Hanahan D, Weinberg RA: The hallmarks of cancer. Cell. 2000, 100 (1): 57-70. 10.1016/S0092-8674(00)81683-9.
Article
CAS
PubMed
Google Scholar
Evan GI, Vousden KH: Proliferation, cell cycle and apoptosis in cancer. Nature. 2001, 411 (6835): 342-348. 10.1038/35077213.
Article
CAS
PubMed
Google Scholar
Ponder BA: Cancer genetics. Nature. 2001, 411 (6835): 336-341. 10.1038/35077207.
Article
CAS
PubMed
Google Scholar
Wechsler-Reya R, Scott MP: The developmental biology of brain tumors. Annu Rev Neurosci. 2001, 24: 385-428. 10.1146/annurev.neuro.24.1.385.
Article
CAS
PubMed
Google Scholar
Kozmik Z, Sure U, Ruedi D, Busslinger M, Aguzzi A: Deregulated expression of PAX5 in medulloblastoma. Proc Natl Acad Sci U S A. 1995, 92 (12): 5709-5713.
Article
PubMed Central
CAS
PubMed
Google Scholar
Rasheed BK, Bigner SH: Genetic alterations in glioma and medulloblastoma. Cancer Metastasis Rev. 1991, 10 (4): 289-299.
Article
CAS
PubMed
Google Scholar
Yokota N, Aruga J, Takai S, Yamada K, Hamazaki M, Iwase T, Sugimura H, Mikoshiba K: Predominant expression of human zic in cerebellar granule cell lineage and medulloblastoma. Cancer Res. 1996, 56 (2): 377-383.
CAS
PubMed
Google Scholar
Holland EC: Brain tumor animal models: importance and progress. Curr Opin Oncol. 2001, 13 (3): 143-147. 10.1097/00001622-200105000-00002.
Article
CAS
PubMed
Google Scholar
Bate M, Martinez-Arias A: The Development of Drosophila melanogaster. Cold Spring Harbor. 1993, Cold Spring Harbor Laboratory Press
Google Scholar
Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF: The Genome Sequence of Drosophila melanogaster. Science. 2000, 287: 2185-2218. 10.1126/science.287.5461.2185.
Article
PubMed
Google Scholar
Rubin GM, Yandell MD, Wortman JR, Gabor Miklos GL, Nelson CR, Hariharan IK, Fortini ME, Li PW, Apweiler R, Fleischmann W: Comparative Genomics of the Eukaryotes. Science. 2000, 287 (5461): 2204-2218. 10.1126/science.287.5461.2204.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fortini ME, Skupski MP, Boguski MS, Hariharan IK: A survey of human disease gene counterparts in the Drosophila genome. J Cell Biol. 2000, 150 (2): F23-30. 10.1083/jcb.150.2.F23.
Article
CAS
PubMed
Google Scholar
Gateff E: Malignant neoplasms of genetic origin in Drosophila melanogaster. Science. 1978, 200 (4349): 1448-1459.
Article
CAS
PubMed
Google Scholar
St John MA, Xu T: Understanding human cancer in a fly?. Am J Hum Genet. 1997, 61 (5): 1006-1010. 10.1086/301619.
Article
PubMed Central
CAS
PubMed
Google Scholar
Pagliarini RA, Xu T: A genetic screen in Drosophila for metastatic behavior. Science. 2003, 302 (5648): 1227-1231. 10.1126/science.1088474.
Article
CAS
PubMed
Google Scholar
Potter CJ, Turenchalk GS, Xu T: Drosophila in cancer research. An expanding role. Trends Genet. 2000, 16 (1): 33-39. 10.1016/S0168-9525(99)01878-8.
Article
CAS
PubMed
Google Scholar
Reiter LT, Potocki L, Chien S, Gribskov M, Bier E: A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res. 2001, 11 (6): 1114-1125. 10.1101/gr.169101.
