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  1. Though India has sequenced water buffalo genome but its draft assembly is based on cattle genome BTau 4.0, thus de novo chromosome wise assembly is a major pending issue for global community. The existing radiati...

    Authors: Sarika, Vasu Arora, Mir Asif Iquebal, Anil Rai and Dinesh Kumar
    Citation: BMC Genomics 2013 14:43
    Content type: Database Published on:

  2. MicroRNAs (miRNAs) are a family of ~22 nucleotide small RNA molecules that regulate gene expression by fully or partially binding to their complementary sequences. Recently, a large number of miRNAs and their ...

    Authors: Jiajie Sun, Mijie Li, Zhuanjian Li, Jing Xue, Xianyong Lan, Chunlei Zhang, Chuzhao Lei and Hong Chen
    Citation: BMC Genomics 2013 14:42
    Content type: Research article Published on:

  3. Plants such as grapevine (Vitis spp.) display significant inter-cultivar genetic and phenotypic variation. The genetic components underlying phenotypic diversity in grapevine must be understood in order to dis...

    Authors: Luca Venturini, Alberto Ferrarini, Sara Zenoni, Giovanni Battista Tornielli, Marianna Fasoli, Silvia Dal Santo, Andrea Minio, Genny Buson, Paola Tononi, Elisa Debora Zago, Gianpiero Zamperin, Diana Bellin, Mario Pezzotti and Massimo Delledonne
    Citation: BMC Genomics 2013 14:41
    Content type: Research article Published on:

  4. The outer cell wall of the pollen grain (exine) is an extremely resistant structure containing sporopollenin, a mixed polymer made up of fatty acids and phenolic compounds. The synthesis of sporopollenin in th...

    Authors: Gabino Ríos, Francisco R Tadeo, Carmen Leida and María L Badenes
    Citation: BMC Genomics 2013 14:40
    Content type: Research article Published on:

  5. The C. elegans cell fate map, in which the lineage of its approximately 1000 cells is visibly charted beginning from the zygote, represents a developmental biology milestone. Nematode development is invariant fro...

    Authors: Wenyu Zhou, Yunbing Tan, Donovan J Anderson, Eva M Crist, Hannele Ruohola-Baker, Stephen J Salipante and Marshall S Horwitz
    Citation: BMC Genomics 2013 14:39
    Content type: Research article Published on:

  6. Translational and post-translational protein modifications play a key role in the response of plants to pathogen infection. Among the latter, phosphorylation is critical in modulating protein structure, locali...

    Authors: Paolo Margaria, Simona Abbà and Sabrina Palmano
    Citation: BMC Genomics 2013 14:38
    Content type: Research article Published on:

  8. The most important disease of dairy cattle is mastitis, caused by the infection of the mammary gland by various micro-organisms. Although the transcriptional response of bovine mammary gland cells to in vitro inf...

    Authors: Kirsty Jensen, Juliane Günther, Richard Talbot, Wolfram Petzl, Holm Zerbe, Hans-Joachim Schuberth, Hans-Martin Seyfert and Elizabeth J Glass
    Citation: BMC Genomics 2013 14:36
    Content type: Research article Published on:

  9. Proteomics Signature Profiling (PSP) is a novel hit-rate based method that proved useful in resolving consistency and coverage issues in proteomics. As a follow-up study, several points need to be addressed: 1...

    Authors: Wilson Wen Bin Goh, Mengyuan Fan, Hong Sang Low, Marek Sergot and Limsoon Wong
    Citation: BMC Genomics 2013 14:35
    Content type: Research article Published on:

  10. MicroRNAs (miRNAs) regulate gene expression via mRNA cleavage or translation inhibition. In spite of barley being a cereal of great economic importance, very little data is available concerning its miRNA bioge...

    Authors: Katarzyna Kruszka, Andrzej Pacak, Aleksandra Swida-Barteczka, Agnieszka K Stefaniak, Elzbieta Kaja, Izabela Sierocka, Wojciech Karlowski, Artur Jarmolowski and Zofia Szweykowska-Kulinska
    Citation: BMC Genomics 2013 14:34
    Content type: Research article Published on:

  11. Comparative genomics brings insight into sequence evolution, but even more may be learned by coupling sequence analyses with experimental tests of gene function and regulation. However, the reliability of such...

