Skip to main content

Articles

Page 269 of 288

  1. MADS-box transcription factors, besides being involved in floral organ specification, have also been implicated in several aspects of plant growth and development. In recent years, there have been reports on g...

    Authors: Rita Arora, Pinky Agarwal, Swatismita Ray, Ashok Kumar Singh, Vijay Pal Singh, Akhilesh K Tyagi and Sanjay Kapoor

    Citation: BMC Genomics 2007 8:242

    Content type: Research article

    Published on:

  2. The family Camelidae that evolved in North America during the Eocene survived with two distinct tribes, Camelini and Lamini. To investigate the evolutionary relationship between them and to further understand ...

    Authors: Peng Cui, Rimutu Ji, Feng Ding, Dan Qi, Hongwei Gao, He Meng, Jun Yu, Songnian Hu and Heping Zhang

    Citation: BMC Genomics 2007 8:241

    Content type: Research article

    Published on:

  3. At present, nothing is known of the role of miRNAs in the immune response in vivo despite the fact that inflammation is thought to underlie multiple acute and chronic diseases. In these circumstances, patients ar...

    Authors: Sterghios A Moschos, Andrew E Williams, Mark M Perry, Mark A Birrell, Maria G Belvisi and Mark A Lindsay

    Citation: BMC Genomics 2007 8:240

    Content type: Research article

    Published on:

  4. Transcriptional profiling after herbivore attack reveals, at the molecular level, how plants respond to this type of biotic stress. Comparing herbivore-induced transcriptional responses of plants with differen...

    Authors: Colette Broekgaarden, Erik H Poelman, Greet Steenhuis, Roeland E Voorrips, Marcel Dicke and Ben Vosman

    Citation: BMC Genomics 2007 8:239

    Content type: Research article

    Published on:

  5. Studies of association methods using DNA pooling of single nucleotide polymorphisms (SNPs) have focused primarily on the effects of "machine-error", number of replicates, and the size of the pool. We use the n...

    Authors: Fei Ji, Stephen J Finch, Chad Haynes, Nancy R Mendell and Derek Gordon

    Citation: BMC Genomics 2007 8:238

    Content type: Methodology article

    Published on:

  6. Abdominal aortic aneurysms are a common disorder with an incompletely understood etiology. We used Illumina and Affymetrix microarray platforms to generate global gene expression profiles for both aneurysmal (...

    Authors: Guy M Lenk, Gerard Tromp, Shantel Weinsheimer, Zoran Gatalica, Ramon Berguer and Helena Kuivaniemi

    Citation: BMC Genomics 2007 8:237

    Content type: Research article

    Published on:

  7. Mutations in the human polycystic kidney disease-1 (hPKD1) gene result in ~85% of cases of autosomal dominant polycystic kidney disease, the most frequent human monogenic disease. PKD1 proteins are large multidom...

    Authors: H Jayantha Gunaratne, Gary W Moy, Masashi Kinukawa, Shinji Miyata, Silvia A Mah and Victor D Vacquier

    Citation: BMC Genomics 2007 8:235

    Content type: Research article

    Published on:

  8. In a mammalian host, the cell surface of African trypanosomes is protected by a monolayer of a single variant surface glycoprotein (VSG). The VSG is central to antigenic variation; one VSG gene is expressed at...

    Authors: O Clyde Hutchinson, Kim Picozzi, Nicola G Jones, Helen Mott, Reuben Sharma, Susan C Welburn and Mark Carrington

    Citation: BMC Genomics 2007 8:234

    Content type: Research article

    Published on:

  9. The CSL (C BF1/RBP-Jκ/S uppressor of Hairless/L AG-1) transcription factor family members are well-known components of the transmembrane receptor Notch signaling pathway, which plays a critical role in metazoan d...

    Authors: Martin Převorovský, František Půta and Petr Folk

    Citation: BMC Genomics 2007 8:233

    Content type: Research article

    Published on:

  10. In situ hybridization (ISH) is a powerful method for visualizing gene expression patterns at the organismal level with cellular resolution. When automated, it is capable of determining the expression of a large n...

    Authors: Murat Cankaya, Ana Martinez Hernandez, Mehmet Ciftci, Sukru Beydemir, Hasan Ozdemir, Harun Budak, Ilhami Gulcin, Veysel Comakli, Tufan Emircupani, Deniz Ekinci, Muslum Kuzu, Qiuhong Jiang, Gregor Eichele and Omer Irfan Kufrevioglu

    Citation: BMC Genomics 2007 8:232

    Content type: Research article

    Published on:

  11. Phylogenetic and functional analysis was conducted on an Anopheles gambiae gene, ENSANGG00000017398. Based on phylogenetic analysis, this gene belongs to the same lineage as Heat shock protein cognate 70-4 (Hsc70...

