and has been utilized for industrial riboflavin production. To improve riboflavin production, various approaches have been developed. In this study, to investigat...

    Authors: Tatsuya Kato, Junya Azegami, Ami Yokomori, Hideo Dohra, Hesham A. El Enshasy and Enoch Y. Park
    Citation: BMC Genomics 2020 21:319
  31. Hypoxia is an important environmental stressor in aquatic ecosystems, with increasingly impacts on global biodiversity. Benthic communities are the most sensitive parts of the coastal ecosystem to eutrophicati...

    Authors: Hongtao Nie, Huamin Wang, Kunyin Jiang and Xiwu Yan
    Citation: BMC Genomics 2020 21:318
  32. Yellow-feathered chickens (YFCs) have a long history in China. They are well-known for the nutritional and commercial importance attributable to their yellow color phenotype. Currently, there is a huge paucity...

    Authors: Xunhe Huang, Newton O. Otecko, Minsheng Peng, Zhuoxian Weng, Weina Li, Jiebo Chen, Ming Zhong, Fusheng Zhong, Sihua Jin, Zhaoyu Geng, Wei Luo, Danlin He, Cheng Ma, Jianlin Han, Sheila C. Ommeh, Yaping Zhang…
    Citation: BMC Genomics 2020 21:316
  33. Climate change, including higher temperatures (HT) has a detrimental impact on wheat productivity and modeling studies predict more frequent heat waves in the future. Wheat growth can be impaired by high dayti...

    Authors: Sumit Pradhan, Md Ali Babar, Guihua Bai, Jahangir Khan, Dipendra Shahi, Muhsin Avci, Jia Guo, Jordan McBreen, Senthold Asseng, Salvador Gezan, Byung-Kee Baik, Ann Blount, Stephen Harrison, Suraj Sapkota, Paul St. Amand and Sanju Kunwar
    Citation: BMC Genomics 2020 21:315
  34. Campylobacter jejuni and Campylobacter coli are major global causes of bacterial gastroenteritis. Whilst several individual colonisation and virulence factors have been identified, our understanding of their role...

    Authors: Jai W. Mehat, Roberto M. La Ragione and Arnoud H. M. van Vliet
    Citation: BMC Genomics 2020 21:314
  35. Grass carp (Ctenopharyngodon idellus) are important species in Asian aquaculture. A draft genome for grass carp has already been published in 2015. However, there is still a requirement for a suitable genetic lin...

    Authors: Xiaoli Huang, Yanxin Jiang, Wanting Zhang, Yingyin Cheng, Yaping Wang, Xiaocui Ma, You Duan, Lei Xia, Yaxin Chen, Nan Wu, Mijuan Shi and Xiao-Qin Xia
    Citation: BMC Genomics 2020 21:313
  36. In gene expression studies, RNA sample pooling is sometimes considered because of budget constraints or lack of sufficient input material. Using microarray technology, RNA sample pooling strategies have been r...

    Authors: Alemu Takele Assefa, Jo Vandesompele and Olivier Thas
    Citation: BMC Genomics 2020 21:312
  37. Puccinellia tenuiflora, a forage grass, is considered a model halophyte given its strong tolerance for multiple stress conditions and its close genetic relationship with cereals. This halophyte has enormous value...

    Authors: Rui Guo, Long Zhao, Kaijian Zhang, Dan Gao and Chunwu Yang
    Citation: BMC Genomics 2020 21:311
  38. The emergence of high throughput technologies that produce vast amounts of genomic data, such as next-generation sequencing (NGS) is transforming biological research. The dramatic increase in the volume of dat...

    Authors: Onur Yukselen, Osman Turkyilmaz, Ahmet Rasit Ozturk, Manuel Garber and Alper Kucukural
    Citation: BMC Genomics 2020 21:310
  39. Aquaculture is a fast-growing industry and therefore welfare and environmental impact have become of utmost importance. Preventing stress associated to common aquaculture practices and optimizing the fish stre...

    Authors: Cláudia Raposo de Magalhães, Denise Schrama, Ana Paula Farinha, Dominique Revets, Annette Kuehn, Sébastien Planchon, Pedro Miguel Rodrigues and Marco Cerqueira
    Citation: BMC Genomics 2020 21:309
  40. Computationally inferred ancestral genomes play an important role in many areas of genome research. We present an improved workflow for the reconstruction from highly diverged genomes such as those of plants.

    Authors: Diego P. Rubert, Fábio V. Martinez, Jens Stoye and Daniel Doerr
    Citation: BMC Genomics 2020 21(Suppl 2):273

    This article is part of a Supplement: Volume 21 Supplement 2

  41. In bacterial genomes, rRNA and tRNA genes are often organized into operons, i.e. segments of closely located genes that share a single promoter and are transcribed as a single unit. Analyzing how these genes a...

    Authors: Tomasz Pawliszak, Meghan Chua, Carson K. Leung and Olivier Tremblay-Savard
    Citation: BMC Genomics 2020 21(Suppl 2):252

    This article is part of a Supplement: Volume 21 Supplement 2

  42. Phylogeny estimation is an important part of much biological research, but large-scale tree estimation is infeasible using standard methods due to computational issues. Recently, an approach to large-scale phy...

    Authors: Vladimir Smirnov and Tandy Warnow
    Citation: BMC Genomics 2020 21(Suppl 2):235

    This article is part of a Supplement: Volume 21 Supplement 2

  43. During cancer progression, malignant cells accumulate somatic mutations that can lead to genetic aberrations. In particular, evolutionary events akin to segmental duplications or deletions can alter the copy-n...

    Authors: Garance Cordonnier and Manuel Lafond
    Citation: BMC Genomics 2020 21(Suppl 2):198

    This article is part of a Supplement: Volume 21 Supplement 2

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