    Authors: Yuanfang Guan, Maitreya J Dunham, Olga G Troyanskaya and Amy A Caudy
    Citation: BMC Genomics 2013 14:33
    Content type: Research article Published on:

  12. The construction of linkage maps is a first step in exploring the genetic basis for adaptive phenotypic divergence in closely related species by quantitative trait locus (QTL) analysis. Linkage maps are also u...

    Authors: Ryo Kakioka, Tomoyuki Kokita, Hiroki Kumada, Katsutoshi Watanabe and Noboru Okuda
    Citation: BMC Genomics 2013 14:32
    Content type: Research article Published on:

  13. Microarray technology is widely utilized for monitoring the expression changes of thousands of genes simultaneously. However, the requirement of relatively large amount of RNA for labeling and hybridization ma...

    Authors: Fugui Wang, Rui Chen, Dong Ji, Shunong Bai, Minping Qian and Minghua Deng
    Citation: BMC Genomics 2013 14:31
    Content type: Research article Published on:

  14. Rubber tree (Hevea brasiliensis) laticifers are the source of natural rubber. Rubber production depends on endogenous and exogenous ethylene (ethephon). AP2/ERF transcription factors, and especially Ethylene-Resp...

    Authors: Cuifang Duan, Xavier Argout, Virginie Gébelin, Marilyne Summo, Jean-François Dufayard, Julie Leclercq, Kuswanhadi, Piyanuch Piyatrakul, Julien Pirrello, Maryannick Rio, Antony Champion and Pascal Montoro
    Citation: BMC Genomics 2013 14:30
    Content type: Research article Published on:

  15. Reaumuria trigyna is an endangered small shrub endemic to desert regions in Inner Mongolia. This dicotyledonous recretohalophyte has unique morphological characteristics that allow it to tolerate the stress impos...

    Authors: Zhen-hua Dang, Lin-lin Zheng, Jia Wang, Zhe Gao, Shu-biao Wu, Zhi Qi and Ying-chun Wang
    Citation: BMC Genomics 2013 14:29
    Content type: Research article Published on:

  16. Red colour in kiwifruit results from the presence of anthocyanin pigments. Their expression, however, is complex, and varies among genotypes, species, tissues and environments. An understanding of the biosynth...

    Authors: Lena G Fraser, Alan G Seal, Mirco Montefiori, Tony K McGhie, Gianna K Tsang, Paul M Datson, Elena Hilario, Hinga E Marsh, Juanita K Dunn, Roger P Hellens, Kevin M Davies, Mark A McNeilage, H Nihal De Silva and Andrew C Allan
    Citation: BMC Genomics 2013 14:28
    Content type: Research article Published on:

  17. Huanglongbing (HLB) is arguably the most destructive disease for the citrus industry. HLB is caused by infection of the bacterium, Candidatus Liberibacter spp. Several citrus GeneChip studies have revealed thousa...

    Authors: Zhi-Liang Zheng and Yihong Zhao
    Citation: BMC Genomics 2013 14:27
    Content type: Research article Published on:

  18. The fertile and sterile plants were derived from the self-pollinated offspring of the F1 hybrid between the novel restorer line NR1 and the Nsa CMS line in Brassica napus. To elucidate gene expression and regulat...

    Authors: Xiaohong Yan, Caihua Dong, Jingyin Yu, Wanghui Liu, Chenghong Jiang, Jia Liu, Qiong Hu, Xiaoping Fang and Wenhui Wei
    Citation: BMC Genomics 2013 14:26
    Content type: Research article Published on:

  19. Both large deletions in genome and heat shock stress would lead to alterations in the gene expression profile; however, whether there is any potential linkage between these disturbances to the transcriptome ha...

    Authors: Bei-Wen Ying, Shigeto Seno, Fuyuro Kaneko, Hideo Matsuda and Tetsuya Yomo
    Citation: BMC Genomics 2013 14:25
    Content type: Research article Published on:

  20. Salinity inhibits growth and development of most plants. The response to salinity is complex and varies between plant organs and stages of development. It involves challenges of ion toxicities and deficiencies...

    Authors: Michael Kravchik and Nirit Bernstein
    Citation: BMC Genomics 2013 14:24
    Content type: Research article Published on:

  21. Apoptosis is a critical process in endothelial cell (EC) biology and pathology, which has been extensively studied at protein level. Numerous gene expression studies of EC apoptosis have also been performed, h...

