Skip to main content

Articles

Page 303 of 332

  1. Short non-coding RNAs (ncRNAs) perform their cellular functions in ribonucleoprotein (RNP) complexes, which are also essential for maintaining the stability of the ncRNAs. Depletion of individual protein compo...

    Authors: Muhammad Nauman Aftab, Housheng He, Geir Skogerbø and Runsheng Chen
    Citation: BMC Genomics 2008 9:278
    Content type: Research article Published on:

  2. We describe the development of a novel matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF)-based single nucleotide polymorphism (SNP) scoring strategy, termed Restriction Fragment Mass Polym...

    Authors: Sun Pyo Hong, Seung Il Ji, Hwanseok Rhee, Soo Kyeong Shin, Sun Young Hwang, Seung Hwan Lee, Soong Deok Lee, Heung-Bum Oh, Wangdon Yoo and Soo-Ok Kim
    Citation: BMC Genomics 2008 9:276
    Content type: Methodology article Published on:

  3. Cultivated watermelon form large fruits that are highly variable in size, shape, color, and content, yet have extremely narrow genetic diversity. Whereas a plethora of genes involved in cell wall metabolism, e...

    Authors: W Patrick Wechter, Amnon Levi, Karen R Harris, Angela R Davis, Zhangjun Fei, Nurit Katzir, James J Giovannoni, Ayelet Salman-Minkov, Alvaro Hernandez, Jyothi Thimmapuram, Yaakov Tadmor, Vitaly Portnoy and Tova Trebitsh
    Citation: BMC Genomics 2008 9:275
    Content type: Research article Published on:

  4. The colonial cyanobacterium Microcystis proliferates in a wide range of freshwater ecosystems and is exposed to changing environmental factors during its life cycle. Microcystis blooms are often toxic, potentiall...

    Authors: Lionel Frangeul, Philippe Quillardet, Anne-Marie Castets, Jean-François Humbert, Hans CP Matthijs, Diego Cortez, Andrew Tolonen, Cheng-Cai Zhang, Simonetta Gribaldo, Jan-Christoph Kehr, Yvonne Zilliges, Nadine Ziemert, Sven Becker, Emmanuel Talla, Amel Latifi, Alain Billault…
    Citation: BMC Genomics 2008 9:274
    Content type: Research article Published on:

  5. Studies have shown that genetic and sex differences strongly influence gene expression in mice. Given the diversity and complexity of transcripts produced by alternative splicing, we sought to use microarrays ...

    Authors: Wan-Lin Su, Barmak Modrek, Debraj GuhaThakurta, Stephen Edwards, Jyoti K Shah, Amit V Kulkarni, Archie Russell, Eric E Schadt, Jason M Johnson and John C Castle
    Citation: BMC Genomics 2008 9:273
    Content type: Research article Published on:

  6. In a traditional electrophoresis mobility shift assay (EMSA) a 32P-labeled double-stranded DNA oligonucleotide or a restriction fragment bound to a protein is separated from the unbound DNA by polyacrylamide gel ...

    Authors: Kristel Kaer, Kert Mätlik, Madis Metsis and Mart Speek
    Citation: BMC Genomics 2008 9:272
    Content type: Methodology article Published on:

  7. Biological nitrogen fixation is a prokaryotic process that plays an essential role in the global nitrogen cycle. Azorhizobium caulinodans ORS571 has the dual capacity to fix nitrogen both as free-living organism ...

    Authors: Kyung-Bum Lee, Philippe De Backer, Toshihiro Aono, Chi-Te Liu, Shino Suzuki, Tadahiro Suzuki, Takakazu Kaneko, Manabu Yamada, Satoshi Tabata, Doris M Kupfer, Fares Z Najar, Graham B Wiley, Bruce Roe, Tim T Binnewies, David W Ussery, Wim D'Haeze…
    Citation: BMC Genomics 2008 9:271
    Content type: Research article Published on:

  9. Target genes of a transcription factor (TF) Pou5f1 (Oct3/4 or Oct4), which is essential for pluripotency maintenance and self-renewal of embryonic stem (ES) cells, have previously been identified based on their r...