    Authors: Cheolho Sim, Young S Hong, Konstantin A Tsetsarkin, Dana L Vanlandingham, Stephen Higgs and Frank H Collins

    Citation: BMC Genomics 2007 8:231

    Content type: Research article

    Published on:

  12. Human natural killer (NK) cells are the key contributors of innate immune response and the effector functions of these cells are enhanced by cytokines such as interleukine 2 (IL2). We utilized genome-wide tran...

    Authors: Karen Dybkaer, Javeed Iqbal, Guimei Zhou, Huimin Geng, Li Xiao, Alexander Schmitz, Francesco d'Amore and Wing C Chan

    Citation: BMC Genomics 2007 8:230

    Content type: Research article

    Published on:

  13. The genomes of Streptomyces coelicolor and Streptomyces lividans bear a considerable degree of synteny. While S. coelicolor is the model streptomycete for studying antibiotic synthesis and differentiation, S. liv...

    Authors: Karthik P Jayapal, Wei Lian, Frank Glod, David H Sherman and Wei-Shou Hu

    Citation: BMC Genomics 2007 8:229

    Content type: Research article

    Published on:

  14. Fabaceae (legumes) is one of the largest families of flowering plants, and some members are important crops. In contrast to what we know about their great diversity or economic importance, our knowledge at the...

    Authors: Xianwu Guo, Santiago Castillo-Ramírez, Víctor González, Patricia Bustos, José Luís Fernández-Vázquez, Rosa Isela Santamaría, Jesús Arellano, Miguel A Cevallos and Guillermo Dávila

    Citation: BMC Genomics 2007 8:228

    Content type: Research article

    Published on:

  15. Voltage-gated Na+ channel β1 (Scn1b) subunits are multi-functional proteins that play roles in current modulation, channel cell surface expression, cell adhesion, cell migration, and neurite outgrowth. We have sh...

    Authors: Amanda J Fein, Laurence S Meadows, Chunling Chen, Emily A Slat and Lori L Isom

    Citation: BMC Genomics 2007 8:226

    Content type: Research article

    Published on:

  16. Human rhinoviruses (HRV), the most frequent cause of respiratory infections, include 99 different serotypes segregating into two species, A and B. Rhinoviruses share extensive genomic sequence similarity with ...

    Authors: Caroline Tapparel, Thomas Junier, Daniel Gerlach, Samuel Cordey, Sandra Van Belle, Luc Perrin, Evgeny M Zdobnov and Laurent Kaiser

    Citation: BMC Genomics 2007 8:224

    Content type: Research article

    Published on:

  17. The out of Africa hypothesis has gained generalized consensus. However, many specific questions remain unsettled. To know whether the two M and N macrohaplogroups that colonized Eurasia were already present in...

    Authors: Ana M González, José M Larruga, Khaled K Abu-Amero, Yufei Shi, José Pestano and Vicente M Cabrera

    Citation: BMC Genomics 2007 8:223

    Content type: Research article

    Published on:

  18. Post-puberty deterioration of kidneys is more rapid in males than in females. To reveal the underlying molecular mechanisms for this difference, we analyzed gender-dependent gene expression in kidneys of three...

    Authors: Li Li, Susanne N Boehn, Xiaolei Yu, Qingqin Zhang, Marc Kenzelmann, Dieter Techel, Salah A Mohamed, Petra Jakob, Bettina Kraenzlin, Sigrid Hoffmann and Norbert Gretz

    Citation: BMC Genomics 2007 8:221

    Content type: Research article

    Published on:

  19. Bordetella bronchiseptica is a bacterial respiratory pathogen that infects a broad range of mammals, causing chronic and often subclinical infections. Gene expression in Bordetella is regulated by a two-component...

    Authors: Tracy L Nicholson

    Citation: BMC Genomics 2007 8:220

    Content type: Research article

    Published on:

  20. Three kinases: Sch9, PKA and TOR, are suggested to be involved in both the replicative and chronological ageing in yeast. They function in pathways whose down-regulation leads to life span extension. Several s...

    Authors: Chao Cheng, Paola Fabrizio, Huanying Ge, Valter D Longo and Lei M Li

    Citation: BMC Genomics 2007 8:219

    Content type: Methodology article

    Published on:

  21. Functional and comparative studies of insect genomes have shed light on the complement of genes, which in part, account for shared morphologies, developmental programs and life-histories. Contrasting the gene ...

