Tawse J. Consumer attitudes towards farm animals and their welfare: a pig production case study. Biosci Horizons. 2010; 3(2):156–65.
Article
Google Scholar
Mormede P, Terenina E. Molecular genetics of the adrenocortical axis and breeding for robustness. Domest Anim Endocrinol. 2012; 43(2):116–31.
Article
CAS
PubMed
Google Scholar
Mormede P, Foury A, Barat P, Corcuff JB, Terenina E, Marissal-Arvy N, et al. Molecular genetics of hypothalamic-pituitary-adrenal axis activity and function. Ann N Y Acad Sci. 2011; 1220(1):127–36. Available from: doi:10.1111/j.1749-6632.2010.05902.x.
Article
CAS
PubMed
Google Scholar
Song C, Jiang J, Han X, Yu G, Pang Y. Effect of immunological stress to neuroendocrine and gene expression in different swine breeds. Mol Biol Rep. 2014; 41(6):3569–76.
Article
CAS
PubMed
Google Scholar
Dantzer R, O’Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci. 2008; 9(1):46–56.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pavlov VA, Tracey KJ. Neural circuitry and immunity. Immunol Res. 2015; 63(1-3):38–57.
Article
CAS
PubMed
PubMed Central
Google Scholar
Irwin MR, Cole SW. Reciprocal regulation of the neural and innate immune systems. Nat Rev Immunol. 2011; 11(9):625–32.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cole SW. Elevating the perspective on human stress genomics. Psychoneuroendocrinology. 2010; 35(7):955–62.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lansade L, Valenchon M, Foury A, Neveux C, Cole SW, Layé S, et al. Behavioral and transcriptomic fingerprints of an enriched environment in horses (equus caballus). PloS ONE. 2014; 9(12):e114384.
Article
PubMed
PubMed Central
Google Scholar
Vedhara K, Gill S, Eldesouky L, Campbell BK, Arevalo JMG, Ma J, et al.Personality and gene expression: do individual differences exist in the leukocyte transcriptome?Psychoneuroendocrinology. 2015; 52:72–82.
Article
CAS
PubMed
Google Scholar
Sautron V, Terenina E, Gress L, Lippi Y, Billon Y, Larzul C, et al. Time course of the response to ACTH in pig: biological and transcriptomic study. BMC Genomics. 2015; 16(961):PMC4650497.
Google Scholar
Larzul C, Terenina E, Foury A, Billon Y, Louveau I, Merlot E, et al.The cortisol response to ACTH in pigs, heritability and influence of corticosteroid-binding globulin. Animal. 2015; 9(12):1929–34.
Article
CAS
PubMed
Google Scholar
Hou X, Zhang J, Ahmad H, Zhang H, Xu Z, Wang T. Evaluation of antioxidant activities of ampelopsin and its protective effect in lipopolysaccharide-induced oxidative stress piglets. PloS ONE. 2014; 9:e108314.
Article
PubMed
PubMed Central
Google Scholar
Westphal M, Stubbe H, Sielenkämper A, Borgulya R, Van Aken H, Ball C, et al.Terlipressin dose response in healthy and endotoxemic sheep: impact on cardiopulmonary performance and global oxygen transport. Intensive Care Med. 2003; 29(2):301–8.
Article
PubMed
Google Scholar
Bonnet A, Bevilacqua C, Benne F, Bodin L, Cotinot C, Liaubet L, et al.Transcriptome profiling of sheep granulosa cells and oocytes during early follicular development obtained by laser capture microdissection. BMC Genomics. 2011; 12(1):417.
Article
CAS
PubMed
PubMed Central
Google Scholar
Spurgeon SL, Jones RC, Ramakrishnan R. High throughput gene expression measurement with real time PCR in a microfluidic dynamic array. PLoS ONE. 2008; 3(466):e1662.
Article
PubMed
PubMed Central
Google Scholar
Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001; 29(9):e45.
Article
CAS
PubMed
PubMed Central
Google Scholar
R Core Team. R: A Language and Environment for Statistical Computing. Vienna; 2015. Available from: http://www.R-project.org.
Déjean S, Martin PGP, Baccini A, Besse P. Clustering time-series gene expression data using smoothing spline derivatives. EURASIP J Bioinforma Syst Biol. 2007; 2007(1):70561.
Google Scholar
Straube J, Gorse AD, PROOF Centre of Excellence Team, Huang BE, Lê Cao KA. A linear mixed model spline framework for analysing time course ‘omics’ data. PLoS ONE. 2015; 10(8):e0134–540.
Article
Google Scholar
Liquet B, Lê Cao KA, Hocini H, Thiébaut R. A novel approach for biomarker selection and the integration of repeated measures experiments from two assays. BMC Bioinformatics. 2012; 13(1):325.
Article
PubMed
PubMed Central
Google Scholar
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B. 1995; 57:289–300.
Google Scholar
Gao Y, Flori L, Lecardonnel J, Esquerré D, Hu ZL, Teillaud A, et al.Transcriptome analysis of porcine PBMCs after in vitro stimulation by LPS or PMA/ionomycin using an expression array targeting the pig immune response. BMC Genomics. 2010; 11:292.