    Authors: Alexei A Sharov, Shinji Masui, Lioudmila V Sharova, Yulan Piao, Kazuhiro Aiba, Ryo Matoba, Li Xin, Hitoshi Niwa and Minoru SH Ko
    Citation: BMC Genomics 2008 9:269
    Content type: Research article Published on:

  10. Phenotypically identical cells demonstrate predictable, robust behaviours. However, there is uncertainty as to whether phenotypically identical cells are equally similar at the underlying transcriptional level...

    Authors: Tatiana Subkhankulova, Michael J Gilchrist and Frederick J Livesey
    Citation: BMC Genomics 2008 9:268
    Content type: Research article Published on:

  11. To a greater or lesser extent, eukaryotic nuclear genomes contain fragments of their mitochondrial genome counterpart, deriving from the random insertion of damaged mtDNA fragments. NumtS (Nuclear mt Sequences...

    Authors: Daniela Lascaro, Stefano Castellana, Giuseppe Gasparre, Giovanni Romeo, Cecilia Saccone and Marcella Attimonelli
    Citation: BMC Genomics 2008 9:267
    Content type: Research article Published on:

  12. Natural contamination and anthropogenic pollution of soils are likely to be major determinants of functioning and survival of keystone invertebrate taxa. Soil animals will have both evolutionary adaptation and...

    Authors: Jennifer Owen, B Ann Hedley, Claus Svendsen, Jodie Wren, Martijs J Jonker, Peter K Hankard, Linsey J Lister, Stephen R Stürzenbaum, A John Morgan, David J Spurgeon, Mark L Blaxter and Peter Kille
    Citation: BMC Genomics 2008 9:266
    Content type: Research article Published on:

  13. Accurate mRNA splicing depends on multiple regulatory signals encoded in the transcribed RNA sequence. Many examples of mutations within human splice regulatory regions that alter splicing qualitatively or qua...

    Authors: Victoria Nembaware, Bukiwe Lupindo, Katherine Schouest, Charles Spillane, Konrad Scheffler and Cathal Seoighe
    Citation: BMC Genomics 2008 9:265
    Content type: Research article Published on:

  14. Tumor angiogenesis is a highly regulated process involving intercellular communication as well as the interactions of multiple downstream signal transduction pathways. Disrupting one or even a few angiogenesis...

    Authors: Yuefeng Chen, Tao Wei, Lei Yan, Frank Lawrence, Hui-Rong Qian, Timothy P Burkholder, James J Starling, Jonathan M Yingling and Jianyong Shou
    Citation: BMC Genomics 2008 9:264
    Content type: Research article Published on:

  15. Protozoan parasites of the genus Leishmania are causative agents of a diverse spectrum of human diseases collectively known as leishmaniasis. These eukaryotic pathogens that diverged early from the main eukaryoti...

    Authors: Jose M Requena, Cristina Folgueira, Manuel C López and M Carmen Thomas
    Citation: BMC Genomics 2008 9:263
    Content type: Research article Published on:

  16. Peripheral blood mononuclear cells (PBMCs) are relatively easily obtainable cells in humans. Gene expression profiles of PBMCs have been shown to reflect the pathological and physiological state of a person. R...

    Authors: Mark Bouwens, Lydia A Afman and Michael Müller
    Citation: BMC Genomics 2008 9:262
    Content type: Research article Published on:

  17. Integrons are mechanisms that facilitate horizontal gene transfer, allowing bacteria to integrate and express foreign DNA. These are important in the exchange of antibiotic resistance determinants, but can als...

    Authors: Diana R Nemergut, Michael S Robeson, Robert F Kysela, Andrew P Martin, Steven K Schmidt and Rob Knight
    Citation: BMC Genomics 2008 9:261
    Content type: Research article Published on:

  19. Cigarette smoking is a leading cause of preventable death and a significant cause of lung cancer and chronic obstructive pulmonary disease. Prior studies have demonstrated that smoking creates a field of molec...

