Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999–2010. JAMA. 2012;307:483–90.
Article
PubMed
Google Scholar
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011–2012. JAMA. 2014;311:806–14.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ramirez A, Gallion K, Despres C. Latino Childhood Obesity. In: Brennan VM, Kumanyika SK, Zambrana RE, editors. Obesity Interventions in Underserved Communities: Evidence and Directions. Baltimore: The Johns Hopkins University Press; 2014. p. 43–62.
Google Scholar
Hedley AA, Ogden CL, Johnson CL, Carroll MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA. 2004;291(23):2847–50. doi:10.1001/jama.291.23.2847.
May AL, Pan L, Sherry B, Blanck HM, Galuska D, Dalenius K, Polhamus B, Kettel-Khan L, Grummer-Strawn LM. Vital signs: obesity among low-income, preschool-aged children--United States, 2008–2011. MMWR Morb Mortal Wkly Rep. 2013;62:629–34.
Google Scholar
Parsons TJ, Power C, Manor O. Fetal and early life growth and body mass index from birth to early adulthood in 1958 British cohort: longitudinal study. BMJ. 2001;323:1331–5.
Article
CAS
PubMed
PubMed Central
Google Scholar
Grissom NM, Reyes TM. Gestational overgrowth and undergrowth affect neurodevelopment: similarities and differences from behavior to epigenetics. Int J Dev Neurosci. 2013;31:406–14.
Article
CAS
PubMed
Google Scholar
Miller GE, Chen E, Parker KJ. Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms. Psychol Bull. 2011;137:959–97.
Article
PubMed
PubMed Central
Google Scholar
Liu X, Chen Q, Tsai HJ, Wang G, Hong X, Zhou Y, et al. Maternal preconception body mass index and offspring cord blood DNA methylation: exploration of early life origins of disease. Environ Mol Mutagen. 2014;55:223–30.
Article
CAS
PubMed
Google Scholar
Dubois L, Ohm Kyvik K, Girard M, Tatone-Tokuda F, Perusse D, Hjelmborg J, et al. Genetic and environmental contributions to weight, height, and BMI from birth to 19 years of age: an international study of over 12,000 twin pairs. PLoS One. 2012;7:e30153.
Article
CAS
PubMed
PubMed Central
Google Scholar
Breton C. The hypothalamus-adipose axis is a key target of developmental programming by maternal nutritional manipulation. J Endocrinol. 2013;216:R19–31.
Article
CAS
PubMed
Google Scholar
Bouchard L, Rabasa-Lhoret R, Faraj M, Lavoie ME, Mill J, Perusse L, et al. Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction. Am J Clin Nutr. 2010;91:309–20.
Article
CAS
PubMed
Google Scholar
Knittle JL, Timmers K, Ginsberg-Fellner F, Brown RE, Katz DP. The growth of adipose tissue in children and adolescents. Cross-sectional and longitudinal studies of adipose cell number and size. J Clin Invest. 1979;63:239–46.
Article
CAS
PubMed
PubMed Central
Google Scholar
Brune BC, Gerlach MK, Seewald MJ, Brune TG. Early postnatal BMI adaptation is regulated during a fixed time period and mainly depends on maternal BMI. Obesity (Silver Spring). 2010;18:798–802.
Article
Google Scholar
Barroso CS, Roncancio A, Hinojosa MB, Reifsnider E. The association between early childhood overweight and maternal factors. Child Obes. 2012;8:449–54.
Article
PubMed
PubMed Central
Google Scholar
Mamun AA, O'Callaghan MJ, Williams GM, Najman JM. Change in maternal body mass index is associated with offspring body mass index: a 21-year prospective study. Eur J Nutr. 2013;52:1597–606.
Article
PubMed
Google Scholar
Feinberg AP. Epigenetics at the epicenter of modern medicine. JAMA. 2008;299:1345–50.
Article
CAS
PubMed
Google Scholar
Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A. 2005;102:10604–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Herrera BM, Keildson S, Lindgren CM. Genetics and epigenetics of obesity. Maturitas. 2011;69:41–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hillier TA, Pedula KL, Schmidt MM, Mullen JA, Charles MA, Pettitt DJ. Childhood obesity and metabolic imprinting: the ongoing effects of maternal hyperglycemia. Diabetes Care. 2007;30:2287–92.
Article
PubMed
Google Scholar
Ornoy A. Growth and neurodevelopmental outcome of children born to mothers with pregestational and gestational diabetes. Pediatr Endocrinol Rev. 2005;3:104–13.
