VandenDriessche T, Ivics Z, Izsvak Z, Chuah MK. Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells. Blood. 2009;114:1461–8.
Article
PubMed
CAS
Google Scholar
Aronovich EL, McIvor RS, Hackett PB. The sleeping beauty transposon system: a non-viral vector for gene therapy. Hum Mol Genet. 2011;20:R14–20.
Article
PubMed
PubMed Central
CAS
Google Scholar
Kebriaei P, Izsvak Z, Narayanavari SA, Singh H, Ivics Z. Gene therapy with the sleeping beauty transposon system. Trends Genet. 2017;33:852–70.
Article
PubMed
CAS
Google Scholar
Woodard LE, Wilson MH. piggyBac-ing models and new therapeutic strategies. Trends Biotechnol. 2015;33:525–33.
Article
PubMed
PubMed Central
CAS
Google Scholar
Yum SY, Lee SJ, Kim HM, Choi WJ, Park JH, Lee WW, Kim HS, Kim HJ, Bae SH, Lee JH, et al. Efficient generation of transgenic cattle using the DNA transposon and their analysis by next-generation sequencing. Sci Rep. 2016;6:27185.
Article
PubMed
PubMed Central
CAS
Google Scholar
Garrels W, Mates L, Holler S, Dalda A, Taylor U, Petersen B, Niemann H, Izsvak Z, Ivics Z, Kues WA. Germline transgenic pigs by sleeping beauty transposition in porcine zygotes and targeted integration in the pig genome. PLoS One. 2011;6:e23573.
Article
PubMed
PubMed Central
CAS
Google Scholar
Garrels W, Talluri TR, Apfelbaum R, Carratala YP, Bosch P, Potzsch K, Grueso E, Ivics Z, Kues WA. One-step multiplex Transgenesis via sleeping beauty transposition in cattle. Sci Rep. 2016;6:21953.
Article
PubMed
PubMed Central
CAS
Google Scholar
Deng S, Li G, Yu K, Tian X, Wang F, Li W, Jiang W, Ji P, Han H, Fu J, et al. RNAi combining sleeping beauty transposon system inhibits ex vivo expression of foot-and-mouth disease virus VP1 in transgenic sheep cells. Sci Rep. 2017;7:10065.
Article
PubMed
PubMed Central
Google Scholar
Bai DP, Yang MM, Qu L, Chen YL. Generation of a transgenic cashmere goat using the piggyBac transposition system. Theriogenology. 2017;93:1–6.
Article
PubMed
CAS
Google Scholar
Carlson DF, Garbe JR, Tan W, Martin MJ, Dobrinsky JR, Hackett PB, Clark KJ, Fahrenkrug SC. Strategies for selection marker-free swine transgenesis using the sleeping beauty transposon system. Transgenic Res. 2011;20:1125–37.
Article
PubMed
CAS
Google Scholar
Ivics Z, Garrels W, Mates L, Yau TY, Bashir S, Zidek V, Landa V, Geurts A, Pravenec M, Rulicke T, et al. Germline transgenesis in pigs by cytoplasmic microinjection of sleeping beauty transposons. Nat Protoc. 2014;9:810–27.
Article
PubMed
CAS
Google Scholar
Hallet B, Sherratt DJ. Transposition and site-specific recombination: adapting DNA cut-and-paste mechanisms to a variety of genetic rearrangements. FEMS Microbiol Rev. 1997;21:157–78.
Article
PubMed
CAS
Google Scholar
Gogol-Doring A, Ammar I, Gupta S, Bunse M, Miskey C, Chen W, Uckert W, Schulz TF, Izsvak Z, Ivics Z. Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4+ T cells. Mol Ther. 2016;24:592–606.
Article
PubMed
PubMed Central
CAS
Google Scholar
Hackett PB, Largaespada DA, Switzer KC, Cooper LJ. Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy. Transl Res. 2013;161:265–83.
Article
PubMed
PubMed Central
CAS
Google Scholar
Williams DA. Sleeping beauty vector system moves toward human trials in the United States. Mol Ther. 2008;16:1515–6.
Article
PubMed
CAS
Google Scholar
Kebriaei P, Singh H, Huls MH, Figliola MJ, Bassett R, Olivares S, Jena B, Dawson MJ, Kumaresan PR, Su S, et al. Phase I trials using sleeping beauty to generate CD19-specific CAR T cells. J Clin Invest. 2016;126:3363–76.