Article
PubMed
PubMed Central
Google Scholar
Zhang B, Kirov S, Snoddy J. WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res. 2005; 1(W33):W741—8.
Google Scholar
Wang J, Duncan D, Shi Z, Zhang B. WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013. Nucleic Acids Res. 2013; 41(W1):W77—83.
Article
PubMed
Google Scholar
Thurstone LL. Multiple factor analysis. Psychol Rev. 1931; 38(5):406.
Article
Google Scholar
Williams PN, Collier CT, Carroll JA, Welsh TH, Laurenz JC. Temporal pattern and effect of sex on lipopolysaccharide-induced stress hormone and cytokine response in pigs. Domest Anim Endocrinol. 2009; 37(3):139–47.
Article
CAS
PubMed
Google Scholar
Rosadini CV, Kagan JC. Early innate immune responses to bacterial LPS. Curr Opin Immun. 2016; 44:14–19.
Article
Google Scholar
Myers MJ, Farrell DE, Baker JD, Cope CV, Evock-Clover CM, Steele NC. Challenge differentially affects cytokine production and metabolic status of growing and finishing swine. Domest Anim Endocrinol. 1999; 17(4):345–60.
Article
CAS
PubMed
Google Scholar
Dänicke S, Brosig B, Kersten S, Kluess J, Kahlert S, Panther P, et al.The Fusarium toxin deoxynivalenol (DON) modulates the LPS induced acute phase reaction in pigs. Toxicol Lett. 2013; 220(2):172–80.
Article
PubMed
Google Scholar
Llamas Moya S, Boyle L, Lynch P, Arkins S. Age-related changes in pro-inflammatory cytokines, acute phase proteins and cortisol concentrations in neonatal piglets. Neonatology. 2006; 91(1):44–8.
Article
PubMed
Google Scholar
Harizi H, Homo-Delarche F, Amrani A, Coulaud J, Mormede P. Marked genetic differences in the regulation of blood glucose under immune and restraint stress in mice reveals a wide range of corticosensitivity. J Neuroimmunol. 2007; 189(1):59–68.
Article
CAS
PubMed
Google Scholar
Sun H, Huang Y, Yin C, Guo J, Zhao R, Yang X. Lipopolysaccharide markedly changes glucose metabolism and mitochondrial function in the longissimus muscle of pigs. Animal. 2016; 10(7):1204–12.
Article
CAS
PubMed
Google Scholar
Eigler N, Saccà L, Sherwin RS. Synergistic interactions of physiologic increments of glucagon, epinephrine, and cortisol in the dog: a model for stress-induced hyperglycemia. J Clin Investi. 1979; 63(1):114.
Article
CAS
Google Scholar
Guo J, Liu Z, Sun H, Huang Y, Albrecht E, Zhao R, et al. Lipopolysaccharide challenge significantly influences lipid metabolism and proteome of white adipose tissue in growing pigs. Lipids Health Dis. 2015; 14:68.
Article
PubMed
PubMed Central
Google Scholar
Liu Z, Liu W, Huang Y, Guo J, Zhao R, Yang X. Lipopolysaccharide significantly influences the hepatic triglyceride metabolism in growing pigs. Lipids Health Dis. 2015; 14:64.
Article
PubMed
PubMed Central
Google Scholar
Stanek C, Reinhardt N, Diesing AK, Nossol C, Kahlert S, Panther P, et al.A chronic oral exposure of pigs with deoxynivalenol partially prevents the acute effects of lipopolysaccharides on hepatic histopathology and blood clinical chemistry. Toxicol Let. 2012; 215(3):193–200.
Article
CAS
Google Scholar
Trauner M, Fickert P, Stauber RE. Inflammation-induced cholestasis. J Gastroenterol Hepatol. 1999; 14(10):946–59.
Article
CAS
PubMed
Google Scholar
Liu W, Ouyang X, Yang J, Liu J, Li Q, Gu Y, et al.AP-1 activated by toll-like receptors regulates expression of IL-23 p19. J Biol Chem. 2009; 284(36):24006–16.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rohrbach S, Engelhardt S, Lohse MJ, Werdan K, Holtz J, Muller-Werdan U. Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6. Mol Med. 2007; 13(11/12):605–14.
CAS
PubMed
PubMed Central
Google Scholar
Kang SS, Woo SS, Im J, Yang JS, Yun CH, Ju HR, et al.Human placenta promotes IL-8 expression through activation of JNK/SAPK and transcription factors NF- κB and AP-1 in PMA-differentiated THP-1 cells. Int Immunopharmacol. 2007; 7(11):1488–95.
Article
CAS
PubMed
Google Scholar
Park J, Chung SW, Kim SH, Kim TS. Up-regulation of interleukin-4 production via NF-AT/AP-1 activation in T cells by biochanin A, a phytoestrogen and its metabolites. Toxicol Appl Pharmacol. 2006; 212(3):188–99.
Article
CAS
PubMed
Google Scholar
Hess J, Angel P, Schorpp-Kistner M. AP-1 subunits: quarrel and harmony among siblings. J Cell Sci. 2004; 117(25):5965–73.