    Authors: Sriram Sridhar, Frank Schembri, Julie Zeskind, Vishal Shah, Adam M Gustafson, Katrina Steiling, Gang Liu, Yves-Martine Dumas, Xiaohui Zhang, Jerome S Brody, Marc E Lenburg and Avrum Spira
    Citation: BMC Genomics 2008 9:259
    Content type: Research article Published on:

  20. Oligoarrays have become an accessible technique for exploring the transcriptome, but it is presently unclear how absolute transcript data from this technique compare to the data achieved with tag-based quantit...

    Authors: Vigdis Nygaard, Fang Liu, Marit Holden, Winston P Kuo, Jeff Trimarchi, Lucila Ohno-Machado, Connie L Cepko, Arnoldo Frigessi, Ingrid K Glad, Mark A van de Wiel, Eivind Hovig and Heidi Lyng
    Citation: BMC Genomics 2008 9:258
    Content type: Research article Published on:

  21. Metazoan mitochondrial genomes usually consist of the same 37 genes. Such genes contain useful information for phylogenetic analyses and evolution modelling. Although complete mitochondrial genomes have been d...

    Authors: Jin-Shu Yang and Wei-Jun Yang
    Citation: BMC Genomics 2008 9:257
    Content type: Research article Published on:

  22. Rhesus macaques (Macaca mulatta) are the primate most used for biomedical research, but phenotypic differences between Indian-origin and Chinese rhesus macaques have encouraged genetic methods for identifying gen...

    Authors: Jessica A Satkoski, RS Malhi, S Kanthaswamy, RY Tito, VS Malladi and DG Smith
    Citation: BMC Genomics 2008 9:256
    Content type: Research article Published on:

  23. Leishmania parasites cause a diverse spectrum of diseases in humans ranging from spontaneously healing skin lesions (e.g., L. major) to life-threatening visceral diseases (e.g., L. infantum). The high conservatio...

    Authors: Annie Rochette, Frédéric Raymond, Jean-Michel Ubeda, Martin Smith, Nadine Messier, Sébastien Boisvert, Philippe Rigault, Jacques Corbeil, Marc Ouellette and Barbara Papadopoulou
    Citation: BMC Genomics 2008 9:255
    Content type: Research article Published on:

  24. Systematic search for genes whose gain-of-function by exogenous expression confers an advantage in cell-based selective screenings is a powerful method for unbiased functional exploration of the genome, and ha...

    Authors: Maria Luisa Martelli, Claudio Isella, Alessia Mira, Limin Fu, Daniela Cantarella and Enzo Medico
    Citation: BMC Genomics 2008 9:254
    Content type: Methodology article Published on:

  25. microRNAs (miRNAs) are small (~22 nt) non-coding RNAs that regulate cell movement, specification, and development. Expression of miRNAs is highly regulated, both spatially and temporally. Based on direct cloni...

    Authors: Elizabeth J Thatcher, Jordan Bond, Ima Paydar and James G Patton
    Citation: BMC Genomics 2008 9:253
    Content type: Research article Published on:

  26. Genome-wide detection of single feature polymorphisms (SFP) in swine using transcriptome profiling of day 25 placental RNA by contrasting probe intensities from either Meishan or an occidental composite breed ...

    Authors: Steve R Bischoff, Shengdar Tsai, Nicholas E Hardison, Abby M York, Brad A Freking, Dan Nonneman, Gary Rohrer and Jorge A Piedrahita
    Citation: BMC Genomics 2008 9:252
    Content type: Methodology article Published on:

  27. Selenium (Se) is a trace element that occurs in proteins in the form of selenocysteine (Sec) and in tRNAs in the form of selenouridine (SeU). Selenophosphate synthetase (SelD) is required for both utilization ...