Article
PubMed Central
CAS
PubMed
Google Scholar
De Lorenzo C, Mechler BM, Bryant PJ: What is Drosophila telling us about cancer?. Cancer Metastasis Rev. 1999, 18 (2): 295-311. 10.1023/A:1006381526008.
Article
CAS
PubMed
Google Scholar
Karim FD, Rubin GM: Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues. Development. 1998, 125 (1): 1-9.
CAS
PubMed
Google Scholar
Lowy DR, Willumsen BM: Function and regulation of ras. Annu Rev Biochem. 1993, 62: 851-891. 10.1146/annurev.bi.62.070193.004223.
Article
CAS
PubMed
Google Scholar
Xu T, Wang W, Zhang S, Stewart RA, Yu W: Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development. 1995, 121 (4): 1053-1063.
CAS
PubMed
Google Scholar
St John MA, Tao W, Fei X, Fukumoto R, Carcangiu ML, Brownstein DG, Parlow AF, McGrath J, Xu T: Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumors and pituitary dysfunction. Nat Genet. 1999, 21 (2): 182-186. 10.1038/5965.
Article
CAS
PubMed
Google Scholar
Xia H, Qi H, Li Y, Pei J, Barton J, Blackstad M, Xu T, Tao W: LATS1 tumor suppressor regulates G2/M transition and apoptosis. Oncogene. 2002, 21 (8): 1233-1241. 10.1038/sj.onc.1205174.
Article
CAS
PubMed
Google Scholar
Turenchalk GS, St John MA, Tao W, Xu T: The role of lats in cell cycle regulation and tumorigenesis. Biochim Biophys Acta. 1999, 1424 (2–3): M9-M16.
CAS
PubMed
Google Scholar
Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber DA, Hariharan IK: salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell. 2002, 110 (4): 467-478. 10.1016/S0092-8674(02)00824-3.
Article
CAS
PubMed
Google Scholar
Torok M, Etkin LD: Two B or not two B? Overview of the rapidly expanding B-box family of proteins. Differentiation. 2001, 67 (3): 63-71. 10.1046/j.1432-0436.2001.067003063.x.
Article
CAS
PubMed
Google Scholar
Jensen K, Shiels C, Freemont PS: PML protein isoforms and the RBCC/TRIM motif. Oncogene. 2001, 20 (49): 7223-7233. 10.1038/sj.onc.1204765.
Article
CAS
PubMed
Google Scholar
Arama E, Dickman D, Kimchie Z, Shearn A, Lev Z: Mutations in the beta-propeller domain of the Drosophila brain tumor (brat) protein induce neoplasm in the larval brain. Oncogene. 2000, 19 (33): 3706-3716. 10.1038/sj.onc.1203706.
Article
CAS
PubMed
Google Scholar
Sonoda J, Wharton RP: Drosophila Brain Tumor is a translational repressor. Genes Dev. 2001, 15 (6): 762-773. 10.1101/gad.870801.
Article
PubMed Central
CAS
PubMed
Google Scholar
Frank DJ, Edgar BA, Roth MB: The Drosophila melanogaster gene brain tumor negatively regulates cell growth and ribosomal RNA synthesis. Development. 2002, 129 (2): 399-407.
CAS
PubMed
Google Scholar
Edwards TA, Wilkinson BD, Wharton RP, Aggarwal AK: Model of the brain tumor-Pumilio translation repressor complex. Genes Dev. 2003, 17 (20): 2508-2513. 10.1101/gad.1119403.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hankins G: Analysis of a Drosophila neuroblastoma gene. PhD thesis Department of Biology, University of Virginia, Charlottesville. 1991, 107-
Google Scholar
Kurzik-Dumke U, Phannavong B, Gundacker D, Gateff E: Genetic, cytogenetic and developmental analysis of the Drosophila melanogaster tumor suppressor gene lethal(2)tumorous imaginal discs (1(2)tid). Differentiation. 1992, 51 (2): 91-104.