PubMed
Google Scholar
Godfrey KM, Sheppard A, Gluckman PD, Lillycrop KA, Burdge GC, McLean C, et al. Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes. 2011;60:1528–34.
Article
CAS
PubMed
PubMed Central
Google Scholar
Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci U S A. 2008;105:17046–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hochberg Z, Feil R, Constancia M, Fraga M, Junien C, Carel JC, et al. Child health, developmental plasticity, and epigenetic programming. Endocr Rev. 2011;32:159–224.
Article
CAS
PubMed
Google Scholar
Sorensen HT, Sabroe S, Rothman KJ, Gillman M, Fischer P, Sorensen TI. Relation between weight and length at birth and body mass index in young adulthood: cohort study. BMJ. 1997;315:1137.
Article
CAS
PubMed
PubMed Central
Google Scholar
Whitaker RC, Pepe MS, Wright JA, Seidel KD, Dietz WH. Early adiposity rebound and the risk of adult obesity. Pediatrics. 1998;101:E5.
Article
CAS
PubMed
Google Scholar
Thompson TM, Sharfi D, Lee M, Yrigollen CM, Naumova OY, Grigorenko EL. Comparison of whole-genome DNA methylation patterns in whole blood, saliva, and lymphoblastoid cell lines. Behav Genet. 2013;43:168–76.
Article
PubMed
Google Scholar
Abraham JE, Maranian MJ, Spiteri I, Russell R, Ingle S, Luccarini C, et al. Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping. BMC Med Genomics. 2012;5:19.
Article
CAS
PubMed
PubMed Central
Google Scholar
Thiede C, Prange-Krex G, Freiberg-Richter J, Bornhauser M, Ehninger G. Buccal swabs but not mouthwash samples can be used to obtain pretransplant DNA fingerprints from recipients of allogeneic bone marrow transplants. Bone Marrow Transplant. 2000;25:575–7.
Article
CAS
PubMed
Google Scholar
Segata N, Haake SK, Mannon P, Lemon KP, Waldron L, Gevers D, et al. Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples. Genome Biol. 2012;13:R42.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wu HC, Wang Q, Chung WK, Andrulis IL, Daly MB, John EM, et al. Correlation of DNA methylation levels in blood and saliva DNA in young girls of the LEGACY Girls study. Epigenetics. 2014;9:929–33.
Article
PubMed
PubMed Central
Google Scholar
Wang D, Liu X, Zhou Y, Xie H, Hong X, Tsai HJ, et al. Individual variation and longitudinal pattern of genome-wide DNA methylation from birth to the first two years of life. Epigenetics. 2012;7:594–605.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hindorff LA MJ, Morales J, Junkins HA, Hall PN, Klemm AK, and Manolio TA. A Catalog of Published Genome-Wide Association Studies. Available at: www.genome.gov/gwastudies. Accessed 6 Dec 2015.
Po’e EK, Heerman WJ, Mistry RS, Barkin SL. Growing Right Onto Wellness (GROW): a family-centered, community-based obesity prevention randomized controlled trial for preschool child–parent pairs. Contemp Clin Trials. 2013;36:436–49.
Article
PubMed
Google Scholar
National Center for Health Statistics and the National Center for Chronic Disease Prevention and Health Promotion. 2000 CDC Growth Charts for the United States: Methods and Development. 2002;11:246.
Pryor LE, Tremblay RE, Boivin M, Touchette E, Dubois L, Genolini C, et al. Developmental trajectories of body mass index in early childhood and their risk factors: an 8-year longitudinal study. Arch Pediatr Adolesc Med. 2011;165:906–12.
Article
PubMed
Google Scholar
Barkin SL, Gesell SB, Po’e EK, Escarfuller J, Tempesti T. Culturally Tailored, Family-Centered, Behavioral Obesity Intervention for Latino-American Preschool-aged Children. Pediatrics. 2012;130:445–56.
Article
PubMed
PubMed Central
Google Scholar
Robinson TN, Matheson DM, Kraemer HC, Wilson DM, Obarzanek E, Thompson NS, et al. A Randomized Controlled Trial of Culturally Tailored Dance and Reducing Screen Time to Prevent Weight Gain in Low-Income African American Girls: Stanford GEMS. Arch Pediatr Adolesc Med. 2010;164:995–1004.