    Authors: Muna Affara, Debbie Sanders, Hiromitsu Araki, Yoshinori Tamada, Benjamin J Dunmore, Sally Humphreys, Seiya Imoto, Christopher Savoie, Satoru Miyano, Satoru Kuhara, David Jeffries, Cristin Print and D Stephen Charnock-Jones
    Citation: BMC Genomics 2013 14:23
    Content type: Research article Published on:

  22. The genus Spiroplasma contains a group of helical, motile, and wall-less bacteria in the class Mollicutes. Similar to other members of this class, such as the animal-pathogenic Mycoplasma and the plant-pathogenic...

    Authors: Wen-Sui Lo, Ling-Ling Chen, Wan-Chia Chung, Gail E Gasparich and Chih-Horng Kuo
    Citation: BMC Genomics 2013 14:22
    Content type: Research article Published on:

  23. The genome of Fusarium graminearum has been sequenced and annotated previously, but correct gene annotation remains a challenge. In addition, posttranscriptional regulations, such as alternative splicing and RNA ...

    Authors: Chunzhao Zhao, Cees Waalwijk, Pierre J G M de Wit, Dingzhong Tang and Theo van der Lee
    Citation: BMC Genomics 2013 14:21
    Content type: Research article Published on:

  24. The endosymbiont Wolbachia pipientis causes diverse and sometimes dramatic phenotypes in its invertebrate hosts. Four Wolbachia strains sequenced to date indicate that the constitution of the genome is dynamic, b...

    Authors: Anne Duplouy, Iñaki Iturbe-Ormaetxe, Scott A Beatson, Jan M Szubert, Jeremy C Brownlie, Conor J McMeniman, Elizabeth A McGraw, Gregory D D Hurst, Sylvain Charlat, Scott L O’Neill and Megan Woolfit
    Citation: BMC Genomics 2013 14:20
    Content type: Research article Published on:

  25. Heterosis is a phenomenon in which hybrids exhibit superior performance relative to parental phenotypes. In addition to the heterosis of above-ground agronomic traits on which most existing studies have focuse...

    Authors: Rongrong Zhai, Yue Feng, Huimin Wang, Xiaodeng Zhan, Xihong Shen, Weiming Wu, Yingxin Zhang, Daibo Chen, Gaoxing Dai, Zhanlie Yang, Liyong Cao and Shihua Cheng
    Citation: BMC Genomics 2013 14:19
    Content type: Research article Published on:

  26. Biological scientists have long sought after understanding how genes and their structural/functional changes contribute to morphological diversity. Though both grain (BT×623) and sweet (Keller) sorghum lines o...

    Authors: Shu-Ye Jiang, Zhigang Ma, Jeevanandam Vanitha and Srinivasan Ramachandran
    Citation: BMC Genomics 2013 14:18
    Content type: Research article Published on:

  27. Brachiaria ruziziensis is one of the most important forage species planted in the tropics. The application of genomic tools to aid the selection of superior genotypes can provide support to B. ruziziensis breedin...

    Authors: Pedro IT Silva, Alexandre M Martins, Ediene G Gouvea, Marco Pessoa-Filho and Márcio E Ferreira
    Citation: BMC Genomics 2013 14:17
    Content type: Research article Published on:

  28. This study is aimed at the analysis of genetic and physiological effects of myostatin on economically relevant meat quality traits in a genetic background of high muscularity. For this purpose, we generated G3 po...

    Authors: Stefan Kärst, Eva M Strucken, Armin O Schmitt, Alexandra Weyrich, Fernando PM de Villena, Hyuna Yang and Gudrun A Brockmann
    Citation: BMC Genomics 2013 14:16
    Content type: Research article Published on:

  29. Actinobacteria form a major bacterial phylum that includes numerous human pathogens. Actinobacteria are primary contributors to carbon cycling and also represent a primary source of industrial high value produ...

    Authors: Esteban Marcellin, Tim R Mercer, Cuauhtemoc Licona-Cassani, Robin W Palfreyman, Marcel E Dinger, Jennifer A Steen, John S Mattick and Lars K Nielsen
    Citation: BMC Genomics 2013 14:15
    Content type: Research article Published on:

  31. The annotation of many genomes is limited, with a large proportion of identified genes lacking functional assignments. The construction of gene co-expression networks is a powerful approach that presents a way...