Article
CAS
PubMed
Google Scholar
Woodhouse E, Hersperger E, Shearn A: Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes. Dev Genes Evol. 1998, 207 (8): 542-550. 10.1007/s004270050145.
Article
CAS
PubMed
Google Scholar
Bonini NM, Leiserson WM, Benzer S: The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye. Cell. 1993, 72 (3): 379-395. 10.1016/0092-8674(93)90115-7.
Article
CAS
PubMed
Google Scholar
Cutforth T, Gaul U: A methionine aminopeptidase and putative regulator of translation initiation is required for cell growth and patterning in Drosophila. Mech Dev. 1999, 82 (1–2): 23-28. 10.1016/S0925-4773(99)00006-4.
Article
CAS
PubMed
Google Scholar
Alsina B, Corominas M, Berry MJ, Baguna J, Serras F: Disruption of selenoprotein biosynthesis affects cell proliferation in the imaginal discs and brain of Drosophila melanogaster. J Cell Sci. 1999, 112 (Pt 17): 2875-2884.
CAS
PubMed
Google Scholar
Driscoll M, Gerstbrein B: Dying for a cause: invertebrate genetics takes on human neurodegeneration. Nat Rev Genet. 2003, 4 (3): 181-194. 10.1038/nrg1018.
Article
CAS
PubMed
Google Scholar
Saunders RD, Avides MC, Howard T, Gonzalez C, Glover DM: The Drosophila gene abnormal spindle encodes a novel microtubule-associated protein that associates with the polar regions of the mitotic spindle. J Cell Biol. 1997, 137 (4): 881-890. 10.1083/jcb.137.4.881.
Article
PubMed Central
CAS
PubMed
Google Scholar
Dawson IA, Roth S, Akam M, Artavanis-Tsakonas S: Mutations of the fizzy locus cause metaphase arrest in Drosophila melanogaster embryos. Development. 1993, 117 (1): 359-376.
CAS
PubMed
Google Scholar
Scaerou F, Aguilera I, Saunders R, Kane N, Blottiere L, Karess R: The rough deal protein is a new kinetochore component required for accurate chromosome segregation in Drosophila. J Cell Sci. 1999, 112 (Pt 21): 3757-3768.
CAS
PubMed
Google Scholar
Manak JR, Mitiku N, Lipsick JS: Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability. Proc Natl Acad Sci U S A. 2002, 99 (11): 7438-7443. 10.1073/pnas.122231599.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ohnuma S, Philpott A, Harris WA: Cell cycle and cell fate in the nervous system. Curr Opin Neurobiol. 2001, 11 (1): 66-73. 10.1016/S0959-4388(00)00175-6.
Article
CAS
PubMed
Google Scholar
Ohnuma S, Harris WA: Neurogenesis and the cell cycle. Neuron. 2003, 40 (2): 199-208. 10.1016/S0896-6273(03)00632-9.
Article
CAS
PubMed
Google Scholar
Tenev T, Zachariou A, Wilson R, Paul A, Meier P: Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1. Embo J. 2002, 21 (19): 5118-5129. 10.1093/emboj/cdf530.
Article
PubMed Central
CAS
PubMed
Google Scholar
Frank DJ, Roth MB: ncl-1 is required for the regulation of cell size and ribosomal RNA synthesis in Caenorhabditis elegans. J Cell Biol. 1998, 140 (6): 1321-1329. 10.1083/jcb.140.6.1321.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lasko P: The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol. 2000, 150 (2): F51-56. 10.1083/jcb.150.2.F51.
Article
CAS
PubMed
Google Scholar
Lambertsson A: The minute genes in Drosophila and their molecular functions. Adv Genet. 1998, 38: 69-134.