    Authors: John K Colbourne, Brian D Eads, Joseph Shaw, Elizabeth Bohuski, Darren J Bauer and Justen Andrews

    Citation: BMC Genomics 2007 8:217

    Content type: Research article

    Published on:

  22. To gain insight into host-microbe interactions in a piglet model, a functional genomics approach was used to address the working hypothesis that transcriptionally regulated genes associated with promoting epit...

    Authors: Shankar R Chowdhury, Dale E King, Benjamin P Willing, Mark R Band, Jonathan E Beever, Adrienne B Lane, Juan J Loor, Juan C Marini, Laurie A Rund, Lawrence B Schook, Andrew G Van Kessel and H Rex Gaskins

    Citation: BMC Genomics 2007 8:215

    Content type: Research article

    Published on:

  23. Genetic influences underpinning complex traits are thought to involve multiple quantitative trait loci (QTLs) of small effect size. Detection of such QTL associations requires systematic screening of large num...

    Authors: Sophia J Docherty, Lee M Butcher, Leonard C Schalkwyk and Robert Plomin

    Citation: BMC Genomics 2007 8:214

    Content type: Methodology article

    Published on:

  24. In the Chlorophyta – the green algal phylum comprising the classes Prasinophyceae, Ulvophyceae, Trebouxiophyceae and Chlorophyceae – the chloroplast genome displays a highly variable architecture. While chloro...

    Authors: Jean-Charles de Cambiaire, Christian Otis, Monique Turmel and Claude Lemieux

    Citation: BMC Genomics 2007 8:213

    Content type: Research article

    Published on:

  25. Integrating plant genomics and classical breeding is a challenge for both plant breeders and molecular biologists. Marker-assisted selection (MAS) is a tool that can be used to accelerate the development of no...

    Authors: David Chagné, Charmaine M Carlisle, Céline Blond, Richard K Volz, Claire J Whitworth, Nnadozie C Oraguzie, Ross N Crowhurst, Andrew C Allan, Richard V Espley, Roger P Hellens and Susan E Gardiner

    Citation: BMC Genomics 2007 8:212

    Content type: Research article

    Published on:

  26. The recent discovery of widespread copy number variation in humans has forced a shift away from the assumption of two copies per locus per cell throughout the autosomal genome. In particular, a SNP site can no...

    Authors: Laura E MacConaill, Micheala A Aldred, Xincheng Lu and Thomas LaFramboise

    Citation: BMC Genomics 2007 8:211

    Content type: Research article

    Published on:

  27. The pluripotency and self-renewal capabilities, which define the "stemness" state, of mouse embryonic stem (ES) cells, are usually investigated by functional assays or quantitative measurements of the expressi...

    Authors: Daniel YL Yap, David K Smith, Xue W Zhang and Jeffrey Hill

    Citation: BMC Genomics 2007 8:210

    Content type: Methodology article

    Published on:

  28. To identify as many different transcripts/genes in the Atlantic salmon genome as possible, it is crucial to acquire good cDNA libraries from different tissues and developmental stages, their relevant sequences...

    Authors: Alexei A Adzhubei, Anna V Vlasova, Heidi Hagen-Larsen, Torgeir A Ruden, Jon K Laerdahl and Bjørn Høyheim

    Citation: BMC Genomics 2007 8:209

    Content type: Database

    Published on:

  29. Osteoporosis is frequently observed among aging hens from egg-producing strains (layers) of domestic chicken. White Leghorn (WL) has been intensively selected for egg production and it manifests striking pheno...

    Authors: Carl-Johan Rubin, Johan Lindberg, Carolyn Fitzsimmons, Peter Savolainen, Per Jensen, Joakim Lundeberg, Leif Andersson and Andreas Kindmark

    Citation: BMC Genomics 2007 8:208

    Content type: Research article

    Published on:

  30. The liver is the largest human internal organ – it is composed of multiple cell types and plays a vital role in fulfilling the body's metabolic needs and maintaining homeostasis. Of these cell types the hepato...

    Authors: Jian Huang, Pei Hao, Yun-Li Zhang, Fu-Xing Deng, Qing Deng, Yi Hong, Xiao-Wo Wang, Yun Wang, Ting-Ting Li, Xue-Gong Zhang, Yi-Xue Li, Peng-Yuan Yang, Hong-Yang Wang and Ze-Guang Han

    Citation: BMC Genomics 2007 8:207

    Content type: Research article

    Published on:

  31. Changes in genomic copy number occur in many human diseases including cancer. Characterization of these changes is important for both basic understanding and diagnosis of these diseases. Microarrays have recen...