    Authors: Dragana Stanley, Nathan S Watson-Haigh, Christopher JE Cowled and Robert J Moore
    Citation: BMC Genomics 2013 14:13
    Content type: Research article Published on:

  32. New sequencing technologies have tremendously increased the number of known molecular markers (single nucleotide polymorphisms; SNPs) in a variety of species. Concurrently, improvements to genotyping technolog...

    Authors: Mikhail Ozerov, Anti Vasemägi, Vidar Wennevik, Eero Niemelä, Sergey Prusov, Matthew Kent and Juha-Pekka Vähä
    Citation: BMC Genomics 2013 14:12
    Content type: Methodology article Published on:

  33. Reduced representation bisulfite sequencing (RRBS) was developed to measure DNA methylation of high-CG regions at single base-pair resolution, and has been widely used because of its minimal DNA requirements a...

    Authors: Junwen Wang, Yudong Xia, Lili Li, Desheng Gong, Yu Yao, Huijuan Luo, Hanlin Lu, Na Yi, Honglong Wu, Xiuqing Zhang, Qian Tao and Fei Gao
    Citation: BMC Genomics 2013 14:11
    Content type: Methodology article Published on:

  34. A reciprocal recurrent selection program has been under way for the Coffea canephora coffee tree for approximately thirty years in the Ivory Coast. Association genetics would help to speed up this program by more...

    Authors: Philippe Cubry, Fabien de Bellis, Komlan Avia, Sophie Bouchet, David Pot, Magali Dufour, Hyacinthe Legnate and Thierry Leroy
    Citation: BMC Genomics 2013 14:10
    Content type: Research article Published on:

  35. Regulatory network of cytoplasmic male sterility (CMS) occurrence is still largely unknown in plants, although numerous researches have been attempted to isolate genes involved in CMS. Here, we employed high-t...

    Authors: Jinghua Yang, Xunyan Liu, Baochen Xu, Na Zhao, Xiaodong Yang and Mingfang Zhang
    Citation: BMC Genomics 2013 14:9
    Content type: Research article Published on:

  36. Subtelomeric multigene families of malaria parasites encode virulent determinants. The published genome sequence of Plasmodium vivax revealed the largest subtelomeric multigene family of human malaria parasites, ...

    Authors: Francisco Javier Lopez, Maria Bernabeu, Carmen Fernandez-Becerra and Hernando A del Portillo
    Citation: BMC Genomics 2013 14:8
    Content type: Research article Published on:

  37. Sequencing technologies have different biases, in single-genome sequencing and metagenomic sequencing; these can significantly affect ORFs recovery and the population distribution of a metagenome. In this pape...

    Authors: Fabio Gori, Susannah G Tringe, Gianluigi Folino, Sacha AFT van Hijum, Huub JM Op den Camp, Mike SM Jetten and Elena Marchiori
    Citation: BMC Genomics 2013 14:7
    Content type: Research article Published on:

  38. The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. Most are integral membrane proteins that transport a b...

    Authors: Gunnar Broehan, Tobias Kroeger, Marcé Lorenzen and Hans Merzendorfer
    Citation: BMC Genomics 2013 14:6
    Content type: Research article Published on:

  40. Cytokine-activated transcription factors from the STAT (Signal Transducers and Activators of Transcription) family control common and context-specific genetic programs. It is not clear to what extent cell-spec...

    Authors: Keunsoo Kang, Gertraud W Robinson and Lothar Hennighausen
    Citation: BMC Genomics 2013 14:4
    Content type: Research article Published on:

  41. Water and nitrogen are two of the most critical inputs required to achieve the high yield potential of modern corn varieties. Under most agricultural settings however they are often scarce and costly. Fortunat...

    Authors: Sabrina Humbert, Sanjeena Subedi, Jonathan Cohn, Bin Zeng, Yong-Mei Bi, Xi Chen, Tong Zhu, Paul D McNicholas and Steven J Rothstein
    Citation: BMC Genomics 2013 14:3
    Content type: Research article Published on:

  42. Rapid development of highly saturated genetic maps aids molecular breeding, which can accelerate gain per breeding cycle in woody perennial plants such as Rubus idaeus (red raspberry). Recently, robust genotyping...