Article
CAS
PubMed
Google Scholar
Andrulis ED, Werner J, Nazarian A, Erdjument-Bromage H, Tempst P, Lis JT: The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila. Nature. 2002, 420 (6917): 837-841. 10.1038/nature01181.
Article
CAS
PubMed
Google Scholar
Mount SM, Salz HK: Pre-messenger RNA processing factors in the Drosophila genome. J Cell Biol. 2000, 150 (2): F37-44. 10.1083/jcb.150.2.F37.
Article
CAS
PubMed
Google Scholar
Schenkel H, Hanke S, De Lorenzo C, Schmitt R, Mechler BM: P elements inserted in the vicinity of or within the Drosophila snRNP SmD3 gene nested in the first intron of the Ornithine Decarboxylase Antizyme gene affect only the expression of SmD3. Genetics. 2002, 161 (2): 763-772.
PubMed Central
CAS
PubMed
Google Scholar
Broadus J, Fuerstenberg S, Doe CQ: Staufen-dependent localization of prospero mRNA contributes to neuroblast daughter-cell fate. Nature. 1998, 391 (6669): 792-795. 10.1038/35861.
Article
CAS
PubMed
Google Scholar
Ito T, Tyler JK, Kadonaga JT: Chromatin assembly factors: a dual function in nucleosome formation and mobilization?. Genes Cells. 1997, 2 (10): 593-600. 10.1046/j.1365-2443.1997.1500348.x.
Article
CAS
PubMed
Google Scholar
Grewal SI, Elgin SC: Heterochromatin: new possibilities for the inheritance of structure. Curr Opin Genet Dev. 2002, 12 (2): 178-187. 10.1016/S0959-437X(02)00284-8.
Article
CAS
PubMed
Google Scholar
Steffensen S, Coelho PA, Cobbe N, Vass S, Costa M, Hassan B, Prokopenko SN, Bellen H, Heck MM, Sunkel CE: A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis. Curr Biol. 2001, 11 (5): 295-307. 10.1016/S0960-9822(01)00096-3.
Article
CAS
PubMed
Google Scholar
Tye BK: MCM proteins in DNA replication. Annu Rev Biochem. 1999, 68: 649-686. 10.1146/annurev.biochem.68.1.649.
Article
CAS
PubMed
Google Scholar
Treisman JE, Follette PJ, O'Farrell PH, Rubin GM: Cell proliferation and DNA replication defects in a Drosophila MCM2 mutant. Genes Dev. 1995, 9 (14): 1709-1715.
Article
CAS
PubMed
Google Scholar
Gerbi SA, Bielinsky AK: DNA replication and chromatin. Curr Opin Genet Dev. 2002, 12 (2): 243-248. 10.1016/S0959-437X(02)00292-7.
Article
CAS
PubMed
Google Scholar
Leatherman JL, Jongens TA: Transcriptional silencing and translational control: key features of early germline development. Bioessays. 2003, 25 (4): 326-335. 10.1002/bies.10247.
Article
CAS
PubMed
Google Scholar
Beltran S, Blanco E, Serras F, Perez-Villamil B, Guigo R, Artavanis-Tsakonas S, Corominas M: Transcriptional network controlled by the trithorax-group gene ash2 in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2003, 100 (6): 3293-3298. 10.1073/pnas.0538075100.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hemavathy K, Ashraf SI, Ip YT: Snail/slug family of repressors: slowly going into the fast lane of development and cancer. Gene. 2000, 257 (1): 1-12. 10.1016/S0378-1119(00)00371-1.
Article
CAS
PubMed
Google Scholar
Rudolph KM, Liaw GJ, Daniel A, Green P, Courey AJ, Hartenstein V, Lengyel JA: Complex regulatory region mediating tailless expression in early embryonic patterning and brain development. Development. 1997, 124 (21): 4297-4308.