Article
PubMed
PubMed Central
Google Scholar
Nunes AP, Oliveira IO, Santos BR, Millech C, Silva LP, Gonzalez DA, et al. Quality of DNA extracted from saliva samples collected with the Oragene DNA self-collection kit. BMC Med Res Methodol. 2012;12:65.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ng DP, Koh D, Choo S, Chia KS. Saliva as a viable alternative source of human genomic DNA in genetic epidemiology. Clin Chim Acta. 2006;367:81–5.
Article
CAS
PubMed
Google Scholar
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, et al. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. PLoS One. 2012;7:e51954.
Article
CAS
PubMed
PubMed Central
Google Scholar
Illumina Inc. Infinium HumanMethylation450 BeadChip Kit. 2015
Sandoval J, Heyn H, Moran S, Serra-Musach J, Pujana MA, Bibikova M, et al. Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics. 2011;6:692–702.
Article
CAS
PubMed
Google Scholar
Bibikova M, Fan JB. GoldenGate assay for DNA methylation profiling. Methods Mol Biol. 2009;507:149–63.
Article
CAS
PubMed
Google Scholar
Dedeurwaerder S, Defrance M, Bizet M, Calonne E, Bontempi G, Fuks F. A comprehensive overview of Infinium HumanMethylation450 data processing. Brief Bioinform. 2014;15:929–41.
Article
PubMed
Google Scholar
Chen YA, Lemire M, Choufani S, Butcher DT, Grafodatskaya D, Zanke BW, et al. Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray. Epigenetics. 2013;8:203–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zou H, Hastie T. Regularization and variable selection via the elastic net. J Roy Stat Soc B. 2005;67:768.
Article
Google Scholar
Anjum S, Fourkala EO, Zikan M, Wong A, Gentry-Maharaj A, Jones A, et al. A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival. Genome Med. 2014;6:47.
Article
PubMed
PubMed Central
CAS
Google Scholar
Schmutz M, Zucknick M, Schlenk RF, Döhner K, Döhner H, Plass C, et al. Differential DNA Methylation Predicts Response To Combined Treatment Regimens With a DNA Methyltransferase Inhibitor In Acute Myeloid Leukemia (AML). Blood. 2013;122:2539.
Article
CAS
Google Scholar
Wilhelm-Benartzi CS, Koestler DC, Karagas MR, Flanagan JM, Christensen BC, Kelsey KT, et al. Review of processing and analysis methods for DNA methylation array data. Br J Cancer. 2013;109:1394–402.
Article
CAS
PubMed
PubMed Central
Google Scholar
Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14:R115.
Article
PubMed
PubMed Central
Google Scholar
Hochberg Y. A sharper Bonferroni procedure for multiple tests of significance. Biometricka. 1988;75:800–2.
Article
Google Scholar
Zhu S, Heymsfield SB, Toyoshima H, Wang Z, Pietrobelli A, Heshka S. Race-ethnicity-specific waist circumference cutoffs for identifying cardiovascular disease risk factors. Am J Clin Nutr. 2005;81:409–15.
CAS
PubMed
Google Scholar
Colin Bell A, Adair LS, Popkin BM. Ethnic differences in the association between body mass index and hypertension. Am J Epidemiol. 2002;155:346–53.
Article
CAS
PubMed
Google Scholar
Misra A, Wasir JS, Vikram NK. Waist circumference criteria for the diagnosis of abdominal obesity are not applicable uniformly to all populations and ethnic groups. Nutrition. 2005;21:969–76.
Article
PubMed
Google Scholar
Kramer A, Green J, Pollard Jr J, Tugendreich S. Causal analysis approaches in Ingenuity Pathway Analysis. Bioinformatics. 2014;30:523–30.
Article
PubMed
CAS
Google Scholar
Jo H, Schieve LA, Sharma AJ, Hinkle SN, Li R, Lind JN. Maternal prepregnancy body mass index and child psychosocial development at 6 years of age. Pediatrics. 2015;135:e1198–1209.
Article
PubMed
PubMed Central
Google Scholar
Manu P, Dima L, Shulman M, Vancampfort D, De Hert M, Correll CU. Weight gain and obesity in schizophrenia: epidemiology, pathobiology, and management. Acta Psychiatr Scand. 2015;132:97–108.
Article
CAS
PubMed
Google Scholar
Elshorbagy AK, Kozich V, Smith AD, Refsum H. Cysteine and obesity: consistency of the evidence across epidemiologic, animal and cellular studies. Curr Opin Clin Nutr Metab Care. 2012;15:49–57.