    Authors: Yan Zhang, Anton A Turanov, Dolph L Hatfield and Vadim N Gladyshev
    Citation: BMC Genomics 2008 9:251
    Content type: Research article Published on:

  29. The rate at which a stretch of DNA mutates is determined by the cellular systems for DNA replication and repair, and by the nucleotide sequence of the stretch itself. One sequence feature with a particularly s...

    Authors: Roger M Wanner, Carolin Güthlein, Burkhard Springer, Erik C Böttger and Martin Ackermann
    Citation: BMC Genomics 2008 9:249
    Content type: Research article Published on:

  30. MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression by targeting messenger RNAs (mRNAs) and causing mRNA cleavage or translation blockage. Of the 355 Arthropod miRNAs that have been identifie...

    Authors: Ping-an He, Zuoming Nie, Jianqing Chen, Jian Chen, Zhengbing Lv, Qing Sheng, Songping Zhou, Xiaolian Gao, Lingyin Kong, Xiangfu Wu, Yongfeng Jin and Yaozhou Zhang
    Citation: BMC Genomics 2008 9:248
    Content type: Research article Published on:

  31. Bifidobacteria are frequently proposed to be associated with good intestinal health primarily because of their overriding dominance in the feces of breast fed infants. However, clinical feeding studies with ex...

    Authors: Ju-Hoon Lee, VN Karamychev, SA Kozyavkin, D Mills, AR Pavlov, NV Pavlova, NN Polouchine, PM Richardson, VV Shakhova, AI Slesarev, B Weimer and DJ O'Sullivan
    Citation: BMC Genomics 2008 9:247
    Content type: Research article Published on:

  32. Expression levels of mRNA and protein by cell types exhibit a range of correlations for different genes. In this study, we compared levels of mRNA abundance for several cluster designation (CD) genes determine...

    Authors: Laura E Pascal, Lawrence D True, David S Campbell, Eric W Deutsch, Michael Risk, Ilsa M Coleman, Lillian J Eichner, Peter S Nelson and Alvin Y Liu
    Citation: BMC Genomics 2008 9:246
    Content type: Research article Published on:

  33. Since ancient times the filamentous fungus Aspergillus oryzae has been used in the fermentation industry for the production of fermented sauces and the production of industrial enzymes. Recently, the genome seque...

    Authors: Wanwipa Vongsangnak, Peter Olsen, Kim Hansen, Steen Krogsgaard and Jens Nielsen
    Citation: BMC Genomics 2008 9:245
    Content type: Research article Published on:

  35. The medfly, Ceratitis capitata, is a highly invasive agricultural pest that has become a model insect for the development of biological control programs. Despite research into the behavior and classical and popul...

    Authors: Ludvik M Gomulski, George Dimopoulos, Zhiyong Xi, Marcelo B Soares, Maria F Bonaldo, Anna R Malacrida and Giuliano Gasperi
    Citation: BMC Genomics 2008 9:243
    Content type: Research article Published on:

  38. Endothelial differentiation occurs during normal vascular development in the developing embryo. This process is recapitulated in the adult when endothelial progenitor cells are generated in the bone marrow and...

    Authors: Vesna Nikolova-Krstevski, Manoj Bhasin, Hasan H Otu, Towia Libermann and Peter Oettgen
    Citation: BMC Genomics 2008 9:240
    Content type: Research article Published on:

  39. Estrogen receptor positive (ER+) breast cancers (BC) are heterogeneous with regard to their clinical behavior and response to therapies. The ER is currently the best predictor of response to the anti-estrogen ...

    Authors: Sherene Loi, Benjamin Haibe-Kains, Christine Desmedt, Pratyaksha Wirapati, Françoise Lallemand, Andrew M Tutt, Cheryl Gillet, Paul Ellis, Kenneth Ryder, James F Reid, Maria G Daidone, Marco A Pierotti, Els MJJ Berns, Maurice PHM Jansen, John A Foekens, Mauro Delorenzi…
    Citation: BMC Genomics 2008 9:239
    Content type: Research article Published on:

  40. Leishmania (L) are intracellular protozoan parasites that are able to survive and replicate within the harsh and potentially hostile phagolysosomal environment of mammalian mononuclear phagocytes. A complex inter...