CAS
PubMed
Google Scholar
Wallace K, Liu TH, Vaessin H: The pan-neural bHLH proteins DEADPAN and ASENSE regulate mitotic activity and cdk inhibitor dacapo expression in the Drosophila larval optic lobes. Genesis. 2000, 26 (1): 77-85. 10.1002/(SICI)1526-968X(200001)26:1<77::AID-GENE10>3.3.CO;2-I.
Article
CAS
PubMed
Google Scholar
Edenfeld G, Pielage J, Klambt C: Cell lineage specification in the nervous system. Curr Opin Genet Dev. 2002, 12 (4): 473-477. 10.1016/S0959-437X(02)00328-3.
Article
CAS
PubMed
Google Scholar
Hitier R, Chaminade M, Preat T: The Drosophila castor gene is involved in postembryonic brain development. Mech Dev. 2001, 103 (1–2): 3-11. 10.1016/S0925-4773(01)00312-4.
Article
CAS
PubMed
Google Scholar
Saucedo LJ, Edgar BA: Why size matters: altering cell size. Curr Opin Genet Dev. 2002, 12 (5): 565-571. 10.1016/S0959-437X(02)00341-6.
Article
CAS
PubMed
Google Scholar
Skeath JB, Thor S: Genetic control of Drosophila nerve cord development. Curr Opin Neurobiol. 2003, 13 (1): 8-15. 10.1016/S0959-4388(03)00007-2.
Article
CAS
PubMed
Google Scholar
Boquet I, Boujemaa R, Carlier MF, Preat T: Ciboulot regulates actin assembly during Drosophila brain metamorphosis. Cell. 2000, 102 (6): 797-808. 10.1016/S0092-8674(00)00068-4.
Article
CAS
PubMed
Google Scholar
Hassan B, Vaessin H: Regulatory interactions during early neurogenesis in Drosophila. Dev Genet. 1996, 18 (1): 18-27. 10.1002/(SICI)1520-6408(1996)18:1<18::AID-DVG3>3.3.CO;2-6.
Article
CAS
PubMed
Google Scholar
Baker SE, Lorenzen JA, Miller SW, Bunch TA, Jannuzi AL, Ginsberg MH, Perkins LA, Brower DL: Genetic interaction between integrins and moleskin, a gene encoding a Drosophila homolog of importin-7. Genetics. 2002, 162 (1): 285-296.
PubMed Central
CAS
PubMed
Google Scholar
Radtke F, Raj K: The role of Notch in tumorigenesis: oncogene or tumor suppressor?. Nat Rev Cancer. 2003, 3 (10): 756-767. 10.1038/nrc1186.
Article
CAS
PubMed
Google Scholar
Cavallaro U, Christofori G: Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough. Biochim Biophys Acta. 2001, 1552 (1): 39-45. 10.1016/S0304-419X(01)00038-5.
CAS
PubMed
Google Scholar
Tepass U, Tanentzapf G, Ward R, Fehon R: Epithelial cell polarity and cell junctions in Drosophila. Annu Rev Genet. 2001, 35: 747-784. 10.1146/annurev.genet.35.102401.091415.
Article
CAS
PubMed
Google Scholar
Kussel P, Frasch M: Pendulin, a Drosophila protein with cell cycle-dependent nuclear localization, is required for normal cell proliferation. J Cell Biol. 1995, 129 (6): 1491-1507. 10.1083/jcb.129.6.1491.
Article
CAS
PubMed
Google Scholar
El-Husseini AE, Fretier P, Vincent SR: Cloning and characterization of a gene (RNF22) encoding a novel brain expressed ring finger protein (BERP) that maps to human chromosome 11p15.5. Genomics. 2001, 71 (3): 363-367. 10.1006/geno.2000.6452.
Article
CAS
PubMed
Google Scholar
Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S: The tripartite motif family identifies cell compartments. Embo J. 2001, 20 (9): 2140-2151. 10.1093/emboj/20.9.2140.