Article
CAS
PubMed
Google Scholar
Donn R, Berry A, Stevens A, Farrow S, Betts J, Stevens R, et al.Use of gene expression profiling to identify a novel glucocorticoid sensitivity determining gene, BMPRII. FASEB J. 2007; 21(2):402–14.
Article
CAS
PubMed
Google Scholar
Thomas AV, Broers AD, Vandegaart HF, Desmecht DJM. Genomic structure, promoter analysis and expression of the porcine (Sus scrofa) TLR4 gene. Mol Immunol. 2006; 43(6):653–9.
Article
CAS
PubMed
Google Scholar
Clarke R, Tyson JJ, Dixon JM. Endocrine resistance in breast cancer – an overview and update. Mol Cellular Endocrinol. 2015; 418:22034.
Article
Google Scholar
Werling D, Jungi TW. TOLL-like receptors linking innate and adaptive immune response. Vet Immunol Immunopathol. 2003; 91(1):1–12.
Article
CAS
PubMed
Google Scholar
Borjigin L, Shimazu T, Katayama Y, Li M, Satoh T, Watanabe K, et al.Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine. Animal Sci J. 2016; 87(3):321–9.
Article
CAS
Google Scholar
Tan Y, Kagan JC. A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide. Mol Cell. 2014; 54:212–23.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lithgow P, Takamatsu H, Werling D, Dixon L, Chapman D. Correlation of cell surface marker expression with African swine fever virus infection. Vet Microbio. 2014; 168(2):413–9.
Article
CAS
Google Scholar
Niu P, Shabir N, Khatun A, Seo BJ, Gu S, Lee SM, et al.Effect of polymorphisms in the GBP1, Mx1 and CD163 genes on host responses to PRRSV infection in pigs. Vet Microbiol. 2016; 182:187–95.
Article
CAS
PubMed
Google Scholar
Caì Y, Postnikova EN, Bernbaum JG, Yú S, Mazur S, Deiuliis NM, et al. Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway. J Virol. 2015; 89(1):844–56.
Article
PubMed
Google Scholar
Sikorski K, Chmielewski S, Przybyl L, Heemann U, Wesoly J, Baumann M, et al.STAT1-mediated signal integration between IFN γ and LPS leads to increased EC and SMC activation and monocyte adhesion. Am J Physiol Cell Physiol. 2011; 300(6):C1337—44.
Article
PubMed
Google Scholar
Luu K, Greenhill CJ, Majoros A, Decker T, Jenkins BJ, Mansell A. STAT1 plays a role in TLR signal transduction and inflammatory responses. Immunol Cell Biol. 2014; 92(9):761–9.
Article
CAS
PubMed
Google Scholar
Mach N, Gao Y, Lemonnier G, Lecardonnel J, Oswald IP, Estellé J, et al.The peripheral blood transcriptome reflects variations in immunity traits in swine: towards the identification of biomarkers. BMC Genomics. 2013; 17(14):894.
Article
Google Scholar
Zhou CX, Zhou DH, Liu GX, Suo X, Zhu XQ. Transcriptomic analysis of porcine PBMCs infected with Toxoplasma gondii RH strain. Acta Tropica. 2016; 154:82–8.
Article
CAS
PubMed
Google Scholar
Zhao FR, Xie YL, Liu ZZ, Shao JJ, Li SF, Zhang YG, et al.Transcriptomic analysis of porcine PBMCs in response to FMDV infection. Acta Tropica. 2017; 173:69–75.
Article
CAS
PubMed
Google Scholar
Islam MA, Große-Brinkhaus C, Pröll MJ, Uddin MJ, Rony SA, Tesfaye D, et al. PBMC transcriptome profiles identifies potential candidate genes and functional networks controlling the innate and the adaptive immune response to PRRSV vaccine in Pietrain pig. PLoS ONE. 2017; 12(3):e0171828.
Article
PubMed
PubMed Central
Google Scholar
Donaldson L, Vuocolo T, Gray C, Strandberg Y, Reverter A, McWilliam S, et al.Construction and validation of a bovine innate immune microarray. BMC Genomics. 2005; 6:135.
Article
PubMed
PubMed Central
Google Scholar
Ledger TN, Pinton P, Bourges D, Roumi P, Salmon H, Oswald IP. Development of a macroarray to specifically analyze immunological gene expression in swine. Clin Diagn Lab Immunol. 2004; 11(4):691–8.
CAS
PubMed
PubMed Central
Google Scholar
Wells CA, Ravasi T, Faulkner GJ, Carninci P, Okazaki Y, Hayashizaki Y, et al.Genetic control of the innate immune response. BMC Immunol. 2003; 4:5.
Article
PubMed
PubMed Central
Google Scholar
Boldrick JC, Alizadeh AA, Diehn M, Dudoit S, Liu CL, Belcher CE, et al.Stereotyped and specific gene expression programs in human innate immune responses to bacteria. Proc Natl Acad Sci. 2002; 99(2):972–7.
Article
CAS
PubMed
PubMed Central
Google Scholar