Article
CAS
PubMed
Google Scholar
Elshorbagy AK, Valdivia-Garcia M, Refsum H, Butte N. The association of cysteine with obesity, inflammatory cytokines and insulin resistance in Hispanic children and adolescents. PLoS One. 2012;7:e44166.
Article
CAS
PubMed
PubMed Central
Google Scholar
Vaya A, Rivera L, Hernandez-Mijares A, de la Fuente M, Sola E, Romagnoli M, et al. Homocysteine levels in morbidly obese patients: its association with waist circumference and insulin resistance. Clin Hemorheol Microcirc. 2012;52:49–56.
CAS
PubMed
Google Scholar
Plaisance EP, Greenway FL, Boudreau A, Hill KL, Johnson WD, Krajcik RA, et al. Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome. J Clin Endocrinol Metab. 2011;96:E836–840.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yoshino J, Klein S. A novel link between circadian clocks and adipose tissue energy metabolism. Diabetes. 2013;62:2175–7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Souren NY, Tierling S, Fryns JP, Derom C, Walter J, Zeegers MP. DNA methylation variability at growth-related imprints does not contribute to overweight in monozygotic twins discordant for BMI. Obesity (Silver Spring). 2011;19:1519–22.
Article
CAS
Google Scholar
Wu Y, Zhou S, Smas CM. Downregulated expression of the secreted glycoprotein follistatin-like 1 (Fstl1) is a robust hallmark of preadipocyte to adipocyte conversion. Mech Dev. 2010;127:183–202.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fan N, Sun H, Wang Y, Zhang L, Xia Z, Peng L, et al. Follistatin-like 1: a potential mediator of inflammation in obesity. Mediators Inflamm. 2013;2013:752519.
Article
PubMed
PubMed Central
CAS
Google Scholar
Schmidt V, Willnow TE. Protein sorting gone wrong - VPS10P domain receptors in cardiovascular and metabolic diseases. Atherosclerosis. 2016;245:194–9.
Article
CAS
PubMed
Google Scholar
Goodarzi MO, Lehman DM, Taylor KD, Guo X, Cui J, Quinones MJ, et al. SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse. Diabetes. 2007;56:1922–9.
Article
CAS
PubMed
Google Scholar
Paterson AD, Waggott D, Boright AP, Hosseini SM, Shen E, Sylvestre MP, et al. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. Diabetes. 2010;59:539–49.
Article
CAS
PubMed
Google Scholar
Granhall C, Park HB, Fakhrai-Rad H, Luthman H. High-resolution quantitative trait locus analysis reveals multiple diabetes susceptibility loci mapped to intervals < 800 kb in the species-conserved Niddm1i of the GK rat. Genetics. 2006;174:1565–72.
Article
CAS
PubMed
PubMed Central
Google Scholar
Donohoe G, Morris DW, Corvin A. The psychosis susceptibility gene ZNF804A: associations, functions, and phenotypes. Schizophr Bull. 2010;36:904–9.
Article
PubMed
PubMed Central
Google Scholar
Girgenti MJ, LoTurco JJ, Maher BJ. ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2. PLoS One. 2012;7:e32404.
Article
CAS
PubMed
PubMed Central
Google Scholar
Balog Z, Kiss I, Keri S. ZNF804A may be associated with executive control of attention. Genes Brain Behav. 2011;10:223–7.
Article
CAS
PubMed
Google Scholar
Donohoe G, Rose E, Frodl T, Morris D, Spoletini I, Adriano F, et al. ZNF804A risk allele is associated with relatively intact gray matter volume in patients with schizophrenia. Neuroimage. 2011;54:2132–7.
Article
CAS
PubMed
Google Scholar
Lencz T, Szeszko PR, DeRosse P, Burdick KE, Bromet EJ, Bilder RM, et al. A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypes. Neuropsychopharmacology. 2010;35:2284–91.
Article
CAS
PubMed
PubMed Central
Google Scholar
Berkel S, Marshall CR, Weiss B, Howe J, Roeth R, Moog U, et al. Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation. Nat Genet. 2010;42:489–91.
Article
CAS
PubMed
Google Scholar
Berkel S, Tang W, Trevino M, Vogt M, Obenhaus HA, Gass P, et al. Inherited and de novo SHANK2 variants associated with autism spectrum disorder impair neuronal morphogenesis and physiology. Hum Mol Genet. 2012;21:344–57.