Article
PubMed
PubMed Central
Google Scholar
Kebriaei P, Huls H, Jena B, Munsell M, Jackson R, Lee DA, Hackett PB, Rondon G, Shpall E, Champlin RE, et al. Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies. Hum Gene Ther. 2012;23:444–50.
Article
PubMed
CAS
Google Scholar
Moriarity BS, Largaespada DA. Sleeping beauty transposon insertional mutagenesis based mouse models for cancer gene discovery. Curr Opin Genet Dev. 2015;30:66–72.
Article
PubMed
PubMed Central
CAS
Google Scholar
Machado GM, Carvalho JO, Filho ES, Caixeta ES, Franco MM, Rumpf R, Dode MA. Effect of Percoll volume, duration and force of centrifugation, on in vitro production and sex ratio of bovine embryos. Theriogenology. 2009;71:1289–97.
Article
PubMed
CAS
Google Scholar
Lim KT, Jang G, Ko KH, Lee WW, Park HJ, Kim JJ, Lee SH, Hwang WS, Lee BC, Kang SK. Improved in vitro bovine embryo development and increased efficiency in producing viable calves using defined media. Theriogenology. 2007;67:293–302.
Article
PubMed
Google Scholar
Zhang R, Yin Y, Zhang Y, Li K, Zhu H, Gong Q, Wang J, Hu X, Li N. Molecular characterization of transgene integration by next-generation sequencing in transgenic cattle. PLoS One. 2012;7:e50348.
Article
PubMed
PubMed Central
CAS
Google Scholar
Roach JC, Glusman G, Smit AF, Huff CD, Hubley R, Shannon PT, Rowen L, Pant KP, Goodman N, Bamshad M, et al. Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science. 2010;328:636–9.
Article
PubMed
PubMed Central
CAS
Google Scholar
Soboleski MR, Oaks J, Halford WP. Green fluorescent protein is a quantitative reporter of gene expression in individual eukaryotic cells. FASEB J. 2005;19:440–2.
Article
PubMed
CAS
Google Scholar
Fortinea N, Trieu-Cuot P, Gaillot O, Pellegrini E, Berche P, Gaillard JL. Optimization of green fluorescent protein expression vectors for in vitro and in vivo detection of listeria monocytogenes. Res Microbiol. 2000;151:353–60.
Article
PubMed
CAS
Google Scholar
Tamada H, Kikyo N. Nuclear reprogramming in mammalian somatic cell nuclear cloning. Cytogenet Genome Res. 2004;105:285–91.
Article
PubMed
CAS
Google Scholar
Rideout WM 3rd, Eggan K, Jaenisch R. Nuclear cloning and epigenetic reprogramming of the genome. Science. 2001;293:1093–8.
Article
PubMed
CAS
Google Scholar
Wu SC, Meir YJ, Coates CJ, Handler AM, Pelczar P, Moisyadi S, Kaminski JM. piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells. Proc Natl Acad Sci U S A. 2006;103:15008–13.
Article
PubMed
PubMed Central
CAS
Google Scholar
Ding S, Wu X, Li G, Han M, Zhuang Y, Xu T. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell. 2005;122:473–83.
Article
PubMed
CAS
Google Scholar
Li T, Shuai L, Mao J, Wang X, Wang M, Zhang X, Wang L, Li Y, Li W, Zhou Q. Efficient production of fluorescent transgenic rats using the piggyBac transposon. Sci Rep. 2016;6:33225.
Article
PubMed
PubMed Central
CAS
Google Scholar
Jakobsen JE, Li J, Kragh PM, Moldt B, Lin L, Liu Y, Schmidt M, Winther KD, Schyth BD, Holm IE, et al. Pig transgenesis by sleeping beauty DNA transposition. Transgenic Res. 2011;20:533–45.
Article
PubMed
CAS
Google Scholar
Balciunas D, Davidson AE, Sivasubbu S, Hermanson SB, Welle Z, Ekker SC. Enhancer trapping in zebrafish using the sleeping beauty transposon. BMC Genomics. 2004;5:62.
Article
PubMed
PubMed Central
CAS
Google Scholar
Ivics Z, Mates L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, et al. Germline transgenesis in rodents by pronuclear microinjection of sleeping beauty transposons. Nat Protoc. 2014;9:773–93.