    Authors: Kyoko Iwao-Koizumi, Kazunori Maekawa, Yohko Nakamura, Sakae Saito, Shoko Kawamoto, Akira Nakagawara and Kikuya Kato

    Citation: BMC Genomics 2007 8:206

    Content type: Methodology article

    Published on:

  32. Glucocorticoids (GCs) are widely used anti-inflammatory drugs. While useful in clinical practice, patients taking GCs often suffer from skeletal side effects including growth retardation in children and adoles...

    Authors: Claudine G James, Veronica Ulici, Jan Tuckermann, T Michael Underhill and Frank Beier

    Citation: BMC Genomics 2007 8:205

    Content type: Research article

    Published on:

  33. Leptospirosis is a world-widely distributed zoonosis. Humans become infected via exposure to pathogenic Leptospira spp. from contaminated water or soil. The availability of genomic sequences of Leptospira interro...

    Authors: Ping He, Yue-Ying Sheng, Yao-Zhou Shi, Xiu-Gao Jiang, Jin-Hong Qin, Zhi-Ming Zhang, Guo-Ping Zhao and Xiao-Kui Guo

    Citation: BMC Genomics 2007 8:204

    Content type: Research article

    Published on:

  34. Honey bees are known for several striking social behaviors, including a complex pattern of behavioral maturation that gives rise to an age-related colony division of labor and a symbolic dance language, by whi...

    Authors: Moushumi Sen Sarma, Charles W Whitfield and Gene E Robinson

    Citation: BMC Genomics 2007 8:202

    Content type: Research article

    Published on:

  35. The Fox gene family comprises a large and functionally diverse group of forkhead-related transcriptional regulators, many of which are essential for metazoan embryogenesis and physiology. Defining conserved funct...

    Authors: Sergey Yaklichkin, Alexander Vekker, Steven Stayrook, Mitchell Lewis and Daniel S Kessler

    Citation: BMC Genomics 2007 8:201

    Content type: Research article

    Published on:

  36. In the post-genomic era, comprehension of cellular processes and systems requires global and non-targeted approaches to handle vast amounts of biological information.

    Authors: Hirokazu Kobayashi, Joe Akitomi, Nobuyuki Fujii, Kazuo Kobayashi, Md Altaf-Ul-Amin, Ken Kurokawa, Naotake Ogasawara and Shigehiko Kanaya

    Citation: BMC Genomics 2007 8:197

    Content type: Research article

    Published on:

  37. Bulked segregant analysis (BSA) identifies molecular markers associated with a phenotype by screening two DNA pools of phenotypically distinct plants for markers with skewed allele frequencies. In contrast to ...

    Authors: Peter Wenzl, Harsh Raman, Junping Wang, Meixue Zhou, Eric Huttner and Andrzej Kilian

    Citation: BMC Genomics 2007 8:196

    Content type: Methodology article

    Published on:

  38. The zebrafish (Danio rerio) is an important vertebrate model organism system for biomedical research. The syntenic conservation between the zebrafish and human genome allows one to investigate the function of hum...

    Authors: Jennifer L Freeman, Adeola Adeniyi, Ruby Banerjee, Stephanie Dallaire, Sean F Maguire, Jianxiang Chi, Bee Ling Ng, Cinthya Zepeda, Carol E Scott, Sean Humphray, Jane Rogers, Yi Zhou, Leonard I Zon, Nigel P Carter, Fengtang Yang and Charles Lee

    Citation: BMC Genomics 2007 8:195

    Content type: Research article

    Published on:

  39. Mammalian angiotensin converting enzyme (ACE) plays a key role in blood pressure regulation. Although multiple ACE-like proteins exist in non-mammalian organisms, to date only one other ACE homologue, ACE2, ha...

    Authors: Monika Rella, Joann L Elliot, Timothy J Revett, Jerry Lanfear, Anne Phelan, Richard M Jackson, Anthony J Turner and Nigel M Hooper

    Citation: BMC Genomics 2007 8:194

    Content type: Research article

    Published on:

  40. Excessive accumulation of lipids in the adipose tissue is a major problem in the present-day broiler industry. However, few studies have analyzed the expression of adipose tissue genes that are involved in pat...

    Authors: Hong-Bao Wang, Hui Li, Qi-Gui Wang, Xin-Yu Zhang, Shou-Zhi Wang, Yu-Xiang Wang and Xiu-Ping Wang

    Citation: BMC Genomics 2007 8:193

    Content type: Research article

    Published on:

Featured videos

View featured videos from across the BMC-series journals

Annual Journal Metrics

Portable peer review

The editors of BMC Genomics support initiatives that expedite the peer review process and are happy to consider manuscripts that have been reviewed in Peerage of Science. Please indicate in your cover letter if this applies to your manuscript.