Article
CAS
PubMed
Google Scholar
Kumar RA. SHANK2 redemption: another synaptic protein for mental retardation and autism. Clin Genet. 2010;78:519–21.
Article
CAS
PubMed
Google Scholar
Won H, Lee HR, Gee HY, Mah W, Kim JI, Lee J, et al. Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature. 2012;486:261–5.
Article
CAS
PubMed
Google Scholar
Leblond CS, Heinrich J, Delorme R, Proepper C, Betancur C, Huguet G, et al. Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. PLoS Genet. 2012;8:e1002521.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tse MT. Neurodevelopmental disorders: exploring the links between SHANK2 and autism. Nat Rev Drug Discov. 2012;11:518.
Article
CAS
PubMed
Google Scholar
Liu Y, Niu N, Zhu X, Du T, Wang X, Chen D, et al. Genetic variation and association analyses of the nuclear respiratory factor 1 (nRF1) gene in Chinese patients with type 2 diabetes. Diabetes. 2008;57:777–82.
Article
CAS
PubMed
Google Scholar
Qu L, He B, Pan Y, Xu Y, Zhu C, Tang Z, et al. Association between polymorphisms in RAPGEF1, TP53, NRF1 and type 2 diabetes in Chinese Han population. Diabetes Res Clin Pract. 2011;91:171–6.
Article
CAS
PubMed
Google Scholar
van Tienen FH, Lindsey PJ, van der Kallen CJ, Smeets HJ. Prolonged Nrf1 overexpression triggers adipocyte inflammation and insulin resistance. J Cell Biochem. 2010;111:1575–85.
Article
PubMed
CAS
Google Scholar
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci U S A. 2003;100:8466–71.
Article
CAS
PubMed
PubMed Central
Google Scholar
McGovern DP, Gardet A, Torkvist L, Goyette P, Essers J, Taylor KD, et al. Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet. 2010;42:332–7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sabin MA, Werther GA, Kiess W. Genetics of obesity and overgrowth syndromes. Best Pract Res Clin Endocrinol Metab. 2011;25:207–20.
Article
CAS
PubMed
Google Scholar
Ignoul S, Eggermont J. CBS domains: structure, function, and pathology in human proteins. Am J Physiol Cell Physiol. 2005;289:C1369–1378.
Article
CAS
PubMed
Google Scholar
Picker JD, Levy HL. Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency. In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, et al., editors. GeneReviews(R). Seattle (WA) 1993.
Liao YC, Lo SH. Deleted in liver cancer-1 (DLC-1): a tumor suppressor not just for liver. Int J Biochem Cell Biol. 2008;40:843–7.
Article
CAS
PubMed
Google Scholar
Xue W, Krasnitz A, Lucito R, Sordella R, Vanaelst L, Cordon-Cardo C, et al. DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes Dev. 2008;22:1439–44.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wong CC, Wong CM, Ko FC, Chan LK, Ching YP, Yam JW, et al. Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma. PLoS One. 2008;3:e2779.
Article
PubMed
PubMed Central
CAS
Google Scholar
Wong CM, Yam JW, Ching YP, Yau TO, Leung TH, Jin DY, et al. Rho GTPase-activating protein deleted in liver cancer suppresses cell proliferation and invasion in hepatocellular carcinoma. Cancer Res. 2005;65:8861–8.
Article
CAS
PubMed
Google Scholar
Tripathi V, Popescu NC, Zimonjic DB. DLC1 interaction with alpha-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activity. Mol Cell Biol. 2012;32:2145–59.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gong EY, Park E, Lee HJ, Lee K. Expression of Atp8b3 in murine testis and its characterization as a testis specific P-type ATPase. Reproduction. 2009;137:345–51.
Article
CAS
PubMed
Google Scholar
Folmer DE, Elferink RP, Paulusma CC. P4 ATPases - lipid flippases and their role in disease. Biochim Biophys Acta. 2009;1791:628–35.
Article
CAS
PubMed
Google Scholar
Harris MJ, Arias IM. FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body. Biochim Biophys Acta. 2003;1633:127–31.
Article
CAS
PubMed
Google Scholar
Cheng IK, Ching AK, Chan TC, Chan AW, Wong CK, Choy KW, et al. Reduced CRYL1 expression in hepatocellular carcinoma confers cell growth advantages and correlates with adverse patient prognosis. J Pathol. 2010;220:348–60.
CAS
PubMed
Google Scholar
Chen CF, Yeh SH, Chen DS, Chen PJ, Jou YS. Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11. Genes Chromosomes Cancer. 2005;44:320–8.