    Authors: Judson A Ward, Jasbir Bhangoo, Felicidad Fernández-Fernández, Patrick Moore, JD Swanson, Roberto Viola, Riccardo Velasco, Nahla Bassil, Courtney A Weber and Daniel J Sargent
    Citation: BMC Genomics 2013 14:2
    Content type: Research article Published on:

  43. Human blood platelets are essential to maintaining normal hemostasis, and platelet dysfunction often causes bleeding or thrombosis. Estimates of genome-wide platelet RNA expression using microarrays have provi...

    Authors: Paul F Bray, Steven E McKenzie, Leonard C Edelstein, Srikanth Nagalla, Kathleen Delgrosso, Adam Ertel, Joan Kupper, Yi Jing, Eric Londin, Phillipe Loher, Huang-Wen Chen, Paolo Fortina and Isidore Rigoutsos
    Citation: BMC Genomics 2013 14:1
    Content type: Research article Published on:

  44. The methylotrophic yeast Pichia pastoris is widely used as a bioengineering platform for producing industrial and biopharmaceutical proteins, studying protein expression and secretion mechanisms, and analyzing me...

    Authors: Shuli Liang, Bin Wang, Li Pan, Yanrui Ye, Minghui He, Shuangyan Han, Suiping Zheng, Xiaoning Wang and Ying Lin
    Citation: BMC Genomics 2012 13:738
    Content type: Research article Published on:

  45. DNA microarrays are used both for research and for diagnostics. In research, Affymetrix arrays are commonly used for genome wide association studies, resequencing, and for gene expression analysis. These array...

    Authors: Yasminka A Jakubek and David J Cutler
    Citation: BMC Genomics 2012 13:737
    Content type: Methodology article Published on:

  46. Rhizobium tropici CIAT 899 and Rhizobium sp. PRF 81 are α-Proteobacteria that establish nitrogen-fixing symbioses with a range of legume hosts. These strains are broadly used in commercial inoculants for applicat...

    Authors: Ernesto Ormeño-Orrillo, Pâmela Menna, Luiz Gonzaga P Almeida, Francisco Javier Ollero, Marisa Fabiana Nicolás, Elisete Pains Rodrigues, Andre Shigueyoshi Nakatani, Jesiane Stefânia Silva Batista, Ligia Maria Oliveira Chueire, Rangel Celso Souza, Ana Tereza Ribeiro Vasconcelos, Manuel Megías, Mariangela Hungria and Esperanza Martínez-Romero
    Citation: BMC Genomics 2012 13:735
    Content type: Research article Published on:

  47. Copy number variation (CNV) is a major source of structural variants and has been commonly identified in mammalian genome. It is associated with gene expression and may present a major genetic component of phe...

    Authors: Congying Chen, Ruimin Qiao, Rongxing Wei, Yuanmei Guo, Huashui Ai, Junwu Ma, Jun Ren and Lusheng Huang
    Citation: BMC Genomics 2012 13:733
    Content type: Research article Published on:

  48. A major goal of the field of systems biology is to translate genome-wide profiling data (e.g., mRNAs, miRNAs) into interpretable functional networks. However, employing a systems biology approach to better und...

    Authors: Seungyoon Nam, Xinghua Long, ChangHyuk Kwon, Sun Kim and Kenneth P Nephew
    Citation: BMC Genomics 2012 13:732
    Content type: Research article Published on:

  49. MicroRNAs (miRNAs) have been implicated in the regulation of milk protein synthesis and development of the mammary gland (MG). However, the specific functions of miRNAs in these regulations are not clear. Ther...

    Authors: Zhen Li, Hongyun Liu, Xiaolu Jin, Lijan Lo and Jianxin Liu
    Citation: BMC Genomics 2012 13:731
    Content type: Research article Published on:

  50. MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression by targeting mRNAs for translation repression or mRNA degradation. Although many miRNAs have been discovered and studied in...

    Authors: Zhen Wang, Kan He, Qishan Wang, Yumei Yang and Yuchun Pan
    Citation: BMC Genomics 2012 13:729
    Content type: Research article Published on:

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BMC Genomics

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