Article
PubMed Central
CAS
PubMed
Google Scholar
Koi M, Johnson LA, Kalikin LM, Little PF, Nakamura Y, Feinberg AP: Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from chromosome 11. Science. 1993, 260 (5106): 361-364.
Article
CAS
PubMed
Google Scholar
Schiebe M, Ohneseit P, Hoffmann W, Meyermann R, Rodemann HP, Bamberg M: Loss of heterozygosity at 11p15 and p53 alterations in malignant gliomas. J Cancer Res Clin Oncol. 2001, 127 (5): 325-328. 10.1007/s004320000216.
Article
CAS
PubMed
Google Scholar
Ngan ES, Hashimoto Y, Ma ZQ, Tsai MJ, Tsai SY: Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer. Oncogene. 2003, 22 (5): 734-739. 10.1038/sj.onc.1206121.
Article
CAS
PubMed
Google Scholar
Blask DE, Sauer LA, Dauchy RT, Holowachuk EW, Ruhoff MS, Kopff HS: Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. Cancer Res. 1999, 59 (18): 4693-4701.
CAS
PubMed
Google Scholar
Todorov IT, Werness BA, Wang HQ, Buddharaju LN, Todorova PD, Slocum HK, Brooks JS, Huberman JA: HsMCM2/BM28: a novel proliferation marker for human tumors and normal tissues. Lab Invest. 1998, 78 (1): 73-78.
CAS
PubMed
Google Scholar
Levens DL: Reconstructing MYC. Genes Dev. 2003, 17 (9): 1071-1077. 10.1101/gad.1095203.
Article
CAS
PubMed
Google Scholar
Jin J, Harper JW: A license to kill: transcriptional activation and enhanced turnover of Myc by the SCF(kp2) ubiquitin ligase. Cancer Cell. 2003, 3 (6): 517-518. 10.1016/S1535-6108(03)00145-4.
Article
CAS
PubMed
Google Scholar
Zhu Y, Parada LF: The molecular and genetic basis of neurological tumors. Nat Rev Cancer. 2002, 2 (8): 616-626. 10.1038/nrc866.
Article
CAS
PubMed
Google Scholar
Weis K: Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle. Cell. 2003, 112 (4): 441-451. 10.1016/S0092-8674(03)00082-5.
Article
CAS
PubMed
Google Scholar
Ruggero D, Pandolfi PP: Does the ribosome translate cancer?. Nat Rev Cancer. 2003, 3 (3): 179-192. 10.1038/nrc1015.
Article
CAS
PubMed
Google Scholar
Albertson R, Doe CQ: Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry. Nat Cell Biol. 2003, 5 (2): 166-170. 10.1038/ncb922.
Article
CAS
PubMed
Google Scholar
Heisenberg M, Böhl K: Isolation of anatomical brain mutants of Drosophila by histological means. Z Naturforsch. 1979, 34: 143-147.
Google Scholar
Montalta-He H, Leemans R, Loop T, Strahm M, Certa U, Primig M, Acampora D, Simeone A, Reichert H: Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila. Genome Biol. 2002, 3 (4): RESEARCH0015-10.1186/gb-2002-3-4-research0015.
Article
PubMed Central
PubMed
Google Scholar
Kaiser R, Gottschalk G: Elementare Tests zur Beurteilung von Meβbdaten. Bibliographisches Institut Mannheim/Wien/Zürich BI Wissenschaftsverlag. 1972
Google Scholar
Liu G, Loraine AE, Shigeta R, Cline M, Cheng J, Valmeekam V, Sun S, Kulp D, Siani-Rose MA: NetAffx: Affymetrix probesets and annotations. Nucleic Acids Res. 2003, 31 (1): 82-86. 10.1093/nar/gkg121.
Article
PubMed Central
CAS
PubMed
Google Scholar
The FlyBase database of the Drosophila genome projects and community literature. Nucleic Acids Res. 2003, 31 (1): 172-175. 10.1093/nar/gkg094.