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Volume 9 Supplement 2

IEEE 7th International Conference on Bioinformatics and Bioengineering at Harvard Medical School

Research

Edited by Mary Qu Yang, Jack Y Yang, Hamid R Arabnia and Youping Deng

IEEE 7th International Conference on Bioinformatics and Bioengineering at Harvard Medical School. Go to conference site.

Boston, MA, USA14-17 October 2007

  1. Supported by National Science Foundation (NSF), International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design and International Journal of Fun...

    Authors: Jack Y Yang, Mary Qu Yang, Hamid R Arabnia and Youping Deng

    Citation: BMC Genomics 2008 9(Suppl 2):I1

    Content type: Introductory Review

    Published on:

  2. Our first predictor of protein disorder was published just over a decade ago in the Proceedings of the IEEE International Conference on Neural Networks (Romero P, Obradovic Z, Kissinger C, Villafranca JE, Dunker ...

    Authors: A Keith Dunker, Christopher J Oldfield, Jingwei Meng, Pedro Romero, Jack Y Yang, Jessica Walton Chen, Vladimir Vacic, Zoran Obradovic and Vladimir N Uversky

    Citation: BMC Genomics 2008 9(Suppl 2):S1

    Content type: Research

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  3. Structural genomics efforts contribute new protein structures that often lack significant sequence and fold similarity to known proteins. Traditional sequence and structure-based methods may not be sufficient ...

    Authors: Inbal Halperin, Dariya S Glazer, Shirley Wu and Russ B Altman

    Citation: BMC Genomics 2008 9(Suppl 2):S2

    Content type: Research

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  6. Using genomic DNA as common reference in microarray experiments has recently been tested by different laboratories. Conflicting results have been reported with regard to the reliability of microarray results u...

    Authors: Yunfeng Yang, Mengxia Zhu, Liyou Wu and Jizhong Zhou

    Citation: BMC Genomics 2008 9(Suppl 2):S5

    Content type: Research

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  7. Sudden death syndrome (SDS) of soybean (Glycine max L. Merr.) is an economically important disease, caused by the semi-biotrophic fungus Fusarium solani f. sp. glycines, recently renamed Fusarium virguliforme (Fv...

    Authors: Jiazheng Yuan, Mengxia Zhu, David A Lightfoot, M Javed Iqbal, Jack Y Yang and Khalid Meksem

    Citation: BMC Genomics 2008 9(Suppl 2):S6

    Content type: Research

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  9. Many protein regions and some entire proteins have no definite tertiary structure, presenting instead as dynamic, disorder ensembles under different physiochemical circumstances. These proteins and regions are...

    Authors: Jack Y Yang and Mary Qu Yang

    Citation: BMC Genomics 2008 9(Suppl 2):S8

    Content type: Research

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  11. BLAST programs are very efficient in finding similarities for sequences. However for large datasets such as ESTs, manual extraction of the information from the batch BLAST output is needed. This can be time co...

    Authors: Mehdi Pirooznia, Edward J Perkins and Youping Deng

    Citation: BMC Genomics 2008 9(Suppl 2):S10

    Content type: Research

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  12. Microarray technology is widely applied to address complex scientific questions. However, there remain fundamental issues on how to design experiments to ensure that the resulting data enables robust statistic...

    Authors: Mehdi Pirooznia, Ping Gong, Jack Y Yang, Mary Qu Yang, Edward J Perkins and Youping Deng

    Citation: BMC Genomics 2008 9(Suppl 2):S11

    Content type: Research

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  13. As studies of molecular biology system attempt to achieve a comprehensive understanding of a particular system, Type 1 errors may be a significant problem. However, few investigators are inclined to accept the...

    Authors: Jian Wu, Nataliya I Lenchik and Ivan C Gerling

    Citation: BMC Genomics 2008 9(Suppl 2):S12

    Content type: Research

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  16. Because of the advent of high-throughput sequencing and the consequent reduction in the cost of sequencing, many organisms have been completely sequenced and most of their genes identified. It thus has become ...

    Authors: Feng Yue, Meng Zhang and Jijun Tang

    Citation: BMC Genomics 2008 9(Suppl 2):S15

    Content type: Research

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  17. Being formal, declarative knowledge representation models, ontologies help to address the problem of imprecise terminologies in biological and biomedical research. However, ontologies constructed under the aus...

    Authors: Jingshan Huang, Jiangbo Dang, Michael N Huhns and W Jim Zheng

    Citation: BMC Genomics 2008 9(Suppl 2):S16

    Content type: Research

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  21. Microarrays have the capacity to measure the expressions of thousands of genes in parallel over many experimental samples. The unsupervised classification technique of bicluster analysis has been employed prev...

    Authors: Kenneth Bryan and Pádraig Cunningham

    Citation: BMC Genomics 2008 9(Suppl 2):S20

    Content type: Research

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  22. Gene expression profiles based on microarray data are recognized as potential diagnostic indices of cancer. Molecular tumor classifications resulted from these data and learning algorithms have advanced our un...

    Authors: Rattikorn Hewett and Phongphun Kijsanayothin

    Citation: BMC Genomics 2008 9(Suppl 2):S21

    Content type: Research

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  23. Prostate cancer is one of the leading causes of cancer death in men. Androgen ablation, the most commonly-used therapy for progressive prostate cancer, is ineffective once the cancer cells become androgen-inde...

    Authors: Guohua Wang, Yadong Wang, Weixing Feng, Xin Wang, Jack Y Yang, Yuming Zhao, Yue Wang and Yunlong Liu

    Citation: BMC Genomics 2008 9(Suppl 2):S22

    Content type: Research

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  24. We present a mixture model-based analysis for identifying differences in the distribution of RNA polymerase II (Pol II) in transcribed regions, measured using ChIP-seq (chromatin immunoprecipitation following ...

    Authors: Weixing Feng, Yunlong Liu, Jiejun Wu, Kenneth P Nephew, Tim HM Huang and Lang Li

    Citation: BMC Genomics 2008 9(Suppl 2):S23

    Content type: Research

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  25. Dimension reduction is a critical issue in the analysis of microarray data, because the high dimensionality of gene expression microarray data set hurts generalization performance of classifiers. It consists o...

    Authors: Guo-Zheng Li, Hua-Long Bu, Mary Qu Yang, Xue-Qiang Zeng and Jack Y Yang

    Citation: BMC Genomics 2008 9(Suppl 2):S24

    Content type: Research

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  26. We have previously shown that using multiple prediction methods improves the accuracy of disorder predictions. It is, however, a time-consuming procedure, since individual outputs of multiple predictions have ...

    Authors: Philippe Lieutaud, Bruno Canard and Sonia Longhi

    Citation: BMC Genomics 2008 9(Suppl 2):S25

    Content type: Research

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  27. Protein interactions are essential for most cellular functions. Interactions mediated by domains that appear in a large number of proteins are of particular interest since they are expected to have an impact o...

    Authors: Siyuan Ren, Vladimir N Uversky, Zhengjun Chen, A Keith Dunker and Zoran Obradovic

    Citation: BMC Genomics 2008 9(Suppl 2):S26

    Content type: Research

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  28. Gene expression data usually contains a large number of genes, but a small number of samples. Feature selection for gene expression data aims at finding a set of genes that best discriminate biological samples...

    Authors: Yi Zhang, Chris Ding and Tao Li

    Citation: BMC Genomics 2008 9(Suppl 2):S27

    Content type: Research

    Published on:

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