    Authors: Fatma Z Guerfali, Dhafer Laouini, Lamia Guizani-Tabbane, Florence Ottones, Khadija Ben-Aissa, Alia Benkahla, Laurent Manchon, David Piquemal, Sondos Smandi, Ons Mghirbi, Thérèse Commes, Jacques Marti and Koussay Dellagi
    Citation: BMC Genomics 2008 9:238
    Content type: Research article Published on:

  41. Genomics of rye (Secale cereale L.) is impeded by its large nuclear genome (1C~7,900 Mbp) with prevalence of DNA repeats (> 90%). An attractive possibility is to dissect the genome to small parts after flow sorti...

    Authors: Hana Šimková, Jan Šafář, Pavla Suchánková, Pavlína Kovářová, Jan Bartoš, Marie Kubaláková, Jaroslav Janda, Jarmila Číhalíková, Rohit Mago, Tamas Lelley and Jaroslav Doležel
    Citation: BMC Genomics 2008 9:237
    Content type: Research article Published on:

  42. Recent analysis of the mouse transcriptional data has revealed the existence of ~34,000 messenger-like non-coding RNAs (ml-ncRNAs). Whereas the functional properties of these ml-ncRNAs are beginning to be unra...

    Authors: Shunmin He, Hua Su, Changning Liu, Geir Skogerbø, Housheng He, Dandan He, Xiaopeng Zhu, Tao Liu, Yi Zhao and Runsheng Chen
    Citation: BMC Genomics 2008 9:236
    Content type: Research article Published on:

  45. In recent years, there have been several sialome projects revealing transcripts expressed in the salivary glands of ticks, which are important vectors of several human diseases. Here, we focused on the sialome...

    Authors: Jindřich Chmelař, Jennifer M Anderson, Jianbing Mu, Ryan C Jochim, Jesus G Valenzuela and Jan Kopecký
    Citation: BMC Genomics 2008 9:233
    Content type: Research article Published on:

  47. The selective absorption of nutrients and other food constituents in the small intestine is mediated by a group of transport proteins and metabolic enzymes, often collectively called 'intestinal barrier protei...

    Authors: Heleen M de Vogel-van den Bosch, Meike Bünger, Philip J de Groot, Hanneke Bosch-Vermeulen, Guido JEJ Hooiveld and Michael Müller
    Citation: BMC Genomics 2008 9:231
    Content type: Research article Published on:

  48. Photorhabdus luminescens is a Gram-negative luminescent enterobacterium and a symbiote to soil nematodes belonging to the species Heterorhabditis bacteriophora. P.luminescens is simultaneously highly pathogenic t...

    Authors: Anna Münch, Lavinia Stingl, Kirsten Jung and Ralf Heermann
    Citation: BMC Genomics 2008 9:229
    Content type: Research article Published on:

  50. Anopheles innate immunity affects Plasmodium development and is a potential target of innovative malaria control strategies. The extent and distribution of nucleotide diversity in immunity genes might provide ins...

    Authors: Anna Cohuet, Sujatha Krishnakumar, Frédéric Simard, Isabelle Morlais, Anastasios Koutsos, Didier Fontenille, Michael Mindrinos and Fotis C Kafatos
    Citation: BMC Genomics 2008 9:227
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • 2022 Citation Impact
    4.4 - 2-year Impact Factor
    4.7 - 5-year Impact Factor
    1.189 - SNIP (Source Normalized Impact per Paper)
    1.107 - SJR (SCImago Journal Rank)

    2023 Speed
    23 days submission to first editorial decision for all manuscripts (Median)
    137 days submission to accept (Median)

    2023 Usage
    7,167,242 downloads
    4,454 Altmetric mentions

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us