Article
CAS
PubMed
Google Scholar
Park KS, Shin HD, Park BL, Cheong HS, Cho YM, Lee HK, et al. Putative association of peroxisome proliferator-activated receptor gamma co-activator 1beta (PPARGC1B) polymorphism with Type 2 diabetes mellitus. Diabet Med. 2006;23:635–42.
Article
CAS
PubMed
Google Scholar
Andersen G, Wegner L, Yanagisawa K, Rose CS, Lin J, Glumer C, et al. Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity. J Med Genet. 2005;42:402–7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Queiroz EM, Candido AP, Castro IM, Bastos AQ, Machado-Coelho GL, Freitas RN. IGF2, LEPR, POMC, PPARG, and PPARGC1 gene variants are associated with obesity-related risk phenotypes in Brazilian children and adolescents. Braz J Med Biol Res. 2015;48:595–602.
Article
CAS
PubMed
PubMed Central
Google Scholar
Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011;43:977–83.
Heinrich A, Lourdusamy A, Tzschoppe J, Vollstadt-Klein S, Buhler M, Steiner S, et al. The risk variant in ODZ4 for bipolar disorder impacts on amygdala activation during reward processing. Bipolar Disord. 2013;15:440–5.
Article
CAS
PubMed
Google Scholar
Craddock N, Sklar P. Genetics of bipolar disorder. Lancet. 2013;381:1654–62.
Article
CAS
PubMed
Google Scholar
Suliman SG, Stanik J, McCulloch LJ, Wilson N, Edghill EL, Misovicova N, et al. Severe insulin resistance and intrauterine growth deficiency associated with haploinsufficiency for INSR and CHN2: new insights into synergistic pathways involved in growth and metabolism. Diabetes. 2009;58:2954–61.
Article
CAS
PubMed
PubMed Central
Google Scholar
Maeda S, Araki S, Babazono T, Toyoda M, Umezono T, Kawai K, et al. Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes. Diabetes. 2010;59:2075–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hu C, Zhang R, Yu W, Wang J, Wang C, Pang C, et al. CPVL/CHN2 genetic variant is associated with diabetic retinopathy in Chinese type 2 diabetic patients. Diabetes. 2011;60:3085–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gamboa-Melendez MA, Huerta-Chagoya A, Moreno-Macias H, Vazquez-Cardenas P, Ordonez-Sanchez ML, Rodriguez-Guillen R, et al. Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population. Diabetes. 2012;61:3314–21.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hayes MG, Pluzhnikov A, Miyake K, Sun Y, Ng MC, Roe CA, et al. Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies. Diabetes. 2007;56:3033–44.
Article
CAS
PubMed
Google Scholar
Takata A, Iwayama Y, Fukuo Y, Ikeda M, Okochi T, Maekawa M, et al. A population-specific uncommon variant in GRIN3A associated with schizophrenia. Biol Psychiatry. 2013;73:532–9.
Article
CAS
PubMed
Google Scholar
Shen YC, Liao DL, Chen JY, Wang YC, Lai IC, Liou YJ, et al. Exomic sequencing of the ionotropic glutamate receptor N-methyl-D-aspartate 3A gene (GRIN3A) reveals no association with schizophrenia. Schizophr Res. 2009;114:25–32.
Article
PubMed
Google Scholar
Diekstra FP, van Vught PW, van Rheenen W, Koppers M, Pasterkamp RJ, van Es MA, et al. UNC13A is a modifier of survival in amyotrophic lateral sclerosis. Neurobiol Aging. 2012;33:630.
Article
PubMed
CAS
Google Scholar
van Es MA, Veldink JH, Saris CG, Blauw HM, van Vught PW, Birve A, et al. Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet. 2009;41:1083–7.
Article
PubMed
CAS
Google Scholar
Daoud H, Belzil V, Desjarlais A, Camu W, Dion PA, Rouleau GA. Analysis of the UNC13A gene as a risk factor for sporadic amyotrophic lateral sclerosis. Arch Neurol. 2010;67:516–7.
Article
PubMed
Google Scholar
Koppers M, Groen EJ, Van Vught PW, Van Rheenen W, Witteveen E, Van Es MA, et al. Screening for rare variants in the coding region of ALS-associated genes at 9p21.2 and 19p13.3. Neurobiol Aging. 2013;34:1518 e5–7.
Article
CAS
Google Scholar