Article
PubMed
CAS
Google Scholar
Garcia Diaz AI, Moyon B, Coan PM, Alfazema N, Venda L, Woollard K, Aitman T. New Wistar Kyoto and spontaneously hypertensive rat transgenic models with ubiquitous expression of green fluorescent protein. Dis Model Mech. 2016;9:463–71.
Article
PubMed
PubMed Central
CAS
Google Scholar
Reichenbach M, Lim T, Reichenbach HD, Guengoer T, Habermann FA, Matthiesen M, Hofmann A, Weber F, Zerbe H, Grupp T, et al. Germ-line transmission of lentiviral PGK-EGFP integrants in transgenic cattle: new perspectives for experimental embryology. Transgenic Res. 2010;19:549–56.
Article
PubMed
CAS
Google Scholar
Saha S, Woodard LE, Charron EM, Welch RC, Rooney CM, Wilson MH. Evaluating the potential for undesired genomic effects of the piggyBac transposon system in human cells. Nucleic Acids Res. 2015;43:1770–82.
Article
PubMed
PubMed Central
CAS
Google Scholar
Katter K, Geurts AM, Hoffmann O, Mates L, Landa V, Hiripi L, Moreno C, Lazar J, Bashir S, Zidek V, et al. Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. FASEB J. 2013;27:930–41.
Article
PubMed
PubMed Central
CAS
Google Scholar
Fischer SE, Wienholds E, Plasterk RH. Regulated transposition of a fish transposon in the mouse germ line. Proc Natl Acad Sci U S A. 2001;98:6759–64.
Article
PubMed
PubMed Central
CAS
Google Scholar
Clark KJ, Urban MD, Skuster KJ, Ekker SC. Transgenic zebrafish using transposable elements. Methods Cell Biol. 2011;104:137–49.
Article
PubMed
PubMed Central
CAS
Google Scholar
Kerekes A, Hoffmann OI, Iski G, Liptak N, Gocza E, Kues WA, Bosze Z, Hiripi L. Secretion of a recombinant protein without a signal peptide by the exocrine glands of transgenic rabbits. PLoS One. 2017;12:e0187214.
Article
PubMed
PubMed Central
CAS
Google Scholar
Mukherjee A, Garrels W, Talluri TR, Tiedemann D, Bosze Z, Ivics Z, Kues WA. Expression of active fluorophore proteins in the milk of transgenic pigs bypassing the secretory pathway. Sci Rep. 2016;6:24464.
Article
PubMed
PubMed Central
CAS
Google Scholar
Yang B, Wang J, Tang B, Liu Y, Guo C, Yang P, Yu T, Li R, Zhao J, Zhang L, et al. Characterization of bioactive recombinant human lysozyme expressed in milk of cloned transgenic cattle. PLoS One. 2011;6:e17593.
Article
PubMed
PubMed Central
CAS
Google Scholar
Bryda EC, Pearson M, Agca Y, Bauer BA. Method for detection and identification of multiple chromosomal integration sites in transgenic animals created with lentivirus. BioTechniques. 2006;41:715–9.
Article
PubMed
CAS
Google Scholar
Park F. Lentiviral vectors: are they the future of animal transgenesis? Physiol Genomics. 2007;31:159–73.
Article
PubMed
CAS
Google Scholar
Jahner D, Jaenisch R. Integration of Moloney leukaemia virus into the germ line of mice: correlation between site of integration and virus activation. Nature. 1980;287:456–8.
Article
PubMed
CAS
Google Scholar
Garrick D, Fiering S, Martin DI, Whitelaw E. Repeat-induced gene silencing in mammals. Nat Genet. 1998;18:56–9.
Article
PubMed
CAS
Google Scholar
Ansari AM, Ahmed AK, Matsangos AE, Lay F, Born LJ, Marti G, Harmon JW, Sun Z. Cellular GFP toxicity and immunogenicity: potential confounders in in vivo cell tracking experiments. Stem Cell Rev. 2016;12:553–9.
Article
PubMed Central
CAS
Google Scholar
Brun-Hansen HC, Kampen AH, Lund A. Hematologic values in calves during the first 6 months of life. Vet Clin Pathol. 2006;35:182–7.
Article
PubMed
Google Scholar